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Q7TZN1 (PKNF_MYCBO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase PknF

EC=2.7.11.1
Gene names
Name:pknF
Ordered Locus Names:Mb1775
OrganismMycobacterium bovis (strain ATCC BAA-935 / AF2122/97) [Complete proteome] [HAMAP]
Taxonomic identifier233413 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex

Protein attributes

Sequence length476 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Post-translational modification

Dephosphorylated by PstP By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 476476Serine/threonine-protein kinase PknF
PRO_0000171212

Regions

Domain12 – 279268Protein kinase
Nucleotide binding18 – 269ATP By similarity

Sites

Active site1371Proton acceptor By similarity
Binding site411ATP By similarity

Amino acid modifications

Modified residue81Phosphothreonine; by autocatalysis By similarity
Modified residue131Phosphothreonine; by autocatalysis By similarity
Modified residue1731Phosphothreonine; by autocatalysis By similarity
Modified residue1751Phosphothreonine; by autocatalysis By similarity
Modified residue2871Phosphothreonine; by autocatalysis By similarity
Modified residue2901Phosphoserine; by autocatalysis By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7TZN1 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: FD16541A9139163C

FASTA47650,698
        10         20         30         40         50         60 
MPLAEGSTFA GFTIVRQLGS GGMGEVYLAR HPRLPRQDAL KVLRADVSAD GEYRARFNRE 

        70         80         90        100        110        120 
ADAAASLWHP HIVAVHDRGE FDGQLWIDMD FVDGTDTVSL LRDRYPNGMP GPEVTEIITA 

       130        140        150        160        170        180 
VAEALDYAHE RRLLHRDVKP ANILIANPDS PDRRIMLADF GIAGWVDDPS GLTATNMTVG 

       190        200        210        220        230        240 
TVSYAAPEQL MGNELDGRAD QYALAATAFH LLTGSPPFQH ANPAVVISQH LSASPPAIGD 

       250        260        270        280        290        300 
RVPELTPLDP VFAKALAKQP KDRYQRCVDF ARALGHRLGG AGDPDDTRVS QPVAVAAPAK 

       310        320        330        340        350        360 
RSLLRTAVIV PAVLAMLLVM AVAVTVREFQ RADDERAAQP ARTRTTTSAG TTTSVAPAST 

       370        380        390        400        410        420 
TRPAPTTPTT TGAADTATAS PTAAVVAIGA LCFPLGSTGT TKTGATAYCS TLQGTNTTIW 

       430        440        450        460        470 
SLTEDTVASP TVTATADPTE APLPIEQESP IRVCMQQTGQ TRRECREEIR RSNGWP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX248333 Genomic DNA. Translation: CDO43023.1.
RefSeqNP_855427.1. NC_002945.3.

3D structure databases

ProteinModelPortalQ7TZN1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING233413.Mb1775.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD94477; CAD94477; Mb1775.
GeneID1092808.
KEGGmbo:Mb1775.
PATRIC18005588. VBIMycBov88188_1939.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000077804.
KOK08884.
OMAPEIVEGH.
OrthoDBEOG6B35XT.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKNF_MYCBO
AccessionPrimary (citable) accession number: Q7TZN1
Secondary accession number(s): X2BJ00
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: October 1, 2003
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families