Q7UVC4 (Q7UVC4_RHOBA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthetase EMBL CAD72801.1

Gene names

Name:	lpxB EMBL CAD72801.1
Ordered Locus Names:	RB2725

Organism

Rhodopirellula baltica (strain SH1)

Taxonomic identifier

243090 [NCBI]

Taxonomic lineage

Bacteria › Planctomycetes › Planctomycetacia › Planctomycetales › Planctomycetaceae › Rhodopirellula

Protein attributes

Sequence length	427 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7UVC4 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: EC6657E52CC798D2	FASTA	427	48,245
	10 20 30 40 50 60 MLHDRRGPSH VTKTIFFSVG EPSGDQHAAR LIRQLANPGG MAMRNDERII CRGFGGPSML 70 80 90 100 110 120 AAGCRVDLDL TRHAVVGIVE VLPKLREFFR FADQAEDIFR SGSVDSVVLV DFPGFNWHIA 130 140 150 160 170 180 KRAKKYGIPV HYYCPPQLWA WGAWRVRKMK RSVDHVVAVL PVEQSFFNRH QIPVSLVGHP 190 200 210 220 230 240 FFDAVAEQKL DTAVMRRFQS QQNSGDRVVA VLPGSRDHEV RANFPIQLET IRRLDRELSQ 250 260 270 280 290 300 SGENVRFAVA AYRDKQCLWC REQLSEEDKD LPIDFYVDCT SEIIEAAHCA MMVSGSVSLE 310 320 330 340 350 360 LLARETPAAV IYRVGRVLHA VGKRVLKIDS VTLPNLMAGR KLFPEFISVG DPAPAVDFLT 370 380 390 400 410 420 ETMRAMLQDS FYYAKIRRDL QKLRDEHARP GASQRAAELL RSKLFGDLET LPEKNSFGMQ TQMRDAA

References

[1]

"Complete genome sequence of the marine planctomycete Pirellula sp. strain 1." Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W., Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R., Reinhardt R. Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003) [PubMed: 12835416] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SH1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX294137 Genomic DNA. Translation: CAD72801.1.
RefSeq	NP_865117.1. NC_005027.1.
3D structure databases
ProteinModelPortal	Q7UVC4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1793565.
GenomeReviews	Gene locus RB2725 in contig BX119912_GR.
KEGG	rba:RB2725.
NMPDR	fig|243090.1.peg.1457.
PATRIC	23243935. VBIRhoBal59814_1253.
Phylogenomic databases
OMA	PDFNLGL.
PhylomeDB	Q7UVC4.
ProtClustDB	CLSK2758715.
Enzyme and pathway databases
BioCyc	PSP117:RB2725-MONOMER.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q7UVC4_RHOBA

Accession

Primary (citable) accession number: Q7UVC4

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)