Reviewed, UniProtKB/Swiss-Prot Q7UQW3 (CYSC_RHOBA)

Names and origin

Protein names

Recommended name:
    Adenylyl-sulfate kinase
    EC=2.7.1.25
Alternative name(s):
    APS kinase
    Adenosine-5'-phosphosulfate kinase
    ATP adenosine-5'-phosphosulfate 3'-phosphotransferase

Gene names

Name:	cysC
Ordered Locus Names:	RB6049

Organism

Rhodopirellula baltica [Complete proteome] [HAMAP]

Taxonomic identifier

117 [NCBI]

Taxonomic lineage

Bacteria › Planctomycetes › Planctomycetacia › Planctomycetales › Planctomycetaceae › Pirellula

Protein attributes

Sequence length	247 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the synthesis of activated sulfate. HAMAP MF_00065
Catalytic activity	ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate. HAMAP MF_00065
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3. HAMAP MF_00065
Sequence similarities	Belongs to the APS kinase family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate assimilation Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP adenylylsulfate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 247	247	Adenylyl-sulfate kinase HAMAP MF_00065		PRO_0000105915
Regions
	Nucleotide binding	55 – 62	8	ATP By similarity
Sites
	Active site	146	1	Phosphoserine intermediate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7UQW3-1 [UniParc]. Last modified October 11, 2005. Version 2. Checksum: 0EEA0EDF8D6A4315	FASTA	247	26,990
	10 20 30 40 50 60 MSQSNSDDSA SSSTQQAGDG QDDVQQNIVW HAHTVSREDR ESKLGQRGVV VWFTGLSGCG 70 80 90 100 110 120 KSTIANELDR LLIDRGATCT LLDGDNVRHG LCAPPSVLKE EHGEDFAGRF GLGFGPTDRE 130 140 150 160 170 180 ENIRRIGAVT ELFASAGVIV LAAFVSPYQR DRDRVRNTIE SSGRAGDFLE VFVDTPLEIC 190 200 210 220 230 240 KQRDPKGLYQ KAIAGEIKNF TGISDPYDAP PSPEIHLKWR EGQTPHDQAS EIIREMEKRG VLGPAKG

References

[1]

"Complete genome sequence of the marine planctomycete Pirellula sp. strain 1." Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W., Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R., Reinhardt R. Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003) [PubMed: 12835416] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX294143 Genomic DNA. Translation: CAD74583.1.
RefSeq	NP_867039.1.
3D structure databases
HSSP	HSSP built from PDB template 1D6J based on UniProtKB Q12657.
ModBase	Search...
Genome annotation databases
GeneID	1790805.
GenomeReviews	Gene locus RB6049 in contig BX119912_GR.
KEGG	rba:RB6049.
NMPDR	fig|243090.1.peg.3379.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7UQW3.
Enzyme and pathway databases
BioCyc	PSP117:RB6049-MON.
BRENDA	2.7.1.25. 280490.
Family and domain databases
HAMAP	MF_00065. [Tree]
InterPro	IPR002891. APS_kinase_C. [Graphical view]
Pfam	PF01583. APS_kinase. 1 hit. [Graphical view]
ProDom	PD002350. APS_kinase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00455. apsK. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSC_RHOBA

Accession

Primary (citable) accession number: Q7UQW3

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	January 20, 2009
This is version 36 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)