Reviewed, UniProtKB/Swiss-Prot Q7UPS1 (MCH_RHOBA)

Names and origin

Protein names

Recommended name:
    Methenyltetrahydromethanopterin cyclohydrolase
    EC=3.5.4.27
Alternative name(s):
    Methenyl-H4MPT cyclohydrolase

Gene names

Name:	mch
Ordered Locus Names:	RB6759

Organism

Rhodopirellula baltica [Complete proteome] [HAMAP]

Taxonomic identifier

117 [NCBI]

Taxonomic lineage

Bacteria › Planctomycetes › Planctomycetacia › Planctomycetales › Planctomycetaceae › Pirellula

Protein attributes

Sequence length	333 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of methenyl-H4MPT+ to 5-formyl-H4MPT By similarity.
Catalytic activity	5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = 5-formyl-5,6,7,8-tetrahydromethanopterin. HAMAP MF_00486
Pathway	One-carbon metabolism; formaldehyde degradation; formate from formaldehyde (H(4)MPT route): step 3/5. HAMAP MF_00486
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the MCH family.

Ontologies

Keywords
Biological process	One-carbon metabolism
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	one-carbon compound metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	methenyltetrahydromethanopterin cyclohydrolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 333	333	Methenyltetrahydromethanopterin cyclohydrolase HAMAP MF_00486		PRO_0000140897

Sequences

	Sequence		Length	Mass (Da)
	Q7UPS1-1 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: BE1E5BD033A92A89	FASTA	333	35,408
	10 20 30 40 50 60 MKSATPDDLP RTGVEPDLSR SASECFESLW NGAIGMRSLP LTIAGARVLD AGVTCSGSLE 70 80 90 100 110 120 AGLGLARLCL GDLANVRYVP ATADDLVGLS VTIQTDHPVL SCLGGQYAGW PVSVADYFAM 130 140 150 160 170 180 ASGPMRCLRG KEAMLEQLHL SRQATDDDFA VGVLESDTLP GEDVIEAMAD ECGVDPSRLC 190 200 210 220 230 240 LAVAPSTSIA GSAQVVSRSV ETALHKLHAL EFDVTRVVSA HGDAPLPPPA KKGDTIGGIG 250 260 270 280 290 300 RTNDAMLYGA RVTLWVDAED DAIDSVASKV PSQSSDDHGR PFAEIFKQYE YDFYQVDPML 310 320 330 FSPAVVTIHS LQSGRTWRHG QISIDVMRKS FGL

References

[1]

"Complete genome sequence of the marine planctomycete Pirellula sp. strain 1." Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W., Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R., Reinhardt R. Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003) [PubMed: 12835416] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX294144 Genomic DNA. Translation: CAD74990.1.
RefSeq	NP_867444.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1792000.
GenomeReviews	Gene locus RB6759 in contig BX119912_GR.
KEGG	rba:RB6759.
NMPDR	fig|243090.1.peg.3784.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7UPS1.
OMA	Q7UPS1. YFAMGSG.
Enzyme and pathway databases
BioCyc	PSP117:RB6759-MON.
BRENDA	3.5.4.27. 280490.
Family and domain databases
HAMAP	MF_00486. [Tree]
InterPro	IPR003209. METHMP_CycHdrlase. [Graphical view]
Pfam	PF02289. MCH. 1 hit. [Graphical view]
TIGRFAMs	TIGR03120. one_C_mch. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MCH_RHOBA

Accession

Primary (citable) accession number: Q7UPS1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 21, 2003
Last sequence update:	October 1, 2003
Last modified:	June 16, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)