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Q7U524

- RNPA_SYNPX

UniProt

Q7U524 - RNPA_SYNPX

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Protein

Ribonuclease P protein component

Gene
rnpA, SYNW1888
Organism
Synechococcus sp. (strain WH8102)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
  2. tRNA binding Source: InterPro

GO - Biological processi

  1. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component (EC:3.1.26.5)
Short name:
RNase P protein
Short name:
RNaseP protein
Alternative name(s):
Protein C5
Gene namesi
Name:rnpA
Ordered Locus Names:SYNW1888
OrganismiSynechococcus sp. (strain WH8102)
Taxonomic identifieri84588 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
ProteomesiUP000001422: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 128128Ribonuclease P protein componentUniRule annotationPRO_0000198550Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit By similarity.

Protein-protein interaction databases

STRINGi84588.SYNW1888.

Structurei

3D structure databases

ProteinModelPortaliQ7U524.

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.

Phylogenomic databases

eggNOGiNOG47167.
HOGENOMiHOG000266301.
KOiK03536.
OMAiMRLKGHR.
OrthoDBiEOG6N94CP.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P.
InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
[Graphical view]
PfamiPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7U524-1 [UniParc]FASTAAdd to Basket

« Hide

MALPASMRLR GHRCFNRLHR IGRRHHGDWM VLRVMPEEPR LLRPELRRHP    50
TRCCRCALVI SSKVSKRAVR RNRLRRLLHQ HLRQQLEHRG DLAGRWVLIS 100
LRPEASEAEP SQLLEECDSL LSSAGLGQ 128
Length:128
Mass (Da):14,987
Last modified:October 1, 2003 - v1
Checksum:i57948B9992B07314
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX569694 Genomic DNA. Translation: CAE08403.1.
RefSeqiNP_897979.1. NC_005070.1.
WP_011128746.1. NC_005070.1.

Genome annotation databases

EnsemblBacteriaiCAE08403; CAE08403; SYNW1888.
GeneIDi1731446.
KEGGisyw:SYNW1888.
PATRICi23835461. VBISynSp27240_2022.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX569694 Genomic DNA. Translation: CAE08403.1 .
RefSeqi NP_897979.1. NC_005070.1.
WP_011128746.1. NC_005070.1.

3D structure databases

ProteinModelPortali Q7U524.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 84588.SYNW1888.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE08403 ; CAE08403 ; SYNW1888 .
GeneIDi 1731446.
KEGGi syw:SYNW1888.
PATRICi 23835461. VBISynSp27240_2022.

Phylogenomic databases

eggNOGi NOG47167.
HOGENOMi HOG000266301.
KOi K03536.
OMAi MRLKGHR.
OrthoDBi EOG6N94CP.

Family and domain databases

Gene3Di 3.30.230.10. 1 hit.
HAMAPi MF_00227. RNase_P.
InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
[Graphical view ]
Pfami PF00825. Ribonuclease_P. 1 hit.
[Graphical view ]
SUPFAMi SSF54211. SSF54211. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WH8102.

Entry informationi

Entry nameiRNPA_SYNPX
AccessioniPrimary (citable) accession number: Q7U524
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: October 1, 2003
Last modified: September 3, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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