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Q7UIA4

- PYRF_RHOBA

UniProt

Q7UIA4 - PYRF_RHOBA

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Protein

Orotidine 5'-phosphate decarboxylase

Gene

pyrF

Organism
Rhodopirellula baltica (strain SH1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Orotidine 5'-phosphate = UMP + CO2.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei105 – 1051Proton donorUniRule annotation

GO - Molecular functioni

  1. orotidine-5'-phosphate decarboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
  2. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Pyrimidine biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00070; UER00120.

Names & Taxonomyi

Protein namesi
Recommended name:
Orotidine 5'-phosphate decarboxylaseUniRule annotation (EC:4.1.1.23UniRule annotation)
Alternative name(s):
OMP decarboxylaseUniRule annotation
Short name:
OMPDCaseUniRule annotation
Short name:
OMPdecaseUniRule annotation
Gene namesi
Name:pyrFUniRule annotation
Ordered Locus Names:RB12661
OrganismiRhodopirellula baltica (strain SH1)
Taxonomic identifieri243090 [NCBI]
Taxonomic lineageiBacteriaPlanctomycetesPlanctomycetiaPlanctomycetalesPlanctomycetaceaeRhodopirellula
ProteomesiUP000001025: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 302302Orotidine 5'-phosphate decarboxylasePRO_0000227023Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243090.RB12661.

Structurei

3D structure databases

ProteinModelPortaliQ7UIA4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the OMP decarboxylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0284.
HOGENOMiHOG000245747.
InParanoidiQ7UIA4.
KOiK01591.
OMAiCRTSNAG.
OrthoDBiEOG6DZF33.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_01215. OMPdecase_type2.
InterProiIPR013785. Aldolase_TIM.
IPR018089. OMPdecase_AS.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTiSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
TIGRFAMsiTIGR02127. pyrF_sub2. 1 hit.
PROSITEiPS00156. OMPDECASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7UIA4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMTFATQLNA AILRTGSVTC VGLDPRLEQL PKPLRDSVSE KRKDSVAAAY
60 70 80 90 100
TQFCCEIIDA VAGLVPCVKP QAAFFEQLGP AGMVSLGEVI SHANQAGLIV
110 120 130 140 150
ITDGKRNDIG STATAYADAY LGSAEPDRSP WGSDALTVSP YLGRDSLEPF
160 170 180 190 200
VEVCDRRAAG IFVLVKTSNP GGGYLQDLSV DGKTIYQSVA ELVTELNKSR
210 220 230 240 250
LDADGYGPVG AVVGATYPEQ LVELRKAMPH SILLVPGFGA QGGSADDVRA
260 270 280 290 300
AMDANGAGAV VNSSRHIVFA HKREEFSVAA DESNWQDAVR AATIQMNEQL

KG
Length:302
Mass (Da):31,904
Last modified:October 1, 2003 - v1
Checksum:iF5A7B44C039B7C57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX294155 Genomic DNA. Translation: CAD77710.1.
RefSeqiNP_870633.1. NC_005027.1.

Genome annotation databases

EnsemblBacteriaiCAD77710; CAD77710; RB12661.
GeneIDi1790129.
KEGGirba:RB12661.
PATRICi23253825. VBIRhoBal59814_6141.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX294155 Genomic DNA. Translation: CAD77710.1 .
RefSeqi NP_870633.1. NC_005027.1.

3D structure databases

ProteinModelPortali Q7UIA4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243090.RB12661.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD77710 ; CAD77710 ; RB12661 .
GeneIDi 1790129.
KEGGi rba:RB12661.
PATRICi 23253825. VBIRhoBal59814_6141.

Phylogenomic databases

eggNOGi COG0284.
HOGENOMi HOG000245747.
InParanoidi Q7UIA4.
KOi K01591.
OMAi CRTSNAG.
OrthoDBi EOG6DZF33.

Enzyme and pathway databases

UniPathwayi UPA00070 ; UER00120 .

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_01215. OMPdecase_type2.
InterProi IPR013785. Aldolase_TIM.
IPR018089. OMPdecase_AS.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00215. OMPdecase. 1 hit.
[Graphical view ]
SMARTi SM00934. OMPdecase. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
TIGRFAMsi TIGR02127. pyrF_sub2. 1 hit.
PROSITEi PS00156. OMPDECASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SH1.

Entry informationi

Entry nameiPYRF_RHOBA
AccessioniPrimary (citable) accession number: Q7UIA4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: October 1, 2003
Last modified: October 29, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3