Reviewed, UniProtKB/Swiss-Prot Q7UJK0 (MSRA1_RHOBA)

Names and origin

Protein names

Recommended name:
    Peptide methionine sulfoxide reductase msrA 1
      Short name=Protein-methionine-S-oxide reductase 1
    EC=1.8.4.11
Alternative name(s):
    Peptide-methionine (S)-S-oxide reductase 1
      Short name=Peptide Met(O) reductase 1

Gene names

Name:	msrA1
Ordered Locus Names:	RB11847

Organism

Rhodopirellula baltica [Complete proteome] [HAMAP]

Taxonomic identifier

117 [NCBI]

Taxonomic lineage

Bacteria › Planctomycetes › Planctomycetacia › Planctomycetales › Planctomycetaceae › Pirellula

Protein attributes

Sequence length	192 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity.
Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the msrA Met sulfoxide reductase family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 192	192	Peptide methionine sulfoxide reductase msrA 1 HAMAP MF_01401		PRO_0000232664
Sites
	Active site	25	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7UJK0-1 [UniParc]. Last modified April 18, 2006. Version 2. Checksum: B01D9AFCE2ED80D3	FASTA	192	21,782
	10 20 30 40 50 60 MPFDSEIVEV KTRPGEEVAT LAGGCFWCTE AVFERMEGVN DVVSGYIGGK IKNPNYKQVC 70 80 90 100 110 120 GKMTGHAEAV QIYYDPSKTN FEELLKVFFK THDPTTLNRQ GADGGPQYRS SIFVHNDEQR 130 140 150 160 170 180 EIAKKTMEKL GEEYRDPIVT LIEPATKFYV AEEYHQDYYR RNPNAGYCQA VVAAKVRKFN 190 RNFGDKIKGS GK

References

[1]

"Complete genome sequence of the marine planctomycete Pirellula sp. strain 1." Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W., Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R., Reinhardt R. Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003) [PubMed: 12835416] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX294154 Genomic DNA. Translation: CAD77258.1. Different initiation.
RefSeq	NP_870183.1.
3D structure databases
HSSP	HSSP built from PDB template 1FF3 based on UniProtKB P27110.
ModBase	Search...
Genome annotation databases
GeneID	1794193.
GenomeReviews	Gene locus RB11847 in contig BX119912_GR.
KEGG	rba:RB11847.
NMPDR	fig|243090.1.peg.6523.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7UJK0.
Enzyme and pathway databases
BioCyc	PSP117:RB11847-MON.
BRENDA	1.8.4.11. 280490.
Family and domain databases
HAMAP	MF_01401. [Tree]
InterPro	IPR002569. MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
ProDom	PD003489. PMSR. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00401. msrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MSRA1_RHOBA

Accession

Primary (citable) accession number: Q7UJK0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 18, 2006
Last sequence update:	April 18, 2006
Last modified:	January 20, 2009
This is version 28 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)