Q7UP92 (KGUA_RHOBA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Guanylate kinase
EC=2.7.4.8

Alternative name(s):
GMP kinase

Gene names

Name:	gmk
Ordered Locus Names:	RB7090

Organism

Rhodopirellula baltica (strain SH1)

Taxonomic identifier

243090 [NCBI]

Taxonomic lineage

Bacteria › Planctomycetes › Planctomycetacia › Planctomycetales › Planctomycetaceae › Rhodopirellula

Protein attributes

Sequence length	209 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP MF_00328
Catalytic activity	ATP + GMP = ADP + GDP. HAMAP MF_00328
Subcellular location	Cytoplasm By similarity HAMAP MF_00328.
Sequence similarities	Belongs to the guanylate kinase family. Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	purine nucleotide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW guanylate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 209	209	Guanylate kinase HAMAP MF_00328		PRO_0000170593
Regions
	Domain	16 – 198	183	Guanylate kinase-like
	Nucleotide binding	23 – 30	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7UP92 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: C90C43AC250E21DD	FASTA	209	23,450
	10 20 30 40 50 60 MNDPSCSSAD ETAHPGRLVI ISGPSGAGKS TVVKQLMKRC DVPLQLSVSA TTREPRPGEI 70 80 90 100 110 120 HGQDYFFLSH EEFERRRKLN DFVECKQVFS MGQWYGTLKD QVATGLNAGK WVILEIDVQG 130 140 150 160 170 180 AMAVLDDPHY RPVTIFVHPG SMEELERRLR NRGTESESSL TARLETAAAE MQCLSRYQYE 190 200 IINESVDNAV TEICQILLDQ RKTTPCSKN

References

[1]

"Complete genome sequence of the marine planctomycete Pirellula sp. strain 1." Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W., Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R., Reinhardt R. Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003) [PubMed: 12835416] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SH1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX294145 Genomic DNA. Translation: CAD75170.1.
RefSeq	NP_867623.1. NC_005027.1.
3D structure databases
ProteinModelPortal	Q7UP92.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1791914.
GenomeReviews	Gene locus RB7090 in contig BX119912_GR.
KEGG	rba:RB7090.
NMPDR	fig|243090.1.peg.3963.
PATRIC	23248311. VBIRhoBal59814_3429.
Phylogenomic databases
HOGENOM	HBG671982.
OMA	QMAQGND.
PhylomeDB	Q7UP92.
ProtClustDB	CLSK2759189.
Enzyme and pathway databases
BioCyc	PSP117:RB7090-MONOMER.
Family and domain databases
HAMAP	MF_00328. Guanylate_kinase. [Tree]
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR020590. Guanylate_kinase_CS. IPR017665. Guanylate_kinase_sub. [Graphical view]
KO	K00942.
Pfam	PF00625. Guanylate_kin. 1 hit. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
TIGRFAMs	TIGR03263. Guanyl_kin. 1 hit.
PROSITE	PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KGUA_RHOBA

Accession

Primary (citable) accession number: Q7UP92

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2004
Last sequence update:	October 1, 2003
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program