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Q7U646 (GLGB_SYNPX) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:SYNW1494
OrganismSynechococcus sp. (strain WH8102) [Complete proteome] [HAMAP]
Taxonomic identifier84588 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length775 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7757751,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_0000188757

Sites

Active site4311Nucleophile By similarity
Active site4841Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7U646 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: BDA0C16BA4C9D509

FASTA77588,837
        10         20         30         40         50         60 
MGGAAVLDWM VQDGERLANC RHDHPLAILG PQPSDAGWTV RVWMPEAHSV TLLEGGREAL 

        70         80         90        100        110        120 
MTAPNHPWVF ETTLSHDPGS NYKVRVERGG ITHEQHDPWA FRDEWMGDMD RHLFAQGNHH 

       130        140        150        160        170        180 
HIWQRMGAHL TQRDGISGVM FCLWAPHALS VSILGDLNSW DGRHHPMQQR LGGIWELFIP 

       190        200        210        220        230        240 
GLAEGSLYKY EIRTQDGHCY QKADPYGFQH EVRPDNSSVV ARLDGFQWSD GSWMQRRDSS 

       250        260        270        280        290        300 
NPLEQPISVY EMHLGSWIHA SAEEPWIQPD GSPRAPVPAA DMKPGARLLT YAELAARLIP 

       310        320        330        340        350        360 
YVKERGFTHI ELMPITEHPF DGSWGYQVTG WYAPTSRYGT PDEFRAFVDR CHAEGIGVII 

       370        380        390        400        410        420 
DWVPGHFPKD AHGLAFFDGT HLYEHGDPRI GEHKEWGTLI FNYSRNEVRN FLVANLVFWF 

       430        440        450        460        470        480 
EQFHIDGIRV DAVASMLYRD YLRPDGEWLA NEHGGRENTE AVQFLQQANH VLFQHFPGAL 

       490        500        510        520        530        540 
SIAEESTTWP MVTQPTEIGG LGFNLKWNMG WMHDMLDYFE LDPWFRQFHQ NNITFSIWYT 

       550        560        570        580        590        600 
YTENFMLALS HDEVVHGKSH LLHKMPGDDW QKYANTRALL AYMWTHPGKK TIFMGMEFGQ 

       610        620        630        640        650        660 
RAEWNVWGDL QWDLLNYEPH KGIQLLVDDL NTLYKAEPAL WRDDFDQFGF QWIDCNDNRH 

       670        680        690        700        710        720 
SVISFMRRES SSGTWLVVVA NFTPQSHSHY RVGVPLAGFY EEIFNTDAAR YGGSNLGNMG 

       730        740        750        760        770 
GKPTDEWSIH GYENSLDLCL PPLSLLVFRH DPKRSLQAAS ASACDKADDE TADTN 

« Hide

References

[1]"The genome of a motile marine Synechococcus."
Palenik B., Brahamsha B., Larimer F.W., Land M.L., Hauser L., Chain P., Lamerdin J.E., Regala W., Allen E.E., McCarren J., Paulsen I.T., Dufresne A., Partensky F., Webb E.A., Waterbury J.
Nature 424:1037-1042(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WH8102.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX569693 Genomic DNA. Translation: CAE08009.1.
RefSeqNP_897587.1. NC_005070.1.

3D structure databases

ProteinModelPortalQ7U646.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING84588.SYNW1494.

Protein family/group databases

CAZyCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE08009; CAE08009; SYNW1494.
GeneID1730383.
KEGGsyw:SYNW1494.
PATRIC23834612. VBISynSp27240_1606.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMARSISKRI.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_SYNPX
AccessionPrimary (citable) accession number: Q7U646
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: October 1, 2003
Last modified: June 11, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries