Reviewed, UniProtKB/Swiss-Prot Q7UX42 (SYQ_RHOBA)

Names and origin

Protein names

Recommended name:
    Glutaminyl-tRNA synthetase
    EC=6.1.1.18
Alternative name(s):
    Glutamine--tRNA ligase
      Short name=GlnRS

Gene names

Name:	glnS
Ordered Locus Names:	RB1578

Organism

Rhodopirellula baltica [Complete proteome] [HAMAP]

Taxonomic identifier

265606 [NCBI]

Taxonomic lineage

Bacteria › Planctomycetes › Planctomycetacia › Planctomycetales › Planctomycetaceae › Rhodopirellula

Protein attributes

Sequence length	601 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP MF_00126
Subunit structure	Monomer By similarity. HAMAP MF_00126
Subcellular location	Cytoplasm HAMAP MF_00126.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glutaminyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro glutamyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glutamine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 601	601	Glutaminyl-tRNA synthetase HAMAP MF_00126		PRO_0000195847
Regions
	Motif	76 – 86	11	"HIGH" region HAMAP MF_00126
	Motif	308 – 312	5	"KMSKS" region HAMAP MF_00126
Sites
	Binding site	311	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7UX42-1 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 0C6B526811FF4CD3	FASTA	601	68,668
	10 20 30 40 50 60 MARANRGEHS TLSTFWQSRH NAASFDPLYR RIDVNAPEPS DSATPEKTPS KHFIRQAIDA 70 80 90 100 110 120 DLASGRFDGV ATRFPPEPNG YLHIGHAKSI CLNFGLAKDM GGTCNLRFDD TNPIKEDTEY 130 140 150 160 170 180 VDSIQEDVRW LGFEWDNLHF ASDYFDQLYD WAEQLVKDGK AYVCDLTAEE TREYRGTLTE 190 200 210 220 230 240 PGKNSPHRDR TPEKNLELLR AMKAGKFKDG EKTLRAKIDM ASPNINLRDP VMYRIAHVPH 250 260 270 280 290 300 HRTGDKWCIY PMYDWAHGQS DSLEKITFSI CTLEFEHHRP LYNWYCENLG IHHPRQIEFA 310 320 330 340 350 360 RLNMTFTVMS KRKLLQLVKE NHVTGWDDPR MPTLVGLRRR GYTPESIRSF CADIGVAKFN 370 380 390 400 410 420 STIDVIRLEN SVREHLNSVA PRRMAVLDPI KLTITNWPEG KVEMMNAINN PEDESAGSRE 430 440 450 460 470 480 IPFSGELYIE TEDFREEAPR KFFRLKKGGS VRLRSGYIVD CHDVVKDADG NVTEVLCTYD 490 500 510 520 530 540 PETKSGEDTS GRKVKGTIHW VSREHAQKVT VRNYDRLFKV ENPDASSDTG SFLDHLNPDS 550 560 570 580 590 600 LTTLTAHVEP ALAEAAVGDR VQFERLGYYV VDPDSTDGEI IFNRIVPLRD TWGKIEAKGK K

References

[1]

"Complete genome sequence of the marine planctomycete Pirellula sp. strain 1." Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W., Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R., Reinhardt R. Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003) [PubMed: 12835416] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SH1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX294135 Genomic DNA. Translation: CAD72170.1.
RefSeq	NP_864489.1.
3D structure databases
SMR	Q7UX42. Positions 52-591.
ModBase	Search...
Genome annotation databases
GeneID	1794210.
KEGG	rba:RB1578.
NMPDR	fig|243090.1.peg.830.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG334108.
OMA	RMPTIAG.
PhylomeDB	Q7UX42.
Enzyme and pathway databases
BioCyc	PSP117:RB1578-MONOMER.
BRENDA	6.1.1.18. 280490.
Family and domain databases
HAMAP	MF_00126. Gln_tRNA_synth. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR004514. Gln-tRNA-synth_Ic. IPR000924. Glu/Gln-tRNA-synth_Ic. IPR020061. Glu/Gln-tRNA-synth_Ic_a-bdl. IPR020058. Glu/Gln-tRNA-synth_Ic_cat-dom. IPR020059. Glu/Gln-tRNA-synth_Ic_codon-bd. IPR020060. Glu/Gln-tRNA-synth_Ic_N. IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl. IPR011035. Ribosomal_L25/Gln-tRNA_synth. [Graphical view]
Gene3D	G3DSA:1.10.1160.10. Glu/Gln-tRNA-synth_Ic_a-bdl. 1 hit. G3DSA:2.40.240.10. Rbsml_L25/Gln-tRNA_synth_b-brl. 1 hit.
PANTHER	PTHR10119:SF3. GlnS. 1 hit. PTHR10119. Glu_tRNA-synt_1c. 1 hit.
Pfam	PF00749. tRNA-synt_1c. 1 hit. PF03950. tRNA-synt_1c_C. 1 hit. [Graphical view]
PRINTS	PR00987. TRNASYNTHGLU.
TIGRFAMs	TIGR00440. glnS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYQ_RHOBA

Accession

Primary (citable) accession number: Q7UX42

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2004
Last sequence update:	October 1, 2003
Last modified:	February 9, 2010
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)