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Protein

Na(+)-translocating NADH-quinone reductase subunit A

Gene

nqrA

Organism
Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na+ ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.UniRule annotation

Catalytic activityi

NADH + ubiquinone + n Na+(In) = NAD+ + ubiquinol + n Na+(Out).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

NAD, Sodium, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
Na(+)-translocating NADH-quinone reductase subunit AUniRule annotation (EC:1.6.5.8UniRule annotation)
Short name:
Na(+)-NQR subunit AUniRule annotation
Short name:
Na(+)-translocating NQR subunit AUniRule annotation
Alternative name(s):
NQR complex subunit AUniRule annotation
NQR-1 subunit AUniRule annotation
Gene namesi
Name:nqrAUniRule annotation
Ordered Locus Names:RB1831
OrganismiRhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)
Taxonomic identifieri243090 [NCBI]
Taxonomic lineageiBacteriaPlanctomycetesPlanctomycetiaPlanctomycetalesPlanctomycetaceaeRhodopirellula
Proteomesi
  • UP000001025 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 456456Na(+)-translocating NADH-quinone reductase subunit APRO_0000227020Add
BLAST

Interactioni

Subunit structurei

Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.UniRule annotation

Protein-protein interaction databases

STRINGi243090.RB1831.

Family & Domainsi

Sequence similaritiesi

Belongs to the NqrA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWQ. Bacteria.
COG1726. LUCA.
HOGENOMiHOG000273652.
InParanoidiQ7UWS5.
KOiK00346.
OrthoDBiPOG091H03YP.

Family and domain databases

HAMAPiMF_00425. NqrA. 1 hit.
InterProiIPR008703. NqrA.
IPR022615. NqrA_C_domain.
[Graphical view]
PfamiPF05896. NQRA. 1 hit.
PF11973. NQRA_SLBB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01936. nqrA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7UWS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTQSVTRI KKGLDLPITG CPEQHMEAGP AIRQVALLGD DYIGMKPTML
60 70 80 90 100
VSAGDRVVLG QPVFEDKKTP GVIYTAPASG TVVDVVRGAK RKFEAVVIDV
110 120 130 140 150
DNDSTETTTI DGIAGSDPIS IAREKLVDGL VQIGLWSAFR TRPFGKVPTI
160 170 180 190 200
ESRPHSIFVT AIDTNPLAAD PAVVLADRKD QFVIGLQALT RLTDGAVHLC
210 220 230 240 250
QAEKASIPGG DVAGVQSASF AGPHPAGLPG THIHHLDPVS LNKTVWYIGY
260 270 280 290 300
QDVIAIGSFL QTGQLDTRRV ISLAGPKVNQ PRLIETRLGA CIDELIDGEV
310 320 330 340 350
DTSVKLRVIS GSVLNGHIAT APHQFLGRYD NQVSVIEEGD HREFLGWQKP
360 370 380 390 400
GFDKFSVSRI FASAMTPDRK FDFTSSTGGS ERAMVPLGTY EKVMPMDILA
410 420 430 440 450
TQLLRALIVR DTDSAQQLGV LELEEEDLAL CTFVCPGKYE YGSLIRENLT

TIEREG
Length:456
Mass (Da):49,195
Last modified:March 7, 2006 - v2
Checksum:i4B016F907FF0FB47
GO

Sequence cautioni

The sequence CAD72287 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX294135 Genomic DNA. Translation: CAD72287.1. Different initiation.
RefSeqiNP_864606.1. NC_005027.1.

Genome annotation databases

EnsemblBacteriaiCAD72287; CAD72287; RB1831.
GeneIDi1796057.
KEGGirba:RB1831.
PATRICi23243101. VBIRhoBal59814_0840.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX294135 Genomic DNA. Translation: CAD72287.1. Different initiation.
RefSeqiNP_864606.1. NC_005027.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243090.RB1831.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAD72287; CAD72287; RB1831.
GeneIDi1796057.
KEGGirba:RB1831.
PATRICi23243101. VBIRhoBal59814_0840.

Phylogenomic databases

eggNOGiENOG4105DWQ. Bacteria.
COG1726. LUCA.
HOGENOMiHOG000273652.
InParanoidiQ7UWS5.
KOiK00346.
OrthoDBiPOG091H03YP.

Family and domain databases

HAMAPiMF_00425. NqrA. 1 hit.
InterProiIPR008703. NqrA.
IPR022615. NqrA_C_domain.
[Graphical view]
PfamiPF05896. NQRA. 1 hit.
PF11973. NQRA_SLBB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01936. nqrA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNQRA_RHOBA
AccessioniPrimary (citable) accession number: Q7UWS5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: March 7, 2006
Last modified: September 7, 2016
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.