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Q7U6T0 (G6PI_SYNPX) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:SYNW1256
OrganismSynechococcus sp. (strain WH8102) [Complete proteome] [HAMAP]
Taxonomic identifier84588 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length551 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 551551Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180754

Sites

Active site3491Proton donor By similarity
Active site3781 By similarity
Active site4801 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7U6T0 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 3F5159032675E878

FASTA55160,274
        10         20         30         40         50         60 
MGKPGRSSIP SVGVHHQGPM SFPDFSASDA QIQWQRFCDL LWYHEDLGIW LDISRMHVNP 

        70         80         90        100        110        120 
SHLEQLQPGF DKAFAAMAEL EAGAIANPDE QRQVGHYWLR TPQLAPNEAV RDQIATEIDQ 

       130        140        150        160        170        180 
IDQFGRDVIS GVIKAPGGQP FTDVLWIGIG GSGLGPLLMI RALQGHGSGL PFHFFDNVDP 

       190        200        210        220        230        240 
NGMSAVLAEL DDRLATTLVV TVSKSGGTPE PHLGMEQARH RVESRGGRWA DQAVAITMVD 

       250        260        270        280        290        300 
SKLDREAQQD GWLKSFSMFD WVGGRTSITS AVGLLPGALI GADIRDFLAG AAQMDDATRL 

       310        320        330        340        350        360 
ADLRRNPAAL MAASWFVAGD GKGRRDMVVL PYRDRLEVFS RYLQQLVMES LGKRLDRDGN 

       370        380        390        400        410        420 
EVNQGIAVYG NKGSTDQHAY VQQLRDGVDN FFATFIEVLE DVSDIPVIKD ECPGDFLDGF 

       430        440        450        460        470        480 
LQGTRSALTE GGRQSLSISM RRFDARRLGA LIALFERAVG FYGDLVNINA YHQPGVEAGK 

       490        500        510        520        530        540 
KAAAAILDLQ SRVEAVLKDG APRTVSEIRQ AVGDGSDEAI FWIMRHLAGN DRGYRAEGDW 

       550 
ANPASIRFSC S 

« Hide

References

[1]"The genome of a motile marine Synechococcus."
Palenik B., Brahamsha B., Larimer F.W., Land M.L., Hauser L., Chain P., Lamerdin J.E., Regala W., Allen E.E., McCarren J., Paulsen I.T., Dufresne A., Partensky F., Webb E.A., Waterbury J.
Nature 424:1037-1042(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WH8102.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX569692 Genomic DNA. Translation: CAE07771.1.
RefSeqNP_897349.1. NC_005070.1.

3D structure databases

ProteinModelPortalQ7U6T0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING84588.SYNW1256.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE07771; CAE07771; SYNW1256.
GeneID1731169.
KEGGsyw:SYNW1256.
PATRIC23834032. VBISynSp27240_1317.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000131425.
KOK01810.
OMAFTDVLWI.
OrthoDBEOG64R61J.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_SYNPX
AccessionPrimary (citable) accession number: Q7U6T0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: October 1, 2003
Last modified: June 11, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways