ID   Q7UIV4_RHOBA            Unreviewed;       758 AA.
AC   Q7UIV4;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   27-MAR-2024, entry version 116.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   OrderedLocusNames=RB12310 {ECO:0000313|EMBL:CAD77508.1};
OS   Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1).
OC   Bacteria; Planctomycetota; Planctomycetia; Pirellulales; Pirellulaceae;
OC   Rhodopirellula.
OX   NCBI_TaxID=243090 {ECO:0000313|EMBL:CAD77508.1, ECO:0000313|Proteomes:UP000001025};
RN   [1] {ECO:0000313|EMBL:CAD77508.1, ECO:0000313|Proteomes:UP000001025}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10527 / NCIMB 13988 / SH1
RC   {ECO:0000313|Proteomes:UP000001025};
RX   PubMed=12835416; DOI=10.1073/pnas.1431443100;
RA   Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W.,
RA   Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R.,
RA   Reinhardt R.;
RT   "Complete genome sequence of the marine planctomycete Pirellula sp. strain
RT   1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001433};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR   EMBL; BX294154; CAD77508.1; -; Genomic_DNA.
DR   RefSeq; NP_870431.1; NC_005027.1.
DR   RefSeq; WP_011123669.1; NC_005027.1.
DR   AlphaFoldDB; Q7UIV4; -.
DR   STRING; 243090.RB12310; -.
DR   EnsemblBacteria; CAD77508; CAD77508; RB12310.
DR   KEGG; rba:RB12310; -.
DR   PATRIC; fig|243090.15.peg.5943; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG0515; Bacteria.
DR   HOGENOM; CLU_007799_1_0_0; -.
DR   InParanoid; Q7UIV4; -.
DR   OrthoDB; 258731at2; -.
DR   Proteomes; UP000001025; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR43289; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED; 1.
DR   PANTHER; PTHR43289:SF6; SERINE_THREONINE-PROTEIN KINASE NEKL-3; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:CAD77508.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001025};
KW   Transferase {ECO:0000313|EMBL:CAD77508.1}.
FT   DOMAIN          89..387
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          315..349
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          435..472
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   758 AA;  84665 MW;  2CD61B4DD43245A0 CRC64;
     MSASMTVASE KTIFFHALEI DSLEQRTEYV RQACKNNTQL LSAVSALLRE NDREVNPIDR
     PVAAEMLPTM MSGELTDPRF SPGAMVGPYQ LMERIGEGGF GWVFVAQQRS PVQRRAALKI
     IKPGMESREV IARFEAERQA IALMDHPNIA RVFDAGVTET AQPYFVMELV RGVPLTDFCN
     SNRLRISDRL QLFVTICHAV QHAHQKGIIH RDLKPSNILV TLQDGRPLAK VIDFGVAKAI
     GQSLTVKTIY TRFTSMVGTP AYMSPEQAAM STDDVDTRSD IYSLGVLLYE LLTGSTPFAP
     DRLQTAGFDE LRRIIREEEP PRPSTRLSTL NSEESRTSDV ERLGPPTTPS TAMKRDLDWI
     VMKALHKDRN RRYSTAGALA EDILRFLQDQ PVEARPPSSW YRFTTFARRN KVAISTFSLV
     AIALIIGTAT SLWQAREAIR ERDEKELALA EAREAEVAAN AARSELENFN DRLNSTTVLL
     AAGRANADAQ RWPDAYEAYS EATQVLPKSF LVWLERGGLN AKLGRWESSA NDFVKAVEIG
     FPIEQAELNG VPQILLYAGR SDAYETLLQE LRQSDTEVPF AVSARGQLVG SLSPNRAAEL
     ADQMEQMLSK TFDSDVSSGP LNKRQRYAKI YYGVNLYVAG LAHLKAGDYQ QALHRLEETN
     HANWFGRGIA KPLIAIAHHR MGNADDAVQS FEESQVFLDR MLDESIERSK GSPSMPWIDW
     IEFLIHHREA SIVVKGHTPA ADPRFQQLQV FADAAIDG
//