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Q7U6T0

- G6PI_SYNPX

UniProt

Q7U6T0 - G6PI_SYNPX

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Synechococcus sp. (strain WH8102)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (01 Oct 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei349 – 3491Proton donorUniRule annotation
    Active sitei378 – 3781UniRule annotation
    Active sitei480 – 4801UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:SYNW1256
    OrganismiSynechococcus sp. (strain WH8102)
    Taxonomic identifieri84588 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
    ProteomesiUP000001422: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 551551Glucose-6-phosphate isomerasePRO_0000180754Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi84588.SYNW1256.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7U6T0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000131425.
    KOiK01810.
    OMAiFTDVLWI.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7U6T0-1 [UniParc]FASTAAdd to Basket

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    MGKPGRSSIP SVGVHHQGPM SFPDFSASDA QIQWQRFCDL LWYHEDLGIW    50
    LDISRMHVNP SHLEQLQPGF DKAFAAMAEL EAGAIANPDE QRQVGHYWLR 100
    TPQLAPNEAV RDQIATEIDQ IDQFGRDVIS GVIKAPGGQP FTDVLWIGIG 150
    GSGLGPLLMI RALQGHGSGL PFHFFDNVDP NGMSAVLAEL DDRLATTLVV 200
    TVSKSGGTPE PHLGMEQARH RVESRGGRWA DQAVAITMVD SKLDREAQQD 250
    GWLKSFSMFD WVGGRTSITS AVGLLPGALI GADIRDFLAG AAQMDDATRL 300
    ADLRRNPAAL MAASWFVAGD GKGRRDMVVL PYRDRLEVFS RYLQQLVMES 350
    LGKRLDRDGN EVNQGIAVYG NKGSTDQHAY VQQLRDGVDN FFATFIEVLE 400
    DVSDIPVIKD ECPGDFLDGF LQGTRSALTE GGRQSLSISM RRFDARRLGA 450
    LIALFERAVG FYGDLVNINA YHQPGVEAGK KAAAAILDLQ SRVEAVLKDG 500
    APRTVSEIRQ AVGDGSDEAI FWIMRHLAGN DRGYRAEGDW ANPASIRFSC 550
    S 551
    Length:551
    Mass (Da):60,274
    Last modified:October 1, 2003 - v1
    Checksum:i3F5159032675E878
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX569692 Genomic DNA. Translation: CAE07771.1.
    RefSeqiNP_897349.1. NC_005070.1.
    WP_011128120.1. NC_005070.1.

    Genome annotation databases

    EnsemblBacteriaiCAE07771; CAE07771; SYNW1256.
    GeneIDi1731169.
    KEGGisyw:SYNW1256.
    PATRICi23834032. VBISynSp27240_1317.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX569692 Genomic DNA. Translation: CAE07771.1 .
    RefSeqi NP_897349.1. NC_005070.1.
    WP_011128120.1. NC_005070.1.

    3D structure databases

    ProteinModelPortali Q7U6T0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 84588.SYNW1256.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAE07771 ; CAE07771 ; SYNW1256 .
    GeneIDi 1731169.
    KEGGi syw:SYNW1256.
    PATRICi 23834032. VBISynSp27240_1317.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000131425.
    KOi K01810.
    OMAi FTDVLWI.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: WH8102.

    Entry informationi

    Entry nameiG6PI_SYNPX
    AccessioniPrimary (citable) accession number: Q7U6T0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2005
    Last sequence update: October 1, 2003
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3