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Q7UI59

- PUR5_RHOBA

UniProt

Q7UI59 - PUR5_RHOBA

Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Rhodopirellula baltica (strain SH1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 2 (28 Nov 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Purine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00074; UER00129.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
    Alternative name(s):
    AIR synthaseUniRule annotation
    AIRSUniRule annotation
    Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
    Gene namesi
    Name:purMUniRule annotation
    Ordered Locus Names:RB12745
    OrganismiRhodopirellula baltica (strain SH1)
    Taxonomic identifieri243090 [NCBI]
    Taxonomic lineageiBacteriaPlanctomycetesPlanctomycetiaPlanctomycetalesPlanctomycetaceaeRhodopirellula
    ProteomesiUP000001025: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 359359Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000148240Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243090.RB12745.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7UI59.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AIR synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0150.
    HOGENOMiHOG000229090.
    KOiK01933.
    OrthoDBiEOG61CM1V.

    Family and domain databases

    Gene3Di3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPiMF_00741_B. AIRS_B.
    InterProiIPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view]
    PfamiPF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsiTIGR00878. purM. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q7UI59-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASTYKDAGV DLDVYAESMS RLPRLMHRTF SPRVMPSDGG FAGLFRLDFP    50
    GKLFARNYEE PVLVSGTDGV GTKLKIAQTM NQHETVGIDL VAMCVNDLIC 100
    TGAEPLFFLD YVAMGRDDPA RLERIVQGIS DGCVDGDLAL LGGETAIMPD 150
    MYGTDDYDLA GFAVGVVERK RLVDGHLIAP GDVVLGLQAS GLHSNGFSLV 200
    RKIIADHGHQ WSDVIDELNQ DTKTPETLAQ VCLRPTKIYV SAIRSIQSHY 250
    RVKQVLHGIA HITGGGIEEN LDRILPPGVN AEIDPNAWTP NPIFQWLQQT 300
    GDVATSEMRR VFNMGIGMAV VVNEYYAASV ASQVAKAGIE CSPIGRIVEG 350
    SSKVVYKEA 359
    Length:359
    Mass (Da):38,937
    Last modified:November 28, 2003 - v2
    Checksum:iE8BD8C886B89572C
    GO

    Sequence cautioni

    The sequence CAD77755.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX294155 Genomic DNA. Translation: CAD77755.1. Different initiation.
    RefSeqiNP_870678.1. NC_005027.1.

    Genome annotation databases

    EnsemblBacteriaiCAD77755; CAD77755; RB12745.
    GeneIDi1792852.
    KEGGirba:RB12745.
    PATRICi23253901. VBIRhoBal59814_6179.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX294155 Genomic DNA. Translation: CAD77755.1 . Different initiation.
    RefSeqi NP_870678.1. NC_005027.1.

    3D structure databases

    ProteinModelPortali Q7UI59.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243090.RB12745.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAD77755 ; CAD77755 ; RB12745 .
    GeneIDi 1792852.
    KEGGi rba:RB12745.
    PATRICi 23253901. VBIRhoBal59814_6179.

    Phylogenomic databases

    eggNOGi COG0150.
    HOGENOMi HOG000229090.
    KOi K01933.
    OrthoDBi EOG61CM1V.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00129 .

    Family and domain databases

    Gene3Di 3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPi MF_00741_B. AIRS_B.
    InterProi IPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view ]
    Pfami PF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsi TIGR00878. purM. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SH1.

    Entry informationi

    Entry nameiPUR5_RHOBA
    AccessioniPrimary (citable) accession number: Q7UI59
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 28, 2003
    Last sequence update: November 28, 2003
    Last modified: October 1, 2014
    This is version 70 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3