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Q7U646

- GLGB_SYNPX

UniProt

Q7U646 - GLGB_SYNPX

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Protein

1,4-alpha-glucan branching enzyme GlgB

Gene

glgB

Organism
Synechococcus sp. (strain WH8102)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei431 – 4311NucleophileUniRule annotation
Active sitei484 – 4841Proton donorUniRule annotation

GO - Molecular functioni

  1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-HAMAP
  2. cation binding Source: InterPro
  3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

UniPathwayiUPA00164.

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgBUniRule annotation (EC:2.4.1.18UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferaseUniRule annotation
Alpha-(1->4)-glucan branching enzymeUniRule annotation
Glycogen branching enzymeUniRule annotation
Short name:
BEUniRule annotation
Gene namesi
Name:glgBUniRule annotation
Ordered Locus Names:SYNW1494
OrganismiSynechococcus sp. (strain WH8102)
Taxonomic identifieri84588 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
ProteomesiUP000001422: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7757751,4-alpha-glucan branching enzyme GlgBPRO_0000188757Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi84588.SYNW1494.

Structurei

3D structure databases

ProteinModelPortaliQ7U646.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0296.
HOGENOMiHOG000283037.
KOiK00700.
OMAiRSISKRI.
OrthoDBiEOG6JX7GT.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_00685. GlgB.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsiTIGR01515. branching_enzym. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7U646-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGGAAVLDWM VQDGERLANC RHDHPLAILG PQPSDAGWTV RVWMPEAHSV
60 70 80 90 100
TLLEGGREAL MTAPNHPWVF ETTLSHDPGS NYKVRVERGG ITHEQHDPWA
110 120 130 140 150
FRDEWMGDMD RHLFAQGNHH HIWQRMGAHL TQRDGISGVM FCLWAPHALS
160 170 180 190 200
VSILGDLNSW DGRHHPMQQR LGGIWELFIP GLAEGSLYKY EIRTQDGHCY
210 220 230 240 250
QKADPYGFQH EVRPDNSSVV ARLDGFQWSD GSWMQRRDSS NPLEQPISVY
260 270 280 290 300
EMHLGSWIHA SAEEPWIQPD GSPRAPVPAA DMKPGARLLT YAELAARLIP
310 320 330 340 350
YVKERGFTHI ELMPITEHPF DGSWGYQVTG WYAPTSRYGT PDEFRAFVDR
360 370 380 390 400
CHAEGIGVII DWVPGHFPKD AHGLAFFDGT HLYEHGDPRI GEHKEWGTLI
410 420 430 440 450
FNYSRNEVRN FLVANLVFWF EQFHIDGIRV DAVASMLYRD YLRPDGEWLA
460 470 480 490 500
NEHGGRENTE AVQFLQQANH VLFQHFPGAL SIAEESTTWP MVTQPTEIGG
510 520 530 540 550
LGFNLKWNMG WMHDMLDYFE LDPWFRQFHQ NNITFSIWYT YTENFMLALS
560 570 580 590 600
HDEVVHGKSH LLHKMPGDDW QKYANTRALL AYMWTHPGKK TIFMGMEFGQ
610 620 630 640 650
RAEWNVWGDL QWDLLNYEPH KGIQLLVDDL NTLYKAEPAL WRDDFDQFGF
660 670 680 690 700
QWIDCNDNRH SVISFMRRES SSGTWLVVVA NFTPQSHSHY RVGVPLAGFY
710 720 730 740 750
EEIFNTDAAR YGGSNLGNMG GKPTDEWSIH GYENSLDLCL PPLSLLVFRH
760 770
DPKRSLQAAS ASACDKADDE TADTN
Length:775
Mass (Da):88,837
Last modified:October 1, 2003 - v1
Checksum:iBDA0C16BA4C9D509
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX569693 Genomic DNA. Translation: CAE08009.1.
RefSeqiNP_897587.1. NC_005070.1.
WP_011128358.1. NC_005070.1.

Genome annotation databases

EnsemblBacteriaiCAE08009; CAE08009; SYNW1494.
GeneIDi1730383.
KEGGisyw:SYNW1494.
PATRICi23834612. VBISynSp27240_1606.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX569693 Genomic DNA. Translation: CAE08009.1 .
RefSeqi NP_897587.1. NC_005070.1.
WP_011128358.1. NC_005070.1.

3D structure databases

ProteinModelPortali Q7U646.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 84588.SYNW1494.

Protein family/group databases

CAZyi CBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE08009 ; CAE08009 ; SYNW1494 .
GeneIDi 1730383.
KEGGi syw:SYNW1494.
PATRICi 23834612. VBISynSp27240_1606.

Phylogenomic databases

eggNOGi COG0296.
HOGENOMi HOG000283037.
KOi K00700.
OMAi RSISKRI.
OrthoDBi EOG6JX7GT.

Enzyme and pathway databases

UniPathwayi UPA00164 .

Family and domain databases

Gene3Di 2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPi MF_00685. GlgB.
InterProi IPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view ]
PANTHERi PTHR10357. PTHR10357. 1 hit.
Pfami PF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view ]
PIRSFi PIRSF000463. GlgB. 1 hit.
SUPFAMi SSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsi TIGR01515. branching_enzym. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WH8102.

Entry informationi

Entry nameiGLGB_SYNPX
AccessioniPrimary (citable) accession number: Q7U646
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: October 1, 2003
Last modified: October 1, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3