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Q7UU96 (Q7UU96_RHOBA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyruvate dehydrogenase E1 component PIRNR PIRNR000156
EC=1.2.4.1 PIRNR PIRNR000156
Gene names
Ordered Locus Names:RB3424
OrganismRhodopirellula baltica (strain SH1)
Taxonomic identifier243090 [NCBI]
Taxonomic lineageBacteria › Planctomycetes › Planctomycetacia › Planctomycetales › Planctomycetaceae › Rhodopirellula

Protein attributes

Sequence length910 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity. PIRNR PIRNR000156

Catalytic activity

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2. PIRNR PIRNR000156

Cofactor

Thiamine pyrophosphate By similarity. PIRNR PIRNR000156

Sequences

Sequence LengthMass (Da)Tools
Q7UU96 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: A8A04C003CD8D7F8

FASTA910101,493
        10         20         30         40         50         60 
MSESKSVAQA EISQNLGELQ HSPDVDVDSA ETQEWISSLE YVLQSKGPER VKFLIDQLRD 

        70         80         90        100        110        120 
RAAEEGVPLS SDTSTPYVNT IPPHEQPAYP GNRELERRIK SIIRWNAMAM VVRANKRPGG 

       130        140        150        160        170        180 
VGGHISTFAS SATLYEVAFN HFFQGRGEDG YSGDSIYFQG HASPGMYSRA YLEGRLSDEN 

       190        200        210        220        230        240 
LDNFRRELAP GGGLSSYPHP WLMPGFWEYP TVSMGLGPIM AIYQARFNEY LNDRGIKDTK 

       250        260        270        280        290        300 
GQKVWAFLGD GECDEPETLG AIGLASREKL DNLIFVINCN LQRLDGPVRG NSKIIQELES 

       310        320        330        340        350        360 
IFHGAGWNVI KVVWGGEWDE LLARDTTGLL AKRMNEVVDG QYQKYTSMPG SYIREHFFGK 

       370        380        390        400        410        420 
YPELLELVKH LSDEKLEKIR RGGHDPEKVY AAYHRATTLN NGKPTVILAK TVKGYGLGEA 

       430        440        450        460        470        480 
GEGRNVAHNQ KKMNEAELLE FRTRFGIPIS DEKVGEAPFY KPPANSTEIK YLKTRRETLG 

       490        500        510        520        530        540 
GPVPSRPTEH PKLEIPALDV FQKFVAKRTD NKEVSTTFAA VQMLISMCRD KSIGKYVVPI 

       550        560        570        580        590        600 
VPDESRTFGM EGMFKQFGIY AHAGQLYEPT DSDQVAYYKE AQDGQILEEG ITECGSMSSF 

       610        620        630        640        650        660 
NAAGTAYSCH GVNMIPFYIY YSMFGFQRIG DSIWAAADMR AKGFLVGGTA GRTTLNGEGL 

       670        680        690        700        710        720 
QHQDGHSLLN AIAFPTVRAY DPAFAYEVTV IVHEGLKRMY EEGEECLYYI TAENEAYVQP 

       730        740        750        760        770        780 
EIPEGCEEGI IKGMYKFNSR EVDGAKARVQ LFGSGAILNS ALKAQEILAE KYNIASDVWS 

       790        800        810        820        830        840 
VTSYTLLRRD AHSVERWNRL HPTETPRKSY LEEVLEGVEG PFISASDYVR ALGEQLTPWI 

       850        860        870        880        890        900 
PGDYYVLGTD GMGRSETREA LRRHFEVDAE SITIAALGRL AKAGTFEAAD VAQAIKDLDY 

       910 
DPDKVDPYFA

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References

[1]"Complete genome sequence of the marine planctomycete Pirellula sp. strain 1."
Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W., Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R., Reinhardt R.
Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003) [PubMed: 12835416] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SH1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX294138 Genomic DNA. Translation: CAD73186.1.
RefSeqNP_865502.1. NC_005027.1.

3D structure databases

ProteinModelPortalQ7UU96.
SMRQ7UU96. Positions 75-910.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1795563.
GenomeReviewsGene locus RB3424 in contig BX119912_GR.
KEGGrba:RB3424.
NMPDRfig|243090.1.peg.1842.
PATRIC23244591. VBIRhoBal59814_1580.

Phylogenomic databases

HOGENOMHBG289271.
OMADRHFVVL.
PhylomeDBQ7UU96.
ProtClustDBPRK09405.

Enzyme and pathway databases

BioCycPSP117:RB3424-MONOMER.

Family and domain databases

InterProIPR004660. 2-oxoA_DH_E1.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK00163.
PANTHERPTHR11624:SF37. PTHR11624:SF37. 1 hit.
PfamPF00456. Transketolase_N. 2 hits.
[Graphical view]
PIRSFPIRSF000156. Pyruvate_dh_E1. 1 hit.
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00759. AceE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ7UU96_RHOBA
AccessionPrimary (citable) accession number: Q7UU96
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info