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Q7TYY6 (PKNL_MYCBO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase PknL

EC=2.7.11.1
Gene names
Name:pknL
Ordered Locus Names:Mb2198
OrganismMycobacterium bovis (strain ATCC BAA-935 / AF2122/97) [Complete proteome] [HAMAP]
Taxonomic identifier233413 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subcellular location

Cell membrane; Single-pass membrane protein Potential.

Post-translational modification

Autophosphorylated By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Serine/threonine-protein kinase PknL
PRO_0000171225

Regions

Topological domain1 – 368368Cytoplasmic Potential
Transmembrane369 – 38921Helical; Potential
Topological domain390 – 39910Extracellular Potential
Domain19 – 278260Protein kinase
Nucleotide binding25 – 339ATP By similarity

Sites

Active site1421Proton acceptor By similarity
Binding site481ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7TYY6 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: E896CEA19FB5A16A

FASTA39942,818
        10         20         30         40         50         60 
MVEAGTRDPL ESALLDSRYL VQAKIASGGT STVYRGLDVR LDRPVALKVM DARYAGDEQF 

        70         80         90        100        110        120 
LTRFRLEARA VARLNNRALV AVYDQGKDGR HPFLVMELIE GGTLRELLIE RGPMPPHAVV 

       130        140        150        160        170        180 
AVLRPVLGGL AAAHRAGLVH RDVKPENILI SDDGDVKLAD FGLVRAVAAA SITSTGVILG 

       190        200        210        220        230        240 
TAAYLSPEQV RDGNADPRSD VYSVGVLVYE LLTGHTPFTG DSALSIAYQR LDADVPRASA 

       250        260        270        280        290        300 
VIDGVPPQFD ELVACATARN PADRYADAIA MGADLEAIAE ELALPEFRVP APRNSAQHRS 

       310        320        330        340        350        360 
AALYRSRITQ QGQLGAKPVH HPTRQLTRQP GDCSEPASGS EPEHEPITGQ FAGIAIEEFI 

       370        380        390 
WARQHARRMV LVWVSVVLAI TGLVASAAWT IGSNLSGLL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX248333 Genomic DNA. Translation: CDO43452.1.
RefSeqNP_855847.1. NC_002945.3.

3D structure databases

ProteinModelPortalQ7TYY6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING233413.Mb2198.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD97051; CAD97051; Mb2198.
GeneID1091294.
KEGGmbo:Mb2198.
PATRIC18006536. VBIMycBov88188_2414.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000037187.
KOK08884.
OMAIVENIGS.
OrthoDBEOG6B35XT.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKNL_MYCBO
AccessionPrimary (citable) accession number: Q7TYY6
Secondary accession number(s): X2BJJ4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: October 1, 2003
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families