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Q7TXA9 (PKNK_MYCBO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase PknK

EC=2.7.11.1
Alternative name(s):
Protein kinase K
Gene names
Name:pknK
Ordered Locus Names:Mb3107c
OrganismMycobacterium bovis (strain ATCC BAA-935 / AF2122/97) [Complete proteome] [HAMAP]
Taxonomic identifier233413 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex

Protein attributes

Sequence length1110 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 11101110Serine/threonine-protein kinase PknK
PRO_0000171223

Regions

Domain26 – 283258Protein kinase
Nucleotide binding32 – 409ATP By similarity

Sites

Active site1481Proton acceptor By similarity
Metal binding1541Magnesium By similarity
Metal binding1671Magnesium By similarity
Binding site551ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7TXA9 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 3C2AD79972BCCDA0

FASTA1,110119,446
        10         20         30         40         50         60 
MTDVDPHATR RDLVPNIPAE LLEAGFDNVE EIGRGGFGVV YRCVQPSLDR AVAVKVLSTD 

        70         80         90        100        110        120 
LDRDNLERFL REQRAMGRLS GHPHIVTVLQ VGVLAGGRPF IVMPYHAKNS LETLIRRHGP 

       130        140        150        160        170        180 
LDWRETLSIG VKLAGALEAA HRVGTLHRDV KPGNILLTDY GEPQLTDFGI ARIAGGFETA 

       190        200        210        220        230        240 
TGVIAGSPAF TAPEVLEGAS PTPASDVYSL GATLFCVLTG HAAYERRSGE RVIAQFLRIT 

       250        260        270        280        290        300 
SQPIPDLRKQ GLPADVAAAI ERAMARHPAD RPATAADVGE ELRDVQRRNG VSVDEMPLPV 

       310        320        330        340        350        360 
ELGVERRRSP EAHAAHRHTG GGTPTVPTPP TPATKYRPSV PTGSLVTRSR LTDILRAGGR 

       370        380        390        400        410        420 
RRLILIHAPS GFGKSTLAAQ WREELSRDGA AVAWLTIDND DNNEVWFLSH LLESIRRVRP 

       430        440        450        460        470        480 
TLAESLGHVL EEHGDDAGRY VLTSLIDEIH ENDDRIAVVI DDWHRVSDSR TQAALGFLLD 

       490        500        510        520        530        540 
NGCHHLQLIV TSWSRAGLPV GRLRIGDELA EIDSAALRFD TDEAAALLND AGGLRLPRAD 

       550        560        570        580        590        600 
VQALTTSTDG WAAALRLAAL SLRGGGDATQ LLRGLSGASD VIHEFLSENV LDTLEPELRE 

       610        620        630        640        650        660 
FLLVASVTER TCGGLASALA GITNGRAMLE EAEHRGLFLQ RTEDDPNWFR FHQMFADFLH 

       670        680        690        700        710        720 
RRLERGGSHR VAELHRRASA WFAENGYLHE AVDHALAAGD PARAVDLVEQ DETNLPEQSK 

       730        740        750        760        770        780 
MTTLLAIVQK LPTSMVVSRA RLQLAIAWAN ILLQRPAPAT GALNRFETAL GRAELPEATQ 

       790        800        810        820        830        840 
ADLRAEADVL RAVAEVFADR VERVDDLLAE AMSRPDTLPP RVPGTAGNTA ALAAICRFEF 

       850        860        870        880        890        900 
AEVYPLLDWA APYQEMMGPF GTVYAQCLRG MAARNRLDIV AALQNFRTAF EVGTAVGAHS 

       910        920        930        940        950        960 
HAARLAGSLL AELLYETGDL AGAGRLMDES YLLGSEGGAV DYLAARYVIG ARVKAAQGDH 

       970        980        990       1000       1010       1020 
EGAADRLSTG GDTAVQLGLP RLAARINNER IRLGIALPAA VAADLLAPRT IPRDNGIATM 

      1030       1040       1050       1060       1070       1080 
TAELDEDSAV RLLSAGDSAD RDQACQRAGA LAAAIDGTRR PLAALQAQIL HIETLAATGR 

      1090       1100       1110 
ESDARNELAP VATKCAELGL SRLLVDAGLA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX248333 Genomic DNA. Translation: CDO44376.1.
RefSeqNP_856752.1. NC_002945.3.

3D structure databases

ProteinModelPortalQ7TXA9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING233413.Mb3107c.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD96794; CAD96794; Mb3107c.
GeneID1093286.
KEGGmbo:Mb3107c.
PATRIC18008570. VBIMycBov88188_3414.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000074403.
KOK13419.
OMAGPLWRRS.
OrthoDBEOG69GZGV.

Family and domain databases

Gene3D1.25.40.10. 1 hit.
3.40.50.300. 1 hit.
InterProIPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR016236. Ser/Thr_kinase_PknK_prd.
IPR011990. TPR-like_helical.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
PIRSFPIRSF000574. Ser/Thr_PK_PknK_prd. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKNK_MYCBO
AccessionPrimary (citable) accession number: Q7TXA9
Secondary accession number(s): X2BNB1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: October 1, 2003
Last modified: June 11, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families