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Q7U5L7 (MQO_SYNPX) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:SYNW1686
OrganismSynechococcus sp. (strain WH8102) [Complete proteome] [HAMAP]
Taxonomic identifier84588 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length502 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 502502Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_0000128757

Sequences

Sequence LengthMass (Da)Tools
Q7U5L7 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 2DCD6702206618B1

FASTA50254,428
        10         20         30         40         50         60 
MQQDGSFSAD ARFDAVLVGA GIMSATLAAL LHELDPGLRL LLVERLEGPA RESSAANNNA 

        70         80         90        100        110        120 
GTGHAANCEL NYTPMQADGT VATAKAVAIN AGFERSLEFW GSLRERGELD TSSFLHQAAH 

       130        140        150        160        170        180 
ISAVWTAENI AFLRQRFEQL SEIPAFAAMR WSEERTELTD WMPLVMAGRD LKQPVAATRI 

       190        200        210        220        230        240 
ERGTDVDFGA LTRAYLEPLQ RSGALCVEYG TQVRDIKRLR RGDMTEADWR VILQGPSGKR 

       250        260        270        280        290        300 
EVRAPFVFLG AGGGALPLLQ RSGIPEADDF AGFPVSGLWL VCGDAQLAAK QRAKVYGKAA 

       310        320        330        340        350        360 
VGAPPMSVPH LDTRWIDGQR SLLFGPFAGF SSKFLKQGSL FDLPSSVRPT NLLPMLQVGA 

       370        380        390        400        410        420 
TNIELVQYLI NQLRQSPEER HDALQQFMPT ARAEDWSLSV AGQRVQIIKR SKQGGRLQLG 

       430        440        450        460        470        480 
TEVVASMDGS LAALLGASPG ASTAVTIMLE VLQRCFKQRL ASAAWNERLQ ALLPSIGGDP 

       490        500 
VQDPALLLAM RQRSDALLDL QG

« Hide

References

[1]"The genome of a motile marine Synechococcus."
Palenik B., Brahamsha B., Larimer F.W., Land M.L., Hauser L., Chain P., Lamerdin J.E., Regala W., Allen E.E., McCarren J., Paulsen I.T., Dufresne A., Partensky F., Webb E.A., Waterbury J.
Nature 424:1037-1042(2003) [PubMed: 12917641] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WH8102.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX569693 Genomic DNA. Translation: CAE08201.1.
RefSeqNP_897777.1. NC_005070.1.

3D structure databases

ProteinModelPortalQ7U5L7.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ7U5L7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1731458.
GenomeReviewsGene locus SYNW1686 in contig BX548020_GR.
KEGGsyw:SYNW1686.
PATRIC23835043. VBISynSp27240_1816.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0579.
HOGENOMHBG289663.
OMANTQFEVS.
PhylomeDBQ7U5L7.
ProtClustDBPRK05257.

Enzyme and pathway databases

BioCycSSP84588:SYNW1686OR3030-MONOMER.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_SYNPX
AccessionPrimary (citable) accession number: Q7U5L7
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: October 1, 2003
Last modified: January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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