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Q7UR95

- PNP_RHOBA

UniProt

Q7UR95 - PNP_RHOBA

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Protein
Polyribonucleotide nucleotidyltransferase
Gene
pnp, RB5804
Organism
Rhodopirellula baltica (strain SH1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction By similarity.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi488 – 4881Magnesium By similarity
Metal bindingi494 – 4941Magnesium By similarity

GO - Molecular functioni

  1. 3'-5'-exoribonuclease activity Source: InterPro
  2. RNA binding Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: UniProtKB-HAMAP
  4. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. RNA processing Source: InterPro
  2. mRNA catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

Magnesium, Metal-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferase (EC:2.7.7.8)
Alternative name(s):
Polynucleotide phosphorylase
Short name:
PNPase
Gene namesi
Name:pnp
Ordered Locus Names:RB5804
OrganismiRhodopirellula baltica (strain SH1)
Taxonomic identifieri243090 [NCBI]
Taxonomic lineageiBacteriaPlanctomycetesPlanctomycetiaPlanctomycetalesPlanctomycetaceaeRhodopirellula
ProteomesiUP000001025: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 753753Polyribonucleotide nucleotidyltransferaseUniRule annotation
PRO_0000329808Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243090.RB5804.

Structurei

3D structure databases

ProteinModelPortaliQ7UR95.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini555 – 61460KH
Add
BLAST
Domaini624 – 69269S1 motif
Add
BLAST

Sequence similaritiesi

Contains 1 KH domain.
Contains 1 S1 motif domain.

Phylogenomic databases

eggNOGiCOG1185.
HOGENOMiHOG000218326.
KOiK00962.
OrthoDBiEOG6WT8CC.

Family and domain databases

Gene3Di1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPiMF_01595. PNPase.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. RNA-binding_domain_S1.
[Graphical view]
PANTHERiPTHR11252. PTHR11252. 1 hit.
PfamiPF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view]
PIRSFiPIRSF005499. PNPase. 1 hit.
SMARTiSM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF46915. SSF46915. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7UR95-1 [UniParc]FASTAAdd to Basket

« Hide

MSVQKVRVER KIGDSVLSFE TGHIAKQAAG SVLVQYGETV VLVAAASGTP    50
RPGIDFFPLM CDYRERLAAA GKFPGGFLKR EGRPSTKEIL SSRLMDRPIR 100
PLWPAGYKDE VQVQACVIAS DLQNDGDVLA MIGGATALHI SPLPFKGPLG 150
SVRVGKVDGK LVAFPTADQL EQSELDMIVS GSRDMVAMIE GFANEMPEDE 200
MMEAIGFAHD AIREVIDLQE EFYKKVNPEK TPYQSPEDDG LLQRLTDAYY 250
SDFKTAQQTS GKQARAEAVR AVRDRAMADV IPDPNAADAV CVNRFKSVWH 300
DLEEKVVRDL ILAGTRPDGR DHNSLRAIHC ETDLLPRVHG SALFQRGETQ 350
ALITIALGTS RDEQRVDGLQ DEYSKKFMLD YNFPSYSVGE CRPIRGPGRR 400
EIGHGCLAER SVAPVLPSAD DFPYTIRVIS DITESNGSSS MASVCGATLG 450
LMASGVPISN PVAGISVGLV QDGPDNWCLI TDILGTEDHF GDMDFKIAGT 500
QNGITGIQLD LKVTGVTNDI IRATLKQSRE ARIEILKKML TTIPRPRREI 550
SPTAPRLLRT KISPDKIGAL IGPGGKNIRG IQETTGAVIE VDDEGTVLVA 600
SSNKESAQEA MRQVEACTAT VQIGKIYDGT VSSIKEFGAF VEILPGRDGL 650
VHISEMSGGY ISSLDQVIAV GDAMKVLVID VDEHDRVKLS RRKALEELGE 700
EDPLAVEGEG GGDSEGGGDG EDRPRRRRGG SGGGGGGGRG RGPRRSGGGR 750
DRD 753
Length:753
Mass (Da):81,118
Last modified:April 29, 2008 - v2
Checksum:iF94F794A31C907EB
GO

Sequence cautioni

The sequence CAD74445.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX294143 Genomic DNA. Translation: CAD74445.1. Different initiation.
RefSeqiNP_866904.1. NC_005027.1.

Genome annotation databases

EnsemblBacteriaiCAD74445; CAD74445; RB5804.
GeneIDi1793865.
KEGGirba:RB5804.
PATRICi23247033. VBIRhoBal59814_2795.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX294143 Genomic DNA. Translation: CAD74445.1 . Different initiation.
RefSeqi NP_866904.1. NC_005027.1.

3D structure databases

ProteinModelPortali Q7UR95.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243090.RB5804.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD74445 ; CAD74445 ; RB5804 .
GeneIDi 1793865.
KEGGi rba:RB5804.
PATRICi 23247033. VBIRhoBal59814_2795.

Phylogenomic databases

eggNOGi COG1185.
HOGENOMi HOG000218326.
KOi K00962.
OrthoDBi EOG6WT8CC.

Family and domain databases

Gene3Di 1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPi MF_01595. PNPase.
InterProi IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. RNA-binding_domain_S1.
[Graphical view ]
PANTHERi PTHR11252. PTHR11252. 1 hit.
Pfami PF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view ]
PIRSFi PIRSF005499. PNPase. 1 hit.
SMARTi SM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF46915. SSF46915. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
PROSITEi PS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SH1.

Entry informationi

Entry nameiPNP_RHOBA
AccessioniPrimary (citable) accession number: Q7UR95
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 29, 2008
Last modified: May 14, 2014
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi