ID   Q7ULS5_RHOBA            Unreviewed;      1922 AA.
AC   Q7ULS5;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   27-MAR-2024, entry version 143.
DE   SubName: Full=Probable threonine/tyrosine-specific protein kinase {ECO:0000313|EMBL:CAD76194.1};
DE            EC=2.7.1.- {ECO:0000313|EMBL:CAD76194.1};
GN   OrderedLocusNames=RB9317 {ECO:0000313|EMBL:CAD76194.1};
OS   Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1).
OC   Bacteria; Planctomycetota; Planctomycetia; Pirellulales; Pirellulaceae;
OC   Rhodopirellula.
OX   NCBI_TaxID=243090 {ECO:0000313|EMBL:CAD76194.1, ECO:0000313|Proteomes:UP000001025};
RN   [1] {ECO:0000313|EMBL:CAD76194.1, ECO:0000313|Proteomes:UP000001025}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10527 / NCIMB 13988 / SH1
RC   {ECO:0000313|Proteomes:UP000001025};
RX   PubMed=12835416; DOI=10.1073/pnas.1431443100;
RA   Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W.,
RA   Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R.,
RA   Reinhardt R.;
RT   "Complete genome sequence of the marine planctomycete Pirellula sp. strain
RT   1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001433};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR   EMBL; BX294149; CAD76194.1; -; Genomic_DNA.
DR   RefSeq; NP_868817.1; NC_005027.1.
DR   RefSeq; WP_011122240.1; NC_005027.1.
DR   STRING; 243090.RB9317; -.
DR   EnsemblBacteria; CAD76194; CAD76194; RB9317.
DR   KEGG; rba:RB9317; -.
DR   PATRIC; fig|243090.15.peg.4465; -.
DR   eggNOG; COG0515; Bacteria.
DR   eggNOG; COG2319; Bacteria.
DR   eggNOG; COG3064; Bacteria.
DR   HOGENOM; CLU_239351_0_0_0; -.
DR   InParanoid; Q7ULS5; -.
DR   OrthoDB; 9765809at2; -.
DR   Proteomes; UP000001025; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 5.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR22847:SF637; WD REPEAT DOMAIN 5; 1.
DR   PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF00400; WD40; 8.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00220; S_TKc; 1.
DR   SMART; SM00320; WD40; 16.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 2.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 3.
DR   PROSITE; PS50082; WD_REPEATS_2; 9.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 5.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU10141}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000313|EMBL:CAD76194.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000001025};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000313|EMBL:CAD76194.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   TRANSMEM        676..695
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          285..560
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REPEAT          967..1007
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          1138..1171
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          1189..1231
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          1257..1298
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          1318..1359
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          1408..1449
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          1686..1728
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          1831..1863
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          1884..1915
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1300..1319
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          699..822
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1300..1315
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         314
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   1922 AA;  209657 MW;  5607CC2780037E14 CRC64;
     MTNDKDRQGE PDHGLPEDEN ATENHFSLDE TVEETDSIER NDHRGLSETV DHVDLYATLD
     EGNIIPVAPS NDPDATVADL DKTVEETDQT VQDTDQTIIE NSLTVTDADA TIADASSTVS
     DVNETVAEDA DFDPDETLLE ADQTVSDSNV TVVDETLNDV DATVQESDLT VVETEATVDL
     NATLDETAEK TIPTIHANSK TREDANEATE GTILTDEDIG QTINPRELTS EDVSYWSKLS
     QEFHTGAATV ASFSEFGSAV AGSSLPLRGR QVTTPQESET EASDYRLVRL LGKGGMGNVF
     VARQGSLDRL IAVKIIKPLE EDKRDALRKQ GRLESTENSR RQQFLTEAVI TGDLDHPNIV
     PIHDVAVTGE NTLFYAMKRV VGTPWNKIIG EKSRDENLEI LIKVADAIAF AHTRGIIHRD
     IKPENVMLGD FGVVMVMDWG IALAMPQFEK LNSITPAKGL GGTPSFMAPE MATGPLEAIG
     PAADIYLLGA TLFMIVTGKA PHHAKNVREC LRAVATNEIR EVDPRHEGEL LNIARKAMAT
     RIEDRYSSVI EFQEAIREYR SHSESISLAA RATDDLNKAE QTLSYTLFSR ATFGFEEALH
     LWDGNQTARE GIARARLAHA SAAHDNKDFD LGLSLLKPDG LLLHDSPEHE TLATKLEQSI
     QDRKARESRF KFLKRAVAAM LLFIFVGGAF ALVTINAKEQ EARQFAENAE LRRKEAEEQR
     KIAEGATKQA RNNLQLAEDN LDRALAGEEL AKKNAEKADA NAKEAVENAK LAVKNAKEAE
     RNEKRAELNA EEARISANAA LVAQEKAEIA RAEAEYESYV SQIGLAKARV DRNEFSDARR
     ILSELTEDYR QRFPNDPLPW ELRWLSATVH QSKTVASLPV IADQLLLAQA PTSESRRGLI
     VQDNGKIATF SLANTGRLAM AEAWSDPNGG FVTAAAMNES GEQVALGMLD GKIEIWNEDL
     SVRVSRLPAH DGPVSDLGFA DSNTLVSSST DRTIRLWNLN SRNESDIPAY SEHWHVGPVT
     QVAAVRDGET VWVSAAVNDS ARGRVAVWNI GVNRDGAGTR VGRFMQHDSE VSALSAWMED
     DSPVFASGDT DGNVFVWGQG DLVDADPKKS IESAVQDLAS VDASNTRIDE PKASAEPAPI
     HRGGVQAIRY DKTIDRLITA GKDYVVRTWK LADIPHEAEL GPWARERSLR GHGGAVKAAV
     FVPASGGDVL SLGDDQTLRY WESETGRLDS RLEEDLTSAR ASSNQDLAAD GLDAFETAAH
     DDEIWSARFS PDGTKVVTSS RDHTARVLSI DPGTSRFDTR LTISSDQSSS EEDGGTLEEG
     SAFGAMSMRM DPVHRRLFLG NADATVRIWD IDRGTELGSV RGTGLNDVLA VSKDGSLLAT
     GSSSAESDVL VWKLDPSKQV SPRLLHRLNG HEESVAALAI SPDSQWLFSG DRAGRGRVWD
     LQTGEPVGEP IDDLLGFRIN TASFAGDSKS VWVGSDNQSL MRWRWSDRTW VDRHDTNGFV
     MNLVVSPDGR QAITIDQSKR TDRTISNVTW WDLSNGKQQR LLSETFSNDQ TSAFGGRPNF
     GGAAFSTDGR LARLVVTPAG GRSSRVETWD LSGNVGTAKR VAAVELPERI GECTAVASLQ
     GARFVTMHGN AAFRWDGDSN THLMSYRAHG AVTRATFAGG DRRVITASRS VKVWDAESGK
     TVGKLESPHE GTVRAIAISP KETFRLVTGG DDSRVRVWDF DEETGSFQSV RQWNDPILQG
     GIASLDFSPD GSCLLATTNQ GAATLMRMDG KATLNLVADP SLGKLNVGRF SNDSRWVAVG
     GSDNVARMWD VSKWFKNPRL GGADMKAPIQ LIGHAEPIAD LAVLSNPLRL FTASEDRSVR
     VWDPIAQGAN HDEQARFGRE LLELRGHKNA LSALDLTDKG DLMMTASEDG TVRLWPAMVD
     PD
//