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Q7TUP0 (Q7TUP0_PROMM) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP MF_01201 RuleBase RU000608
EC=5.1.1.1 HAMAP MF_01201 RuleBase RU000608
Gene names
Name:alr HAMAP MF_01201 EMBL CAE21938.1
Ordered Locus Names:PMT_1763
OrganismProchlorococcus marinus (strain MIT 9313) [Complete proteome] [HAMAP]
Taxonomic identifier74547 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 RuleBase RU004247 SAAS SAAS009006

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site601Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2911Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue601N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q7TUP0 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 3AA456ED43971114

FASTA39843,021
        10         20         30         40         50         60 
MRDLIAPHGD LPRGKNPEQI AKADPRQRAW VEVNPAAVEA NCRSLRRHLC ESCALMAVVK 

        70         80         90        100        110        120 
ADGYGHGALT VARAALQGGA KSLGVATLQE GIELRQAGHN APVLVLGNLT HSEDLKACLH 

       130        140        150        160        170        180 
WQLMPTLSSM REALLCQNLA DGSGRQFRIQ LKIDTGMTRL GCELKEAPML VEAIGHLNQL 

       190        200        210        220        230        240 
ELKGIYSHLA LADGDLQGKA AMVTDQQQQH FETVLRTLPE QHNGFTRHLA NSAGTLRDRG 

       250        260        270        280        290        300 
LHYDMVRVGL ALYGHSPNLQ LQGKVDLQPA LSVKARVTLI RDVPAGVGVS YGHRFTTRRP 

       310        320        330        340        350        360 
SRLAVVGIGY ADGVSRSLSG QISAIADGQL LPQVGAITMD QLVLDATNHP DLEVGSIVTL 

       370        380        390 
LGKDGDACIT PQQWSDLSGS IPWEVLCSFK HRLPRLVI

« Hide

References

[1]"Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation."
Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A., Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L., Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C. expand/collapse author list , Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R., Chisholm S.W.
Nature 424:1042-1047(2003) [PubMed: 12917642] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX548175 Genomic DNA. Translation: CAE21938.1.
RefSeqNP_895590.1. NC_005071.1.

3D structure databases

HSSPHSSP built from PDB template 1NIU based on UniProtKB P10724.
ProteinModelPortalQ7TUP0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ7TUP0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1729151.
GenomeReviewsGene locus PMT_1763 in contig BX548175_GR.
KEGGpmt:PMT1763.
NMPDRfig|74547.1.peg.1757.
PATRIC23012279. VBIProMar135351_2271.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHBG712172.
OMATRKEDAN.
PhylomeDBQ7TUP0.
ProtClustDBPRK00053.

Enzyme and pathway databases

BioCycPMAR74547:PMT1763-MONOMER.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ7TUP0_PROMM
AccessionPrimary (citable) accession number: Q7TUP0
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info