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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi488MagnesiumUniRule annotation1
Metal bindingi494MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, RNA-binding, Transferase
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
Ordered Locus Names:RB5804
OrganismiRhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)
Taxonomic identifieri243090 [NCBI]
Taxonomic lineageiBacteriaPlanctomycetesPlanctomycetiaPlanctomycetalesPlanctomycetaceaeRhodopirellula
Proteomesi
  • UP000001025 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003298081 – 753Polyribonucleotide nucleotidyltransferaseAdd BLAST753

Proteomic databases

PRIDEiQ7UR95

Interactioni

Protein-protein interaction databases

STRINGi243090.RB5804

Structurei

3D structure databases

ProteinModelPortaliQ7UR95
SMRiQ7UR95
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini555 – 614KHUniRule annotationAdd BLAST60
Domaini624 – 692S1 motifUniRule annotationAdd BLAST69

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C62 Bacteria
COG1185 LUCA
HOGENOMiHOG000218326
InParanoidiQ7UR95
KOiK00962
OrthoDBiPOG091H00M0

Family and domain databases

Gene3Di3.30.1370.10, 1 hit
3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR036456 PNPase_PH_RNA-bd_sf
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 1 hit
PF00575 S1, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF46915 SSF46915, 1 hit
SSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50084 KH_TYPE_1, 1 hit
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

Q7UR95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVQKVRVER KIGDSVLSFE TGHIAKQAAG SVLVQYGETV VLVAAASGTP
60 70 80 90 100
RPGIDFFPLM CDYRERLAAA GKFPGGFLKR EGRPSTKEIL SSRLMDRPIR
110 120 130 140 150
PLWPAGYKDE VQVQACVIAS DLQNDGDVLA MIGGATALHI SPLPFKGPLG
160 170 180 190 200
SVRVGKVDGK LVAFPTADQL EQSELDMIVS GSRDMVAMIE GFANEMPEDE
210 220 230 240 250
MMEAIGFAHD AIREVIDLQE EFYKKVNPEK TPYQSPEDDG LLQRLTDAYY
260 270 280 290 300
SDFKTAQQTS GKQARAEAVR AVRDRAMADV IPDPNAADAV CVNRFKSVWH
310 320 330 340 350
DLEEKVVRDL ILAGTRPDGR DHNSLRAIHC ETDLLPRVHG SALFQRGETQ
360 370 380 390 400
ALITIALGTS RDEQRVDGLQ DEYSKKFMLD YNFPSYSVGE CRPIRGPGRR
410 420 430 440 450
EIGHGCLAER SVAPVLPSAD DFPYTIRVIS DITESNGSSS MASVCGATLG
460 470 480 490 500
LMASGVPISN PVAGISVGLV QDGPDNWCLI TDILGTEDHF GDMDFKIAGT
510 520 530 540 550
QNGITGIQLD LKVTGVTNDI IRATLKQSRE ARIEILKKML TTIPRPRREI
560 570 580 590 600
SPTAPRLLRT KISPDKIGAL IGPGGKNIRG IQETTGAVIE VDDEGTVLVA
610 620 630 640 650
SSNKESAQEA MRQVEACTAT VQIGKIYDGT VSSIKEFGAF VEILPGRDGL
660 670 680 690 700
VHISEMSGGY ISSLDQVIAV GDAMKVLVID VDEHDRVKLS RRKALEELGE
710 720 730 740 750
EDPLAVEGEG GGDSEGGGDG EDRPRRRRGG SGGGGGGGRG RGPRRSGGGR

DRD
Length:753
Mass (Da):81,118
Last modified:April 29, 2008 - v2
Checksum:iF94F794A31C907EB
GO

Sequence cautioni

The sequence CAD74445 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX294143 Genomic DNA Translation: CAD74445.1 Different initiation.
RefSeqiNP_866904.1, NC_005027.1

Genome annotation databases

EnsemblBacteriaiCAD74445; CAD74445; RB5804
GeneIDi1793865
KEGGirba:RB5804
PATRICifig|243090.15.peg.2795

Similar proteinsi

Entry informationi

Entry nameiPNP_RHOBA
AccessioniPrimary (citable) accession number: Q7UR95
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 29, 2008
Last modified: May 23, 2018
This is version 85 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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