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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei175 – 1751UniRule annotation
Active sitei630 – 6301UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciPMAR59919:GJMQ-1618-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:PMM1575
OrganismiProchlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4)
Taxonomic identifieri59919 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000001026 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 989989Phosphoenolpyruvate carboxylasePRO_0000166612Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi59919.PMM1575.

Structurei

3D structure databases

ProteinModelPortaliQ7UZT0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7UZT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESMKQFKNN NVDLISNNDP LDKNRALIED LWESVLREEC PDDQANRLIQ
60 70 80 90 100
LKELSYSNKV EEYSPKNFKT EIVDIVNSMD LAESISAARA FSLYFQLVNI
110 120 130 140 150
LEQRVEEDRY IQSFTNQNVK KSHDNLDPFA PALARQNAPV TFKELFFRLR
160 170 180 190 200
RLNVPPGKLE ELLQEMDIRL VFTAHPTEIV RHTIRHKQTR VANLLQKIQV
210 220 230 240 250
EKFLTIEDIK SLKIQLKEEI RLWWRTDELH QFKPSVIDEV DYALHYFQQV
260 270 280 290 300
LFDAMPQLRG RISSALTENY PDVQMPTESF CTFGSWVGSD RDGNPSVTPE
310 320 330 340 350
ITWRTACYQR QLMLERYIKA TSNLRDQLSV SMQWSQVSSS LLESLETDRV
360 370 380 390 400
KFPEIYEARA TRYRSEPYRL KLSYILEKLR LTHERNNLLS EGGWKLSLER
410 420 430 440 450
ESDNKNLELV EKLHYKSVDE FTYDLELIKN SLNSTDLTCE AVNKLLTQVH
460 470 480 490 500
IFGFSLASLD IRQESTRHSD AIQELTNYLE LPKQYDQMSE KDRIQWLNEE
510 520 530 540 550
LNTKRPLIPS EVNWNKSTEE TFSVFKMVKR LQEEFGSRIC HSYVISMSHS
560 570 580 590 600
ASDLLEVLLL AKEMGLIDQG SQKSTLLVVP LFETVEDLQR APDVMEQLFQ
610 620 630 640 650
LDFYKSLLPK VGESFKPLQE LMLGYSDSNK DSGFLSSNWE IHRAQIALQN
660 670 680 690 700
LSSRNNILLR LFHGRGGSVG RGGGPAYQAI LAQPSGTLKG RIKITEQGEV
710 720 730 740 750
LASKYSLPEL ALYNLETVTT AVIQNSLVNN RLDATPEWND LMTRLAETSR
760 770 780 790 800
IQYRKLVHEN PNLLTFFQEV TPIEEISKLQ ISSRPARRKK GAKDLSSLRA
810 820 830 840 850
IPWVFGWTQS RFLLPSWFGV GTALSVELKS DPEQIELLRV LHQRWPFFRM
860 870 880 890 900
LISKVEMTLS KVDLEVAKYY VDTLGSKENS KSFEEIFDVI SKEYNLTKSL
910 920 930 940 950
VLEITGKNKL LESDRDLRSS VNLRNKTIIP LGFLQVSLLR RLRDQTRQPP
960 970 980
ISEFIEDRIE SKRAYSRSEL LRGALLTING IAAGMRNTG
Length:989
Mass (Da):114,381
Last modified:October 1, 2003 - v1
Checksum:iDD384EF4726C83D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX548174 Genomic DNA. Translation: CAE20034.1.
RefSeqiNP_893692.1. NC_005072.1.

Genome annotation databases

EnsemblBacteriaiCAE20034; CAE20034; PMM1575.
KEGGipmm:PMM1575.
PATRICi23034336. VBIProMar68066_1818.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX548174 Genomic DNA. Translation: CAE20034.1.
RefSeqiNP_893692.1. NC_005072.1.

3D structure databases

ProteinModelPortaliQ7UZT0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi59919.PMM1575.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAE20034; CAE20034; PMM1575.
KEGGipmm:PMM1575.
PATRICi23034336. VBIProMar68066_1818.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciPMAR59919:GJMQ-1618-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CCMP1986 / MED4.

Entry informationi

Entry nameiCAPP_PROMP
AccessioniPrimary (citable) accession number: Q7UZT0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: October 1, 2003
Last modified: April 1, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.