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Q7U374 (TRMD_BORPA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
tRNA (guanine-N(1)-)-methyltransferase
EC=2.1.1.228
Alternative name(s):
M1G-methyltransferase
tRNA [GM37] methyltransferase
Gene names
Name:trmD
Ordered Locus Names:BPP2865
OrganismBordetella parapertussis [Complete proteome] [HAMAP]
Taxonomic identifier519 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length257 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates guanosine-37 in various tRNAs By similarity. HAMAP MF_00605

Catalytic activity

S-adenosyl-L-methionine + guanine(37) in tRNA = S-adenosyl-L-homocysteine + N(1)-methylguanine(37) in tRNA. HAMAP MF_00605

Subunit structure

Homodimer By similarity. HAMAP MF_00605

Subcellular location

Cytoplasm Potential HAMAP MF_00605.

Sequence similarities

Belongs to the RNA methyltransferase TrmD family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionRNA binding

Inferred from electronic annotation. Source: InterPro

tRNA (guanine-N1-)-methyltransferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 257257tRNA (guanine-N(1)-)-methyltransferase HAMAP MF_00605
PRO_0000060337

Regions

Region137 – 1426S-adenosyl-L-methionine binding By similarity

Sites

Binding site1171S-adenosyl-L-methionine; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7U374 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: AFDCC1E027883C61

FASTA25727,751
        10         20         30         40         50         60 
MRFDVVTLFP DMFGLVRDQG VTGRAHAQGL WALHAWNPRD FTQDVHRTVD DRPYGGGPGM 

        70         80         90        100        110        120 
VMMAAPLEAA VAAAQAARAA QGLQAAPVIL LSPAGRRYDQ AEATTLAAGT GAIFICGRYE 

       130        140        150        160        170        180 
GVDQRFIERC VTHELSLGDF VLSGGELAAL AMMDAAVRLL PGVLNDGDSA LQDSFNAALD 

       190        200        210        220        230        240 
GLLDSPHYTR PEVYEGVPVP QPLLSGHHAN IARWRREQSL RLTASRRPEL IERARGEGRL 

       250 
SKADERFLAG LAGERKS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX640431 Genomic DNA. Translation: CAE38157.1.
RefSeqNP_885064.1. NC_002928.3.

3D structure databases

ProteinModelPortalQ7U374.
SMRQ7U374. Positions 1-255.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1666034.
GenomeReviewsGene locus BPP2865 in contig BX470249_GR.
KEGGbpa:BPP2865.
PATRIC21149664. VBIBorPar43418_3009.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG285805.
OMAVCGRFEG.
PhylomeDBQ7U374.
ProtClustDBPRK00026.

Enzyme and pathway databases

BioCycBPAR257311:BPP2865-MONOMER.

Family and domain databases

HAMAPMF_00605. TrmD.
[Tree]
InterProIPR016009. tRNA_m1G_MeTrfase.
IPR002649. tRNA_m1G_MeTrfase_bac.
IPR023148. tRNA_m1G_MeTrfase_C.
[Graphical view]
Gene3DG3DSA:1.10.1270.20. tRNA_m1G_MeTrfase_C. 1 hit.
KOK00554.
PANTHERPTHR10056. PTHR10056. 1 hit.
PfamPF01746. tRNA_m1G_MT. 1 hit.
[Graphical view]
PIRSFPIRSF000386. tRNA_mtase. 1 hit.
TIGRFAMsTIGR00088. TrmD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRMD_BORPA
AccessionPrimary (citable) accession number: Q7U374
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: October 1, 2003
Last modified: January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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