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Q7V0R5

- PNP_PROMP

UniProt

Q7V0R5 - PNP_PROMP

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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Magnesium.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi495 – 4951MagnesiumUniRule annotation
Metal bindingi501 – 5011MagnesiumUniRule annotation

GO - Molecular functioni

  1. 3'-5'-exoribonuclease activity Source: InterPro
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP
  4. RNA binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. mRNA catabolic process Source: UniProtKB-HAMAP
  2. RNA processing Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

Magnesium, Metal-binding, RNA-binding

Enzyme and pathway databases

BioCyciPMAR59919:GJMQ-1224-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
Ordered Locus Names:PMM1191
OrganismiProchlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4)
Taxonomic identifieri59919 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000001026: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 721721Polyribonucleotide nucleotidyltransferasePRO_0000329773Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi59919.PMM1191.

Structurei

3D structure databases

ProteinModelPortaliQ7V0R5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini562 – 62160KHUniRule annotationAdd
BLAST
Domaini631 – 69969S1 motifUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation
Contains 1 KH domain.UniRule annotation
Contains 1 S1 motif domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG1185.
HOGENOMiHOG000218326.
KOiK00962.
OMAiILDHMEQ.
OrthoDBiEOG6WT8CC.

Family and domain databases

Gene3Di1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPiMF_01595. PNPase.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. S1_dom.
[Graphical view]
PANTHERiPTHR11252. PTHR11252. 1 hit.
PfamiPF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view]
PIRSFiPIRSF005499. PNPase. 1 hit.
SMARTiSM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7V0R5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEGKNTSITF DGREIRLTTG LYAPQAGGAV MIECGDTSLL VTATKTTKKQ
60 70 80 90 100
AADFLPLICD YEEKLYAAGR IPGGFMRREG RPPERATLIA RLIDRPMRPL
110 120 130 140 150
FPSWMRDEIQ IVASCLSLDE RVPADVLGVT GASIATLLAE IPFYGPMAAV
160 170 180 190 200
RVGLIGDDFI LNPSYREIEK GDLDIVVAGS PEGIVMIEAG ANQLSEQDTI
210 220 230 240 250
EAIDFGYEAV SELIKAQENL LKDLGIKQVK PLEPEEDKAL ATYLEKNCTK
260 270 280 290 300
PIDLILKKFD QSKEERDLEL DKIELEVQTK IDSLKDDNQL KVLTSENEKL
310 320 330 340 350
IHSDFKKLTK KLMRSQIINE GKRVDGRDLD EVRKISASAG ILPKRVHGSA
360 370 380 390 400
LFQRGLTQVL STTTLGTPSD AQEMDDLNPS TEKTYLHHYN FPPYSVGETR
410 420 430 440 450
PMRTPGRREI GHGALAERAI TPVLPGKETF PYVLRVVSEV LSSNGSTSMG
460 470 480 490 500
SVCGSTLSLL DAGVPLKAPV SGTAMGLIKE GKEVRILTDI QGIEDFLGDM
510 520 530 540 550
DFKVAGTEKG ITALQMDMKI TGLPVSVISD AIKKARPARL HILEKMQEAI
560 570 580 590 600
DKPQESLSPH APRLLSFRID PELIGTVIGP GGRTIKGITE RTNTKIDIED
610 620 630 640 650
GGIVTIASHD GAAAEEAQKI IEGLTRKVHE GEIFPGVVTR IIPIGAFVEI
660 670 680 690 700
LPGKEGMVHI SQLSEARVER VEDVVRQGDE VTVRVREIDS RGRINLTLRG
710 720
VAQNGGMSYP EPTPTPVAPL N
Length:721
Mass (Da):78,668
Last modified:October 1, 2003 - v1
Checksum:i48707658F837E130
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX548174 Genomic DNA. Translation: CAE19650.1.
RefSeqiNP_893308.1. NC_005072.1.

Genome annotation databases

EnsemblBacteriaiCAE19650; CAE19650; PMM1191.
GeneIDi1726709.
KEGGipmm:PMM1191.
PATRICi23033426. VBIProMar68066_1372.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX548174 Genomic DNA. Translation: CAE19650.1 .
RefSeqi NP_893308.1. NC_005072.1.

3D structure databases

ProteinModelPortali Q7V0R5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 59919.PMM1191.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE19650 ; CAE19650 ; PMM1191 .
GeneIDi 1726709.
KEGGi pmm:PMM1191.
PATRICi 23033426. VBIProMar68066_1372.

Phylogenomic databases

eggNOGi COG1185.
HOGENOMi HOG000218326.
KOi K00962.
OMAi ILDHMEQ.
OrthoDBi EOG6WT8CC.

Enzyme and pathway databases

BioCyci PMAR59919:GJMQ-1224-MONOMER.

Family and domain databases

Gene3Di 1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPi MF_01595. PNPase.
InterProi IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. S1_dom.
[Graphical view ]
PANTHERi PTHR11252. PTHR11252. 1 hit.
Pfami PF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view ]
PIRSFi PIRSF005499. PNPase. 1 hit.
SMARTi SM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
PROSITEi PS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CCMP1986 / MED4.

Entry informationi

Entry nameiPNP_PROMP
AccessioniPrimary (citable) accession number: Q7V0R5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: October 1, 2003
Last modified: October 29, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3