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Protein
Submitted name:

Protein kinase C-zeta 2

Gene

Prkcz

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Protein kinase C-zeta 2Imported
Gene namesi
Name:PrkczImported
Synonyms:Prkcz2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97602. Prkcz.

PTM / Processingi

Proteomic databases

PaxDbiQ7TST7.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030922.

Structurei

3D structure databases

ProteinModelPortaliQ7TST7.
SMRiQ7TST7. Positions 64-401.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini69 – 335267Protein kinaseInterPro annotationAdd
BLAST
Domaini336 – 40772AGC-kinase C-terminalInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation
Contains AGC-kinase C-terminal domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG0695. Eukaryota.
ENOG410ZMG2. LUCA.
HOVERGENiHBG108317.

Family and domain databases

InterProiIPR000961. AGC-kinase_C.
IPR011009. Kinase-like_dom.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
PF00433. Pkinase_C. 1 hit.
[Graphical view]
SMARTiSM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51285. AGC_KINASE_CTER. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TST7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSVMPSQEP PVDGKNDGVD LPSEETDGIA YISSSRKHDN IKDDSEDLKP
60 70 80 90 100
VIDGVDGIKI SQGLGLQDFD LIRVIGRGSY AKVLLVRLKK NDQIYAMKVV
110 120 130 140 150
KKELVHDDED IDWVQTEKHV FEQASSNPFL VGLHSCFQTT SRLFLVIEYV
160 170 180 190 200
NGGDLMFHMQ RQRKLPEEHA RFYAAEICIA LNFLHERGII YRDLKLDNVL
210 220 230 240 250
LDADGHIKLT DYGMCKEGLG PGDTTSTFCG TPNYIAPEIL RGEEYGFSVD
260 270 280 290 300
WWALGVLMFE MMAGRSPFDI ITDNPDMNTE DYLFQVILEK PIRIPRFLSV
310 320 330 340 350
KASHVLKGFL NKDPKERLGC RPQTGFSDIK SHAFFRSIDW DLLEKKQTLP
360 370 380 390 400
PFQPQITDDY GLDNFDTQFT SEPVQLTPDD EDVIKRIDQS EFEGFEYINP

LLLSAEESV
Length:409
Mass (Da):46,543
Last modified:October 1, 2003 - v1
Checksum:i628DD31702F040DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB110830 mRNA. Translation: BAC76975.1.
UniGeneiMm.28561.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB110830 mRNA. Translation: BAC76975.1.
UniGeneiMm.28561.

3D structure databases

ProteinModelPortaliQ7TST7.
SMRiQ7TST7. Positions 64-401.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030922.

Proteomic databases

PaxDbiQ7TST7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:97602. Prkcz.

Phylogenomic databases

eggNOGiKOG0695. Eukaryota.
ENOG410ZMG2. LUCA.
HOVERGENiHBG108317.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

InterProiIPR000961. AGC-kinase_C.
IPR011009. Kinase-like_dom.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
PF00433. Pkinase_C. 1 hit.
[Graphical view]
SMARTiSM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51285. AGC_KINASE_CTER. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "PKC zeta II, a small molecule of protein kinase C zeta, specifically expressed in the mouse brain."
    Hirai T., Niino Y.S., Chida K.
    Neurosci. Lett. 348:151-154(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ7TST7_MOUSE
AccessioniPrimary (citable) accession number: Q7TST7
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: May 11, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.