Q7V0D0 (FABZ_PROMP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Short name=(3R)-hydroxymyristoyl ACP dehydrase
EC=4.2.1.-

Gene names

Name:	fabZ
Ordered Locus Names:	PMM1336

Organism

Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4) [Complete proteome] [HAMAP]

Taxonomic identifier

59919 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	152 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in saturated fatty acids biosynthesis. HAMAP MF_00406
Subcellular location	Cytoplasm By similarity HAMAP MF_00406.
Sequence similarities	Belongs to the thioester dehydratase family. FabZ subfamily.

Ontologies

Keywords
Biological process	Lipid A biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: InterPro lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	hydro-lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 152	152	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase HAMAP MF_00406		PRO_0000091712
Sites
	Active site	58	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7V0D0 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 9D4862525527EB62	FASTA	152	16,809
	10 20 30 40 50 60 MEQQLSTENN QLSSEEILGL LPHRFPFALI DRVIEHVPGK KAVALKNVTI NEPQFQGHFP 70 80 90 100 110 120 ERPLMPGVLI VEAMAQVGGI IVTQMPDLPK GLFVFAGINN VKFRRPVVPG DQLVITCELL 130 140 150 SIKRQRFGKV KGEAHVDGKL VCSGELMFSL VD

References

[1]

"Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation." Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A., Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L., Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C. , Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R., Chisholm S.W. Nature 424:1042-1047(2003) [PubMed: 12917642] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CCMP1986 / MED4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX548174 Genomic DNA. Translation: CAE19795.1.
RefSeq	NP_893453.1. NC_005072.1.
3D structure databases
ProteinModelPortal	Q7V0D0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7V0D0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1726830.
GenomeReviews	Gene locus PMM1336 in contig BX548174_GR.
KEGG	pmm:PMM1336.
NMPDR	fig|59919.1.peg.1332.
PATRIC	23033740. VBIProMar68066_1524.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0764.
HOGENOM	HBG433282.
OMA	NVSANES.
PhylomeDB	Q7V0D0.
ProtClustDB	PRK00006.
Enzyme and pathway databases
BioCyc	PMAR167540:PMM1336-MONOMER.
Family and domain databases
HAMAP	MF_00406. FabZ. [Tree]
InterPro	IPR013114. FabA_FabZ. IPR010084. FabZ. [Graphical view]
KO	K02372.
Pfam	PF07977. FabA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01750. FabZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FABZ_PROMP

Accession

Primary (citable) accession number: Q7V0D0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 24, 2004
Last sequence update:	October 1, 2003
Last modified:	January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program