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Q7U3S0 (SPEA_SYNPX) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Biosynthetic arginine decarboxylase

Short name=ADC
EC=4.1.1.19
Gene names
Name:speA
Ordered Locus Names:SYNW2359
OrganismSynechococcus sp. (strain WH8102) [Complete proteome] [HAMAP]
Taxonomic identifier84588 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length644 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the biosynthesis of agmatine from arginine By similarity. HAMAP-Rule MF_01417

Catalytic activity

L-arginine = agmatine + CO2. HAMAP-Rule MF_01417

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01417

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01417

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 644644Biosynthetic arginine decarboxylase HAMAP-Rule MF_01417
PRO_0000149980

Regions

Region287 – 29711Substrate-binding Potential

Amino acid modifications

Modified residue1051N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7U3S0 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: FAAF6AE897BA61EC

FASTA64470,760
        10         20         30         40         50         60 
MQVADSEGWS IQDSAALYGL DRWGEPYFTI NGRGHISVQP QGERGGSLDL VELVSELRGR 

        70         80         90        100        110        120 
NLGLPLLIRF DDILEDRLER LHAAFERAIA QYSYTGRYQG VFPVKCNQQR HVVEELVICG 

       130        140        150        160        170        180 
KRWNFGLEAG SKAELLIALS LLDDPEALLI CNGYKDRLYI ETAILARRLG RQPVVVIEQP 

       190        200        210        220        230        240 
DEVDRIIEAS KSLGAAPYIG VRAKLSSRST GRWGSSVGDK AKFGLSIPEL LATVERLRES 

       250        260        270        280        290        300 
NLLPDLRLLH FHIGSQINDI AVLKDALQEA GQIYVELTRL GAPMGFLDVG GGLGIDYDGS 

       310        320        330        340        350        360 
RTASAASTNY SLQNYANDVV ATVRECCEPN AVAVPTLVSE SGRAIASHFS LLVFDVLGSS 

       370        380        390        400        410        420 
ALSASIPNAS GDEPLTVRNL RDTLVTIQEL SGTADAQLVR LQEAWNDALK FKQDALAAFR 

       430        440        450        460        470        480 
LGYMGLPDRA SAEQLTWACA DAIAQRLPKE QAIPEELAAL SKALAGTYYA NLSIFRSAPD 

       490        500        510        520        530        540 
TWAIDQLFPV VPIQKLNQRP TRLANLADLT CDSDGRLDRF IGDGQPKQLL ELHELDDNNP 

       550        560        570        580        590        600 
YLIGLFLSGA YQEVMGNLHN LFGTTNAVHI RLSPGGSYRI DHVVRGDTNA DVLEAMEHDP 

       610        620        630        640 
RVLLERLRVA AEAAINDGQL RIDESRRLLD HLESSLRQTT YLQD 

« Hide

References

[1]"The genome of a motile marine Synechococcus."
Palenik B., Brahamsha B., Larimer F.W., Land M.L., Hauser L., Chain P., Lamerdin J.E., Regala W., Allen E.E., McCarren J., Paulsen I.T., Dufresne A., Partensky F., Webb E.A., Waterbury J.
Nature 424:1037-1042(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WH8102.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX569695 Genomic DNA. Translation: CAE08874.1.
RefSeqNP_898448.1. NC_005070.1.

3D structure databases

ProteinModelPortalQ7U3S0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING84588.SYNW2359.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE08874; CAE08874; SYNW2359.
GeneID1730904.
KEGGsyw:SYNW2359.
PATRIC23836480. VBISynSp27240_2510.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1166.
HOGENOMHOG000029191.
KOK01585.
OMAMIHFHIG.
OrthoDBEOG676Z0R.
ProtClustDBPRK05354.

Family and domain databases

Gene3D2.40.37.10. 2 hits.
HAMAPMF_01417. SpeA.
InterProIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
[Graphical view]
PfamPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR01273. speA. 1 hit.
PROSITEPS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPEA_SYNPX
AccessionPrimary (citable) accession number: Q7U3S0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: October 1, 2003
Last modified: February 19, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families