Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Synechococcus sp. (strain WH8102)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:SYNW1195
OrganismiSynechococcus sp. (strain WH8102)
Taxonomic identifieri84588 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeSynechococcus
Proteomesi
  • UP000001422 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000830691 – 338Methionyl-tRNA formyltransferaseAdd BLAST338

Interactioni

Protein-protein interaction databases

STRINGi84588.SYNW1195

Structurei

3D structure databases

ProteinModelPortaliQ7U6Z1
SMRiQ7U6Z1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni110 – 113Tetrahydrofolate (THF) bindingUniRule annotation4

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CAE Bacteria
COG0223 LUCA
HOGENOMiHOG000261177
KOiK00604
OMAiLRIVFMG
OrthoDBiPOG091H01YM

Family and domain databases

HAMAPiMF_00182 Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794 Fmt
IPR005793 Formyl_trans_C
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR011034 Formyl_transferase-like_C_sf
PfamiView protein in Pfam
PF02911 Formyl_trans_C, 1 hit
PF00551 Formyl_trans_N, 1 hit
SUPFAMiSSF50486 SSF50486, 1 hit
SSF53328 SSF53328, 1 hit
TIGRFAMsiTIGR00460 fmt, 1 hit

Sequencei

Sequence statusi: Complete.

Q7U6Z1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILYWGTPA YAVPTLRQLH QAGHTIVGVV SQPDRRRGRG QQLVASAVKQ
60 70 80 90 100
EALNLNLPVF TPERIKKDSD CQAQLAALKA DASVVVAFGQ ILPLEVLEQP
110 120 130 140 150
PLGCWNGHGS LLPRWRGAAP IQWSILDGDA ETGVGVMAME EGLDTGPVLL
160 170 180 190 200
ERRLSIGLQD NAHALAEKLS GLTAELMVEA MPLIEAVGAG PTDERLHRLG
210 220 230 240 250
VQHQAEASCY ARMLCKQDYQ IDWSNSALAI HRQVMGLYPG AQTSWNGKRL
260 270 280 290 300
KLTQTEPLID RLKDQLSPEA QELVGQWPTG GHAGGTVLAC IQDLGLVVSS
310 320 330
SGCPLLIREA QLEGKSRSRG QALVQQMAAA EQQSIGDN
Length:338
Mass (Da):36,499
Last modified:October 1, 2003 - v1
Checksum:iBC6D8C2EF7654886
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX569692 Genomic DNA Translation: CAE07710.1
RefSeqiWP_011128060.1, NC_005070.1

Genome annotation databases

EnsemblBacteriaiCAE07710; CAE07710; SYNW1195
KEGGisyw:SYNW1195

Similar proteinsi

Entry informationi

Entry nameiFMT_SYNPX
AccessioniPrimary (citable) accession number: Q7U6Z1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: October 1, 2003
Last modified: April 25, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health