Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q7UNF9

- SYE_RHOBA

UniProt

Q7UNF9 - SYE_RHOBA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamate--tRNA ligase

Gene

gltX

Organism
Rhodopirellula baltica (strain SH1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).UniRule annotation

Catalytic activityi

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei253 – 2531ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glutamate-tRNA ligase activity Source: UniProtKB-HAMAP
  3. tRNA binding Source: InterPro

GO - Biological processi

  1. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate--tRNA ligaseUniRule annotation (EC:6.1.1.17UniRule annotation)
Alternative name(s):
Glutamyl-tRNA synthetaseUniRule annotation
Short name:
GluRSUniRule annotation
Gene namesi
Name:gltXUniRule annotation
Ordered Locus Names:RB7600
OrganismiRhodopirellula baltica (strain SH1)
Taxonomic identifieri243090 [NCBI]
Taxonomic lineageiBacteriaPlanctomycetesPlanctomycetiaPlanctomycetalesPlanctomycetaceaeRhodopirellula
ProteomesiUP000001025: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 515515Glutamate--tRNA ligasePRO_0000119634Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi243090.RB7600.

Structurei

3D structure databases

ProteinModelPortaliQ7UNF9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi8 – 1811"HIGH" regionAdd
BLAST
Motifi250 – 2545"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000252722.
InParanoidiQ7UNF9.
KOiK01885.
OrthoDBiEOG6DRPF7.

Family and domain databases

Gene3Di1.10.10.350. 1 hit.
1.10.1160.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00022_B. Glu_tRNA_synth_B.
InterProiIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 2 hits.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF48163. SSF48163. 1 hit.
TIGRFAMsiTIGR00464. gltX_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7UNF9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIRTRFAPSP TGYLHIGGVR TALFNWLLAK QAGGQFILRI DDTDAGRNVD
60 70 80 90 100
AALKPILDGF RWLGMDWDEG PDVGGPHGPY FQSERGDQYR AAAEKLLADG
110 120 130 140 150
HAYRDFAKPE ELQTLREEAQ KGGEAFVYDR RWMAEDEATA AKFEAEGRQG
160 170 180 190 200
VVRLKMPREG QCVIQDLIRG EVVVEWASEQ DHVIARADGS PLYHLASVVD
210 220 230 240 250
DHELKITHVV RAAEHLPNTA RQVFIAQSLG YELPIYAHLP YVAEPGGSAK
260 270 280 290 300
LSKRKLDKYK KNRDFAVLLA HGEKIAERCN MQVDADTFNP VLVDFYREIG
310 320 330 340 350
FLPDALLNYL LLLGWSLDGE TEKFTIAEMI EKFTLDRVNK APASFDPAKL
360 370 380 390 400
QSFQGDAFAE LSDEKRTELV RPFAVAAGFV ADGDADETLK AVLAAAGDRL
410 420 430 440 450
KMAGDIVDFD YCFVDDYSVD EKAYEKRLAK ADGAKELLAK LNETLKAATE
460 470 480 490 500
FDAANVETTV KSFCESEGIK IGQIIHALRV ATTGAASGFG MFDTLAVLGK
510
DKVTARIEKT IAGLS
Length:515
Mass (Da):56,844
Last modified:December 15, 2003 - v2
Checksum:iE91E67F990E1E651
GO

Sequence cautioni

The sequence CAD75460.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX294146 Genomic DNA. Translation: CAD75460.1. Different initiation.
RefSeqiNP_867913.1. NC_005027.1.

Genome annotation databases

EnsemblBacteriaiCAD75460; CAD75460; RB7600.
GeneIDi1791060.
KEGGirba:RB7600.
PATRICi23248801. VBIRhoBal59814_3674.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX294146 Genomic DNA. Translation: CAD75460.1 . Different initiation.
RefSeqi NP_867913.1. NC_005027.1.

3D structure databases

ProteinModelPortali Q7UNF9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243090.RB7600.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD75460 ; CAD75460 ; RB7600 .
GeneIDi 1791060.
KEGGi rba:RB7600.
PATRICi 23248801. VBIRhoBal59814_3674.

Phylogenomic databases

eggNOGi COG0008.
HOGENOMi HOG000252722.
InParanoidi Q7UNF9.
KOi K01885.
OrthoDBi EOG6DRPF7.

Family and domain databases

Gene3Di 1.10.10.350. 1 hit.
1.10.1160.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPi MF_00022_B. Glu_tRNA_synth_B.
InterProi IPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF00749. tRNA-synt_1c. 2 hits.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF48163. SSF48163. 1 hit.
TIGRFAMsi TIGR00464. gltX_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SH1.

Entry informationi

Entry nameiSYE_RHOBA
AccessioniPrimary (citable) accession number: Q7UNF9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: December 15, 2003
Last modified: October 29, 2014
This is version 73 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3