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Protein

Non-specific serine/threonine protein kinase

Gene

Prkcz

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific serine/threonine protein kinaseSAAS annotation (EC:2.7.11.1SAAS annotation)
Gene namesi
Name:PrkczImported
Synonyms:Prkcz2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97602 Prkcz

Interactioni

Protein-protein interaction databases

IntActiQ7TST7, 2 interactors

Structurei

3D structure databases

ProteinModelPortaliQ7TST7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini69 – 335Protein kinaseInterPro annotationAdd BLAST267
Domaini336 – 407AGC-kinase C-terminalInterPro annotationAdd BLAST72

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0695 Eukaryota
ENOG410ZMG2 LUCA
HOVERGENiHBG108317

Family and domain databases

InterProiView protein in InterPro
IPR000961 AGC-kinase_C
IPR011009 Kinase-like_dom_sf
IPR017892 Pkinase_C
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
PF00433 Pkinase_C, 1 hit
SMARTiView protein in SMART
SM00133 S_TK_X, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q7TST7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSVMPSQEP PVDGKNDGVD LPSEETDGIA YISSSRKHDN IKDDSEDLKP
60 70 80 90 100
VIDGVDGIKI SQGLGLQDFD LIRVIGRGSY AKVLLVRLKK NDQIYAMKVV
110 120 130 140 150
KKELVHDDED IDWVQTEKHV FEQASSNPFL VGLHSCFQTT SRLFLVIEYV
160 170 180 190 200
NGGDLMFHMQ RQRKLPEEHA RFYAAEICIA LNFLHERGII YRDLKLDNVL
210 220 230 240 250
LDADGHIKLT DYGMCKEGLG PGDTTSTFCG TPNYIAPEIL RGEEYGFSVD
260 270 280 290 300
WWALGVLMFE MMAGRSPFDI ITDNPDMNTE DYLFQVILEK PIRIPRFLSV
310 320 330 340 350
KASHVLKGFL NKDPKERLGC RPQTGFSDIK SHAFFRSIDW DLLEKKQTLP
360 370 380 390 400
PFQPQITDDY GLDNFDTQFT SEPVQLTPDD EDVIKRIDQS EFEGFEYINP

LLLSAEESV
Length:409
Mass (Da):46,543
Last modified:October 1, 2003 - v1
Checksum:i628DD31702F040DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB110830 mRNA Translation: BAC76975.1
UniGeneiMm.28561

Similar proteinsi

Entry informationi

Entry nameiQ7TST7_MOUSE
AccessioniPrimary (citable) accession number: Q7TST7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: March 28, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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