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Q7TST7

- Q7TST7_MOUSE

UniProt

Q7TST7 - Q7TST7_MOUSE

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Protein
Submitted name:

Protein kinase C-zeta 2

Gene
Prkcz, Prkcz2
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotations

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein binding Source: MGI
  3. protein kinase activity Source: MGI
  4. protein serine/threonine kinase activity Source: UniProtKB-KW
  5. zinc ion binding Source: InterPro

GO - Biological processi

  1. microtubule cytoskeleton organization Source: MGI
  2. neuron projection extension Source: MGI
  3. protein localization to plasma membrane Source: MGI
  4. protein phosphorylation Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseSAAS annotations, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Protein kinase C-zeta 2Imported
Gene namesi
Name:PrkczImported
Synonyms:Prkcz2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97602. Prkcz.

Subcellular locationi

GO - Cellular componenti

  1. apical cortex Source: MGI
  2. apical plasma membrane Source: MGI
  3. axon hillock Source: MGI
  4. cell cortex Source: MGI
  5. cytoplasm Source: MGI
  6. microtubule organizing center Source: MGI
  7. nuclear envelope Source: MGI
  8. nuclear matrix Source: MGI
  9. nucleus Source: MGI
  10. plasma membrane Source: MGI
  11. protein complex Source: MGI
  12. tight junction Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ7TST7.

Structurei

3D structure databases

ProteinModelPortaliQ7TST7.
SMRiQ7TST7. Positions 64-401.

Family & Domainsi

Sequence similaritiesi

Contains AGC-kinase C-terminal domain.SAAS annotations

Phylogenomic databases

HOVERGENiHBG108317.
InParanoidiQ7TST7.

Family and domain databases

InterProiIPR000961. AGC-kinase_C.
IPR011009. Kinase-like_dom.
IPR012233. PKC_zeta.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERiPTHR24357:SF60. PTHR24357:SF60. 1 hit.
PfamiPF00069. Pkinase. 1 hit.
PF00433. Pkinase_C. 1 hit.
[Graphical view]
SMARTiSM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51285. AGC_KINASE_CTER. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TST7-1 [UniParc]FASTAAdd to Basket

« Hide

MDSVMPSQEP PVDGKNDGVD LPSEETDGIA YISSSRKHDN IKDDSEDLKP    50
VIDGVDGIKI SQGLGLQDFD LIRVIGRGSY AKVLLVRLKK NDQIYAMKVV 100
KKELVHDDED IDWVQTEKHV FEQASSNPFL VGLHSCFQTT SRLFLVIEYV 150
NGGDLMFHMQ RQRKLPEEHA RFYAAEICIA LNFLHERGII YRDLKLDNVL 200
LDADGHIKLT DYGMCKEGLG PGDTTSTFCG TPNYIAPEIL RGEEYGFSVD 250
WWALGVLMFE MMAGRSPFDI ITDNPDMNTE DYLFQVILEK PIRIPRFLSV 300
KASHVLKGFL NKDPKERLGC RPQTGFSDIK SHAFFRSIDW DLLEKKQTLP 350
PFQPQITDDY GLDNFDTQFT SEPVQLTPDD EDVIKRIDQS EFEGFEYINP 400
LLLSAEESV 409
Length:409
Mass (Da):46,543
Last modified:October 1, 2003 - v1
Checksum:i628DD31702F040DE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB110830 mRNA. Translation: BAC76975.1.
UniGeneiMm.28561.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB110830 mRNA. Translation: BAC76975.1 .
UniGenei Mm.28561.

3D structure databases

ProteinModelPortali Q7TST7.
SMRi Q7TST7. Positions 64-401.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:97602. Prkcz.

Phylogenomic databases

HOVERGENi HBG108317.
InParanoidi Q7TST7.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Genevestigatori Q7TST7.

Family and domain databases

InterProi IPR000961. AGC-kinase_C.
IPR011009. Kinase-like_dom.
IPR012233. PKC_zeta.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
PANTHERi PTHR24357:SF60. PTHR24357:SF60. 1 hit.
Pfami PF00069. Pkinase. 1 hit.
PF00433. Pkinase_C. 1 hit.
[Graphical view ]
SMARTi SM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51285. AGC_KINASE_CTER. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "PKC zeta II, a small molecule of protein kinase C zeta, specifically expressed in the mouse brain."
    Hirai T., Niino Y.S., Chida K.
    Neurosci. Lett. 348:151-154(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ7TST7_MOUSE
AccessioniPrimary (citable) accession number: Q7TST7
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: September 3, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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