Q7V0C9 (Q7V0C9_PROMP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-0-acyl N-acetylglucosamine deacetylase EMBL CAE19796.1
EC=3.5.1.- EMBL CAE19796.1

Gene names

Name:	lpxC EMBL CAE19796.1
Ordered Locus Names:	PMM1337

Organism

Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4) [Complete proteome] [HAMAP]

Taxonomic identifier

59919 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	278 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870 EMBL CAE19796.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7V0C9 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 5372CF4C59BBBC42	FASTA	278	30,700
	10 20 30 40 50 60 MFSWPSNYDS CYTLSGVITK EGVGLHSGEK TRIKISPFEK EGFYVSFSDK PDDIFQLNQN 70 80 90 100 110 120 LIGSTMLCTA VKLAGRNLYT IEHLLSSLAG CGLSYIHIEV DGKEIPLLDG SAIQWVKAFE 130 140 150 160 170 180 EVGIKRVPKP KNFIREVNKS MIFNKDSSVI ALTPSNKITI ISTINFSYKA IGNQTYVIDL 190 200 210 220 230 240 NPKSFVENIA PARTFGFKDQ FQELSELGLI KGGSLENALV CDGDKWVNPP LRFSNEPIRH 250 260 270 KILDLIGDLA LVGLPKAQIL VYKGSHSLNA LLASSLKN

References

[1]

"Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation." Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A., Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L., Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C. , Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R., Chisholm S.W. Nature 424:1042-1047(2003) [PubMed: 12917642] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX548174 Genomic DNA. Translation: CAE19796.1.
RefSeq	NP_893454.1. NC_005072.1.
3D structure databases
ProteinModelPortal	Q7V0C9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7V0C9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1726857.
GenomeReviews	Gene locus PMM1337 in contig BX548174_GR.
KEGG	pmm:PMM1337.
NMPDR	fig|59919.1.peg.1333.
PATRIC	23033742. VBIProMar68066_1525.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0774.
HOGENOM	HBG482342.
OMA	DGSAIQW.
PhylomeDB	Q7V0C9.
ProtClustDB	PRK13186.
Enzyme and pathway databases
BioCyc	PMAR167540:PMM1337-MONOMER.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
TIGRFAMs	TIGR00325. LpxC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q7V0C9_PROMP

Accession

Primary (citable) accession number: Q7V0C9

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)