Q7U000 (Q7U000_MYCBO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
PROBABLE ACONITATE HYDRATASE ACN (Citrate hydro-lyase) (Aconitase) EMBL CAD96178.1
EC=4.2.1.3 EMBL CAD96178.1

Gene names

Name:	acn EMBL CAD96178.1
Ordered Locus Names:	Mb1511c

Organism

Mycobacterium bovis [Complete proteome] [HAMAP]

Taxonomic identifier

1765 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	943 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL CAD96178.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	aconitate hydratase activity Inferred from electronic annotation. Source: EC citrate hydro-lyase (cis-aconitate-forming) activity Inferred from electronic annotation. Source: EC isocitrate hydro-lyase (cis-aconitate-forming) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7U000 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 2403292221124D1E	FASTA	943	102,449
	10 20 30 40 50 60 MTSKSVNSFG AHDTLKVGEK SYQIYRLDAV PNTAKLPYSL KVLAENLLRN EDGSNITKDH 70 80 90 100 110 120 IEAIANWDPK AEPSIEIQYT PARVVMQDFT GVPCIVDLAT MREAIADLGG NPDKVNPLAP 130 140 150 160 170 180 ADLVIDHSVI ADLFGRADAF ERNVEIEYQR NGERYQFLRW GQGAFDDFKV VPPGTGIVHQ 190 200 210 220 230 240 VNIEYLASVV MTRDGVAYPD TCVGTDSHTT MVNGLGVLGW GVGGIEAEAA MLGQPVSMLI 250 260 270 280 290 300 PRVVGFRLTG EIQPGVTATD VVLTVTEMLR QHGVVGKFVE FYGEGVAEVP LANRATLGNM 310 320 330 340 350 360 SPEFGSTAAI FPIDEETIKY LRFTGRTPEQ VALVEAYAKA QGMWHDPKHE PEFSEYLELN 370 380 390 400 410 420 LSDVVPSIAG PKRPQDRIAL AQAKSTFREQ IYHYVGNGSP DSPHDPHSKL DEVVEETFPA 430 440 450 460 470 480 SDPGQLTFAN DDVATDETVH SAAAHADGRV SNPVRVKSDE LGEFVLDHGA VVIAAITSCT 490 500 510 520 530 540 NTSNPEVMLG AALLARNAVE KGLTSKPWVK TTIAPGSQVV NDYYDRSGLW PYLEKLGFYL 550 560 570 580 590 600 VGYGCTTCIG NSGPLPEEIS KAVNDNDLSV TAVLSGNRNF EGRINPDVKM NYLASPPLVI 610 620 630 640 650 660 AYALAGTMDF DFQTQPLGQD KDGKNVFLRD IWPSQQDVSD TIAAAINQEM FTRNYADVFK 670 680 690 700 710 720 GDDRWRNLPT PSGNTFEWDP NSTYVRKPPY FEGMTAKPEP VGNISGARVL ALLGDSVTTD 730 740 750 760 770 780 HISPAGAIKP GTPAARYLDE HGVDRKDYNS FGSRRGNHEV MIRGTFANIR LRNQLLDDVS 790 800 810 820 830 840 GGYTRDFTQP GGPQAFIYDA AQNYAAQHIP LVVFGGKEYG SGSSRDWAAK GTLLLGVRAV 850 860 870 880 890 900 IAESFERIHR SNLIGMGVIP LQFPEGKSAS SLGLDGTEVF DITGIDVLND GKTPKTVCVQ 910 920 930 940 ATKGDGATIE FDAVVRIDTP GEADYYRNGG ILQYVLRNIL KSG

References

[1]

"The complete genome sequence of Mycobacterium bovis." Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M., Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B., Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J. , Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G. Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003) [PubMed: 12788972] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-935 / AF2122/97.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX248339 Genomic DNA. Translation: CAD96178.1.
RefSeq	NP_855163.1. NC_002945.3.
3D structure databases
HSSP	HSSP built from PDB template 1AMJ based on UniProtKB P20004.
ProteinModelPortal	Q7U000.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000014907; EBMYCP00000014742; EBMYCG00000014904.
GeneID	1092368.
GenomeReviews	Gene locus Mb1511c in contig BX248333_GR.
KEGG	mbo:Mb1511c.
PATRIC	18005010. VBIMycBov88188_1652.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000014567.
HOGENOM	HBG289738.
OMA	YSKAQGM.
ProtClustDB	PRK09277.
Family and domain databases
InterPro	IPR015931. Acnase/IPM_dHydase_lsu_aba_1/3. IPR015937. Acoase/IPM_deHydtase. IPR001030. Acoase/IPM_deHydtase_lsu_aba. IPR015928. Aconitase/3IPM_dehydase_swvl. IPR015934. Aconitase/Fe_reg_prot_2/AcnD. IPR015932. Aconitase/IPMdHydase_lsu_aba_2. IPR018136. Aconitase_4Fe-4S_BS. IPR000573. AconitaseA/IPMdHydase_ssu_swvl. [Graphical view]
Gene3D	G3DSA:3.30.499.10. Acnase/IPM_dHydase_lsu_aba_1/3. 3 hits. G3DSA:3.20.19.10. Aconitase/3IPM_dehydase_swvl. 1 hit. G3DSA:3.40.1060.10. Aconitase/IPMdHydase_lsu_aba_2. 1 hit.
KO	K01681.
PANTHER	PTHR11670. Aconitase-like_core. 1 hit. PTHR11670:SF1. Aconitase/Fe_reg_prot_2/AcnD. 1 hit.
Pfam	PF00330. Aconitase. 2 hits. PF00694. Aconitase_C. 1 hit. [Graphical view]
PRINTS	PR00415. ACONITASE.
SUPFAM	SSF52016. Aconitase/3IPM_dehydase_swvl. 1 hit. SSF53732. Aconitase_N. 1 hit.
PROSITE	PS00450. ACONITASE_1. 1 hit. PS01244. ACONITASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7U000_MYCBO

Accession

Primary (citable) accession number: Q7U000

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	December 14, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)