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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi30 – 37ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair, DNA replication, SOS response

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecFUniRule annotation
Gene namesi
Name:recFUniRule annotation
Ordered Locus Names:Mb0003
OrganismiMycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Taxonomic identifieri233413 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001419 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001964311 – 385DNA replication and repair protein RecFAdd BLAST385

Structurei

3D structure databases

ProteinModelPortaliQ7U314.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000269561.
KOiK03629.
OMAiKVQTFIT.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF. 1 hit.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7U314-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYVRHLGLRD FRSWACVDLE LHPGRTVFVG PNGYGKTNLI EALWYSTTLG
60 70 80 90 100
SHRVSADLPL IRVGTDRAVI STIVVNDGRE CAVDLEIATG RVNKARLNRS
110 120 130 140 150
SVRSTRDVVG VLRAVLFAPE DLGLVRGDPA DRRRYLDDLA IVRRPAIAAV
160 170 180 190 200
RAEYERVVRQ RTALLKSVPG ARYRGDRGVF DTLEVWDSRL AEHGAELVAA
210 220 230 240 250
RIDLVNQLAP EVKKAYQLLA PESRSASIGY RASMDVTGPS EQSDTDRQLL
260 270 280 290 300
AARLLAALAA RRDAELERGV CLVGPHRDDL ILRLGDQPAK GFASHGEAWS
310 320 330 340 350
LAVALRLAAY QLLRVDGGEP VLLLDDVFAE LDVMRRRALA TAAESAEQVL
360 370 380
VTAAVLEDIP AGWDARRVHI DVRADDTGSM SVVLP
Length:385
Mass (Da):42,186
Last modified:October 1, 2003 - v1
Checksum:i341551DD18A51693
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248333 Genomic DNA. Translation: CDO41236.1.
RefSeqiNP_853673.1. NC_002945.3.
WP_003400273.1. NC_002945.3.

Genome annotation databases

EnsemblBacteriaiCDO41236; CDO41236; Mb0003.
GeneIDi1090745.
KEGGimbo:Mb0003.
PATRICi18001663. VBIMycBov88188_0003.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248333 Genomic DNA. Translation: CDO41236.1.
RefSeqiNP_853673.1. NC_002945.3.
WP_003400273.1. NC_002945.3.

3D structure databases

ProteinModelPortaliQ7U314.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCDO41236; CDO41236; Mb0003.
GeneIDi1090745.
KEGGimbo:Mb0003.
PATRICi18001663. VBIMycBov88188_0003.

Phylogenomic databases

HOGENOMiHOG000269561.
KOiK03629.
OMAiKVQTFIT.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF. 1 hit.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRECF_MYCBO
AccessioniPrimary (citable) accession number: Q7U314
Secondary accession number(s): X2BDR1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: October 1, 2003
Last modified: September 7, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.