Q7U7H6 (COMB_SYNPX) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	SYNW1007

Organism

Synechococcus sp. (strain WH8102) [Complete proteome] [HAMAP]

Taxonomic identifier

84588 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	242 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 242	242	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081475

Sequences

	Sequence		Length	Mass (Da)
	Q7U7H6 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 73A0522369FBD9CF	FASTA	242	25,837
	10 20 30 40 50 60 MQIFYFHVPA EMPADASPDA AVVIDVLRAT TTIAWALHHG AEAVQAFADL EDLRAAAEAW 70 80 90 100 110 120 PADQRLLLGE RGGQTLAGFD LGNSPVAVVP ATVSGKRLFM STTNGTRALD RVRQVPLLVT 130 140 150 160 170 180 AALPNREAVA QRLLKESPET VAIVGSGWEG TYSLEDSLAA GALAARLQEL SQAVTLANDE 190 200 210 220 230 240 ATAATALWQQ WRHDPEACLR TASHGQRLIR LGDHDDDFRC CAGLDQLSVV PTQQSPGVLQ AI

References

[1]

"The genome of a motile marine Synechococcus." Palenik B., Brahamsha B., Larimer F.W., Land M.L., Hauser L., Chain P., Lamerdin J.E., Regala W., Allen E.E., McCarren J., Paulsen I.T., Dufresne A., Partensky F., Webb E.A., Waterbury J. Nature 424:1037-1042(2003) [PubMed: 12917641] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WH8102.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX569691 Genomic DNA. Translation: CAE07522.1.
RefSeq	NP_897100.1. NC_005070.1.
3D structure databases
ProteinModelPortal	Q7U7H6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7U7H6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1731886.
GenomeReviews	Gene locus SYNW1007 in contig BX548020_GR.
KEGG	syw:SYNW1007.
PATRIC	23833487. VBISynSp27240_1048.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2045.
HOGENOM	HBG633644.
OMA	GWEGAYS.
PhylomeDB	Q7U7H6.
ProtClustDB	PRK00886.
Enzyme and pathway databases
BioCyc	SSP84588:SYNW1007OR0035-MONOMER.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_SYNPX

Accession

Primary (citable) accession number: Q7U7H6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 2, 2004
Last sequence update:	October 1, 2003
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program