Q7UFG7 (GPMI_RHOBA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=iPGM
EC=5.4.2.1

Gene names

Name:	gpmI
Synonyms:	pgm
Ordered Locus Names:	RB8562

Organism

Rhodopirellula baltica (strain SH1) [Reference proteome] [HAMAP]

Taxonomic identifier

243090 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Planctomycetes › Planctomycetia › Planctomycetales › Planctomycetaceae › Rhodopirellula › Rhodopirellula baltica

Protein attributes

Sequence length	543 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP-Rule MF_01038
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP-Rule MF_01038
Cofactor	Binds 2 manganese ions per subunit By similarity.
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP-Rule MF_01038
Subunit structure	Monomer By similarity.
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family.

Ontologies

Keywords
Biological process	Glycolysis
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 543	543	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP-Rule MF_01038		PRO_0000212195
Sites
	Active site	73	1	Phosphoserine intermediate By similarity
	Metal binding	20	1	Manganese 2 By similarity
	Metal binding	73	1	Manganese 2 By similarity
	Metal binding	428	1	Manganese 1 By similarity
	Metal binding	432	1	Manganese 1 By similarity
	Metal binding	469	1	Manganese 2 By similarity
	Metal binding	470	1	Manganese 2 By similarity
	Metal binding	488	1	Manganese 1 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7UFG7 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: D2AB2967D098CC45	FASTA	543	59,011
	10 20 30 40 50 60 MVLTFMTATR RRPVVLIVRD GWGQNPDPKW NESNAVHLAN TPVDDKLTQE YPSVLIHTSG 70 80 90 100 110 120 EDVGLPAGVM GNSEVGHQNI GAGRIVDQEV MRITRAIRDD SFFSNPVVTG AIDHVKKSGG 130 140 150 160 170 180 RLHLLGLMSD GRVHSDLQHG IAVIDLAKRN GLTGDQLAIH AITDGRDTSP RGGLKFVSQL 190 200 210 220 230 240 TDHCEASGVG VVASVIGRFY AMDRDLRWER VEAAYNLMTQ GTGQTFPSAS AAIESYYANP 250 260 270 280 290 300 TESSRDGDEF ITASSIVPEG GSPITVQPGD AVLFMNYRGD RTREITKAFT FDDAAWKDIP 310 320 330 340 350 360 GGGFDRGKKI DNLYFATMTG YETGLPVKVI FEKPAKMPNI LGEYVASKGL HQFRCAETEK 370 380 390 400 410 420 YPHVTFFFND YRDNPFEEEE WGMAPSPRDV STYDQKPEMS AEDITEKVLK QIKSGKCDMI 430 440 450 460 470 480 IVNYANGDMV GHTGVLEAAI KAVEKVDACV GRVVDATLAA GGSLVVTADH GNCEQMIDPE 490 500 510 520 530 540 TGGPHTAHTT YQVPLIVVDP EFVGKPLREG GRLADIAPTV LALMGLEVPP EMTGRPLMET QTA

References

[1]

"Complete genome sequence of the marine planctomycete Pirellula sp. strain 1." Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W., Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R., Reinhardt R. Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SH1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX294147 Genomic DNA. Translation: CAD78715.1.
RefSeq	NP_868437.1. NC_005027.1.
3D structure databases
ProteinModelPortal	Q7UFG7.
ModBase	Search...
Protein-protein interaction databases
STRING	243090.RB8562.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAD78715; CAD78715; RB8562.
GeneID	1792126.
KEGG	rba:RB8562.
PATRIC	23249695. VBIRhoBal59814_4115.
Phylogenomic databases
eggNOG	COG0696.
HOGENOM	HOG000223664.
KO	K15633.
OMA	NAEQMTD.
ProtClustDB	PRK05434.
Enzyme and pathway databases
UniPathway	UPA00109; UER00186.
Family and domain databases
Gene3D	3.40.1450.10. 1 hit. 3.40.720.10. 2 hits.
HAMAP	MF_01038. GpmI.
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR011258. BPG-indep_PGM_N. IPR006124. Metalloenzyme. IPR005995. Pgm_bpd_ind. [Graphical view]
Pfam	PF06415. iPGM_N. 1 hit. PF01676. Metalloenzyme. 1 hit. [Graphical view]
PIRSF	PIRSF001492. IPGAM. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit. SSF64158. BPG-indep_PGM_N. 1 hit.
TIGRFAMs	TIGR01307. pgm_bpd_ind. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GPMI_RHOBA

Accession

Primary (citable) accession number: Q7UFG7

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2004
Last sequence update:	October 1, 2003
Last modified:	May 1, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program