SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q7TYY6

- PKNL_MYCBO

UniProt

Q7TYY6 - PKNL_MYCBO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Serine/threonine-protein kinase PknL
Gene
pknL, Mb2198
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei48 – 481ATP By similarity
Active sitei142 – 1421Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi25 – 339ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase PknL (EC:2.7.11.1)
Gene namesi
Name:pknL
Ordered Locus Names:Mb2198
OrganismiMycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Taxonomic identifieri233413 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001419: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 368368Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei369 – 38921Helical; Reviewed prediction
Add
BLAST
Topological domaini390 – 39910Extracellular Reviewed prediction

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 399399Serine/threonine-protein kinase PknL
PRO_0000171225Add
BLAST

Post-translational modificationi

Autophosphorylated By similarity.

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi233413.Mb2198.

Structurei

3D structure databases

ProteinModelPortaliQ7TYY6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 278260Protein kinase
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037187.
KOiK08884.
OMAiIVENIGS.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TYY6-1 [UniParc]FASTAAdd to Basket

« Hide

MVEAGTRDPL ESALLDSRYL VQAKIASGGT STVYRGLDVR LDRPVALKVM    50
DARYAGDEQF LTRFRLEARA VARLNNRALV AVYDQGKDGR HPFLVMELIE 100
GGTLRELLIE RGPMPPHAVV AVLRPVLGGL AAAHRAGLVH RDVKPENILI 150
SDDGDVKLAD FGLVRAVAAA SITSTGVILG TAAYLSPEQV RDGNADPRSD 200
VYSVGVLVYE LLTGHTPFTG DSALSIAYQR LDADVPRASA VIDGVPPQFD 250
ELVACATARN PADRYADAIA MGADLEAIAE ELALPEFRVP APRNSAQHRS 300
AALYRSRITQ QGQLGAKPVH HPTRQLTRQP GDCSEPASGS EPEHEPITGQ 350
FAGIAIEEFI WARQHARRMV LVWVSVVLAI TGLVASAAWT IGSNLSGLL 399
Length:399
Mass (Da):42,818
Last modified:October 1, 2003 - v1
Checksum:iE896CEA19FB5A16A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX248333 Genomic DNA. Translation: CDO43452.1.
RefSeqiNP_855847.1. NC_002945.3.

Genome annotation databases

EnsemblBacteriaiCAD97051; CAD97051; Mb2198.
GeneIDi1091294.
KEGGimbo:Mb2198.
PATRICi18006536. VBIMycBov88188_2414.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX248333 Genomic DNA. Translation: CDO43452.1 .
RefSeqi NP_855847.1. NC_002945.3.

3D structure databases

ProteinModelPortali Q7TYY6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 233413.Mb2198.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD97051 ; CAD97051 ; Mb2198 .
GeneIDi 1091294.
KEGGi mbo:Mb2198.
PATRICi 18006536. VBIMycBov88188_2414.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037187.
KOi K08884.
OMAi IVENIGS.
OrthoDBi EOG6B35XT.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-935 / AF2122/97.

Entry informationi

Entry nameiPKNL_MYCBO
AccessioniPrimary (citable) accession number: Q7TYY6
Secondary accession number(s): X2BJJ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: October 1, 2003
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi