ATP synthase subunit alpha 1 - Rhodopirellula baltica (strain SH1)

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Q7UH05 (ATPA1_RHOBA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 66. History...

Clusters with 100%, 90%, 50% identity |

Documents (1) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
ATP synthase subunit alpha 1
EC=3.6.3.14

Alternative name(s):
ATP synthase F1 sector subunit alpha 1
F-ATPase subunit alpha 1

Gene names

Name:	atpA1
Ordered Locus Names:	RB4916

Organism

Rhodopirellula baltica (strain SH1)

Taxonomic identifier

243090 [NCBI]

Taxonomic lineage

Bacteria › Planctomycetes › Planctomycetacia › Planctomycetales › Planctomycetaceae › Rhodopirellula

Protein attributes

Sequence length	504 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit By similarity. HAMAP MF_01346
Catalytic activity	ATP + H₂O + H⁺(In) = ADP + phosphate + H⁺(Out). HAMAP MF_01346
Subunit structure	F-type ATPases have 2 components, CF₁ - the catalytic core - and CF₀ - the membrane proton channel. CF₁ has five subunits: alpha₃, beta₃, gamma₁, delta₁, epsilon₁. CF₀ has three main subunits: a₁, b₂ and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF₁ is attached to CF₀ by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_01346.
Sequence similarities	Belongs to the ATPase alpha/beta chains family.
Sequence caution	The sequence CAD78174.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(1) Cell inner membrane Cell membrane Membrane
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell proton-transporting ATP synthase complex, catalytic core F(1) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 504

504

ATP synthase subunit alpha 1 HAMAP MF_01346

PRO_0000238341

Regions

Nucleotide binding

172 – 179

ATP By similarity

Sites

Site

365

Required for activity By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

Q7UH05 [UniParc].

Last modified May 30, 2006. Version 2.
Checksum: AFA748D4CC3FC9FE
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FASTA

504

54,920

        10         20         30         40         50         60 
MTTYSETLET AAQQFDQAVK SQPSQLTVTE IGTVEEVQRG IARVHGLPHV QVDEVLRFAG 

        70         80         90        100        110        120 
GHLGYAFNLD PDQVGCVLLD SSDQITAGSR VERMHSVLDT PVGDQLLGRV VDPVGRPLDG 

       130        140        150        160        170        180 
GRSLDDLPRE PCERDAPPIM QRAPVTVPLQ SGLKVVDAMI PIGRGQRQLL LGDRQTGKTA 

       190        200        210        220        230        240 
IAIDTIINQL GRDVICIYCS IGQRSTGVAR VIENLRRHDA LDHTIVVIGA DDAPPGLQFL 

       250        260        270        280        290        300 
APYAATTMGE HFMRQGRDVM IVYDDLTSHA RAYRHLSLLL RRPPGREAFP GDIFYVHSRL 

       310        320        330        340        350        360 
LERSTHLIQS AGGGSLTALP IIETEAQNVS AYIPTNLISI TDGQIYLSPT LFRKGVLPAI 

       370        380        390        400        410        420 
DVGRSVSRVG GKTQLPAYRV VAGDLRLTYS QFEELERFAR FSSQLDEDTR ATLDRGRLIR 

       430        440        450        460        470        480 
EILKQTQFQP LTLPQQIASL IAVTNGVLDG VPVDQLPTIE RAIQDAVTSQ ANDLCAQMQS 

       490        500 
GKKLDKQQVG QIANIAAGAV HAHA

« Hide

References

[1]

"Complete genome sequence of the marine planctomycete Pirellula sp. strain 1."
Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W., Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R., Reinhardt R.
Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003) [PubMed: 12835416] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SH1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX294141 Genomic DNA. Translation: CAD78174.1. Different initiation.
RefSeq	NP_866393.2. NC_005027.1.
3D structure databases
ProteinModelPortal	Q7UH05.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1795580.
GenomeReviews	Gene locus RB4916 in contig BX119912_GR.
KEGG	rba:RB4916.
NMPDR	fig\|243090.1.peg.2733.
PATRIC	23246119. VBIRhoBal59814_2340.
Phylogenomic databases
HOGENOM	HBG565875.
PhylomeDB	Q7UH05.
ProtClustDB	PRK09281.
Enzyme and pathway databases
BioCyc	PSP117:RB4916-MONOMER.
Family and domain databases
HAMAP	MF_01346. ATP_synth_alpha_bact. [Tree]
InterPro	IPR017710. Alt_ATPase_F1-cplx_asu. IPR020003. ATPase_a/bsu_AS. IPR005294. ATPase_F1-cplx_asu. IPR018118. ATPase_F1/A1-cplx_a/bsu_N. IPR023366. ATPase_F1/A1-cplx_a_su_N. IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C. IPR004100. ATPase_F1/V1/A1-cplx_a/bsu_N. IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd. [Graphical view]
Gene3D	G3DSA:2.40.30.20. G3DSA:2.40.30.20. 1 hit.
KO	K02111.
PANTHER	PTHR15184:SF3. ATPase_F1_a. 1 hit.
Pfam	PF00006. ATP-synt_ab. 1 hit. PF00306. ATP-synt_ab_C. 1 hit. PF02874. ATP-synt_ab_N. 1 hit. [Graphical view]
SUPFAM	SSF47917. ATPase_a/b_C. 1 hit. SSF50615. ATPase_a/b_N. 1 hit.
TIGRFAMs	TIGR03324. Alt_F1F0_F1_al. 1 hit. TIGR00962. AtpA. 1 hit.
PROSITE	PS00152. ATPASE_ALPHA_BETA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATPA1_RHOBA

Accession

Primary (citable) accession number: Q7UH05

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	May 30, 2006
Last modified:	January 25, 2012
This is version 66 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sites

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents