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Q7UK37 (Q7UK37_RHOBA) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Lysine--tRNA ligase HAMAP-Rule MF_00252 RuleBase RU000336
EC=6.1.1.6 HAMAP-Rule MF_00252 RuleBase RU000336
Alternative name(s):
Lysyl-tRNA synthetase HAMAP-Rule MF_00252
Gene names
Name:lysS HAMAP-Rule MF_00252 EMBL CAD77044.1
Ordered Locus Names:RB10883
OrganismRhodopirellula baltica (strain SH1) [Reference proteome] [HAMAP]
Taxonomic identifier243090 [NCBI]
Taxonomic lineageBacteria › Planctomycetes › Planctomycetia › Planctomycetales › Planctomycetaceae › Rhodopirellula ›

Protein attributes

Sequence length546 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP-Rule MF_00252 SAAS SAAS002313

Cofactor

Binds 3 magnesium ions per subunit By similarity. HAMAP-Rule MF_00252

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00252 SAAS SAAS002313

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00252.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00252 RuleBase RU003746

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding4581Magnesium 1 By similarity HAMAP-Rule MF_00252
Metal binding4651Magnesium 1 By similarity HAMAP-Rule MF_00252
Metal binding4651Magnesium 2 By similarity HAMAP-Rule MF_00252

Sequences

Sequence LengthMass (Da)Tools
Q7UK37 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 6AF43ED9BBBAED60

FASTA54661,659
        10         20         30         40         50         60 
MNEAANSQSS ARLIVSTFAS AFAVTDTPSN ADDLDLTDPH AARRHKLEEI TAKGIDPWGQ 

        70         80         90        100        110        120 
RFDDRLLVSE CRDRIPQIQW QQKDGETIAL PDVESDEVDY RQWKADNGPG EEIGPIVRVA 

       130        140        150        160        170        180 
GRILLARPTG KLIFMNIRDW TGDIQIFVGK KQVGDENFDL AKLFDLGDLI GVQGRLGRTN 

       190        200        210        220        230        240 
TGELTVFAEE LFLLTKMLEV PPEKHAGMTN QDLRQRMRYA DLAFNDGVMQ TFLDRTKIIK 

       250        260        270        280        290        300 
SIRSTLDDQG FCEVEGPTLH TVPGGAAARP FETHHNALDM QLTMRIALEL HLKRLMVGGM 

       310        320        330        340        350        360 
ERVYELGRVY RNEGLSPRHN PEFTMLETYQ AYGNYESMMD LTEKIICDAI EKIGGGFKRE 

       370        380        390        400        410        420 
YNGTMLDFTP PFQRATYAEL FQKATGIDPA NEDAVKEYAK GLKLTIEGKH PDVIRNEIFE 

       430        440        450        460        470        480 
EKVEDSLQGP IFVTDYPASI CPLTKRKKDN PEIAERFEMF ICGMELANAY TELNDPDLQE 

       490        500        510        520        530        540 
ELFKTQLEGQ DDEDSMAKMD HDFVRALRYG MPPAGGLGIG IDRLVMVLTN QKSIRDVILF 


PVLRPE

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References

[1]"Complete genome sequence of the marine planctomycete Pirellula sp. strain 1."
Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W., Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R., Reinhardt R.
Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SH1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX294152 Genomic DNA. Translation: CAD77044.1.
RefSeqNP_869666.1. NC_005027.1.

3D structure databases

ProteinModelPortalQ7UK37.
ModBaseSearch...

Protein-protein interaction databases

STRING243090.RB10883.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD77044; CAD77044; RB10883.
GeneID1796815.
KEGGrba:RB10883.
PATRIC23251995. VBIRhoBal59814_5254.

Phylogenomic databases

HOGENOMHOG000236578.
KOK04567.
OMAEHKLEQP.
ProtClustDBCLSK2759681.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00252. Lys_tRNA_synth_class2.
InterProIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR002313. Lys-tRNA-ligase_II.
IPR018149. Lys-tRNA-synth_II_C.
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA-helicase.
[Graphical view]
PANTHERPTHR22594. PTHR22594. 1 hit.
PTHR22594:SF4. PTHR22594:SF4. 1 hit.
PfamPF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti. 1 hit.
[Graphical view]
PRINTSPR00982. TRNASYNTHLYS.
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMsTIGR00499. lysS_bact. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ7UK37_RHOBA
AccessionPrimary (citable) accession number: Q7UK37
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: May 29, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info