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Protein

60 kDa chaperonin 2

Gene

groL2

Organism
Prochlorococcus marinus (strain MIT 9313)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 2UniRule annotation
Alternative name(s):
GroEL protein 2UniRule annotation
Protein Cpn60 2UniRule annotation
Gene namesi
Name:groL2UniRule annotation
Synonyms:groEL2UniRule annotation
Ordered Locus Names:PMT_1449
OrganismiProchlorococcus marinus (strain MIT 9313)
Taxonomic identifieri74547 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000001423 Componenti: Chromosome

Subcellular locationi

Q7TUS4:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000634831 – 54460 kDa chaperonin 2Add BLAST544

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi74547.PMT1449.

Structurei

3D structure databases

ProteinModelPortaliQ7TUS4.
SMRiQ7TUS4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7TUS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKRIIYNEQ ARRALERGID ILAESVAVTL GPKGRNVVLE KKFGAPQIIN
60 70 80 90 100
DGVTIAKEIE LEDHIENTGV ALIRQAASKT NDAAGDGTTT ATVLAHAMVK
110 120 130 140 150
AGLRNVAAGA NAISLKKGID KASDFLVSKI EELAKPISDS NAIAQCGTIA
160 170 180 190 200
AGNDEEVGQM IADAMDKVGK EGVISLEEGK SMTTELEVTE GMRFDKGYIS
210 220 230 240 250
PYFATDTERM EAVLDEPYIL LTDKKIGLVQ DLVPVLEQIA RTGKPLLIIA
260 270 280 290 300
EDIEKEALAT LVVNRLRGVL NVAAVKAPGF GDRRKAMLED MAVLTNGQLI
310 320 330 340 350
TEDAGLKLDN AKLEMLGTAR RVTINKDTTT IVAEGNETAV KGRCEQIKKQ
360 370 380 390 400
MDETDSTYDK EKLQERLAKL AGGVAVVKVG AATETEMKDK KLRLEDAINA
410 420 430 440 450
TKAAVEEGIV PGGGTTLTHL ASDLQKWANS NLSGEELIGS NIVEASLAAP
460 470 480 490 500
LMRIAENAGA NGAVVAENVK SRPISDGYNA ATGDYIDMLA AGIVDPAKVT
510 520 530 540
RSGLQNAASI AGMVLTTECI VADLPEKKEA APAGGGGMGG DFDY
Length:544
Mass (Da):57,397
Last modified:October 1, 2003 - v1
Checksum:iE1198ABC400BB469
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX548175 Genomic DNA. Translation: CAE21624.1.
RefSeqiWP_011130817.1. NC_005071.1.

Genome annotation databases

EnsemblBacteriaiCAE21624; CAE21624; PMT_1449.
KEGGipmt:PMT_1449.

Similar proteinsi

Entry informationi

Entry nameiCH602_PROMM
AccessioniPrimary (citable) accession number: Q7TUS4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: October 1, 2003
Last modified: October 25, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families