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Protein

Probable G-protein coupled receptor 151 protein

Gene

Gpr151

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Probable G-protein coupled receptor 151 protein
Alternative name(s):
G-protein coupled receptor PGR7
GPCR-2037
Gene namesi
Name:Gpr151
Synonyms:Pgr7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:2441887. Gpr151.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 45ExtracellularSequence analysisAdd BLAST45
Transmembranei46 – 66Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini67 – 76CytoplasmicSequence analysis10
Transmembranei77 – 97Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini98 – 123ExtracellularSequence analysisAdd BLAST26
Transmembranei124 – 144Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini145 – 157CytoplasmicSequence analysisAdd BLAST13
Transmembranei158 – 178Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini179 – 205ExtracellularSequence analysisAdd BLAST27
Transmembranei206 – 226Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini227 – 259CytoplasmicSequence analysisAdd BLAST33
Transmembranei260 – 280Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini281 – 290ExtracellularSequence analysis10
Transmembranei291 – 311Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini312 – 422CytoplasmicSequence analysisAdd BLAST111

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000696331 – 422Probable G-protein coupled receptor 151 proteinAdd BLAST422

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi14N-linked (GlcNAc...)Sequence analysis1
Glycosylationi19N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi115 ↔ 191PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ7TSN6.
PRIDEiQ7TSN6.

PTM databases

PhosphoSitePlusiQ7TSN6.

Expressioni

Gene expression databases

BgeeiENSMUSG00000042816.
CleanExiMM_GPR151.
GenevisibleiQ7TSN6. MM.

Interactioni

Protein-protein interaction databases

IntActiQ7TSN6. 1 interactor.
STRINGi10090.ENSMUSP00000058887.

Structurei

3D structure databases

ProteinModelPortaliQ7TSN6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00640000091572.
HOGENOMiHOG000112774.
HOVERGENiHBG051787.
InParanoidiQ7TSN6.
KOiK08435.
OMAiCKSSDWF.
OrthoDBiEOG091G09J0.
PhylomeDBiQ7TSN6.
TreeFamiTF332591.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TSN6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKAMLRAGF ADTNSSNMNE SFARLHFAGG YLPSDSKDWR TIIPSLLMAV
60 70 80 90 100
CLVGLVGNLC VIGILLHGVW KRKPSTIHSL ILNLSLADFS LLLFSAPVRA
110 120 130 140 150
AAYSKGVWDL GWFICKSSDW FTHVCMAAKS LTFVVVAKAC FAYASDPAKQ
160 170 180 190 200
ESIHSRTIWS VLAGIWVVAS LLPLPEWLFS TTRRHAGVEM CLVDVPAVAE
210 220 230 240 250
EFMSMFGKLY PLLVFCLPLL LAGVYFWRAY DQCKTRCTKT RNLRDQMRSK
260 270 280 290 300
QLTVMLLSTA IISALLWLPE WIAWLWVWHV KAGGPMPPQG FIALSQVLMF
310 320 330 340 350
FTSTANPLIF LVMSEEFKAG LKGLWKWMIT RKPAVTSEVQ EAPAGNTEAL
360 370 380 390 400
PGKAPSPETQ TCILDTDGRG SPDDSKEKSG KVVAPILPDV EQFWHERDAV
410 420
PSAQDNDPIP WEHEGQETEG CN
Length:422
Mass (Da):46,826
Last modified:October 1, 2003 - v1
Checksum:i06F6F2FB2127793F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ564167 mRNA. Translation: CAD91896.1.
BC120520 mRNA. Translation: AAI20521.1.
BC120526 mRNA. Translation: AAI20527.1.
AY351677 mRNA. Translation: AAQ62568.1.
AK048591 mRNA. Translation: BAC33383.1.
AY255533 mRNA. Translation: AAO85045.1.
CCDSiCCDS29215.1.
RefSeqiNP_853521.1. NM_181543.1.
UniGeneiMm.186779.

Genome annotation databases

EnsembliENSMUST00000054738; ENSMUSP00000058887; ENSMUSG00000042816.
GeneIDi240239.
KEGGimmu:240239.
UCSCiuc008eua.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ564167 mRNA. Translation: CAD91896.1.
BC120520 mRNA. Translation: AAI20521.1.
BC120526 mRNA. Translation: AAI20527.1.
AY351677 mRNA. Translation: AAQ62568.1.
AK048591 mRNA. Translation: BAC33383.1.
AY255533 mRNA. Translation: AAO85045.1.
CCDSiCCDS29215.1.
RefSeqiNP_853521.1. NM_181543.1.
UniGeneiMm.186779.

3D structure databases

ProteinModelPortaliQ7TSN6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ7TSN6. 1 interactor.
STRINGi10090.ENSMUSP00000058887.

PTM databases

PhosphoSitePlusiQ7TSN6.

Proteomic databases

PaxDbiQ7TSN6.
PRIDEiQ7TSN6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000054738; ENSMUSP00000058887; ENSMUSG00000042816.
GeneIDi240239.
KEGGimmu:240239.
UCSCiuc008eua.1. mouse.

Organism-specific databases

CTDi134391.
MGIiMGI:2441887. Gpr151.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00640000091572.
HOGENOMiHOG000112774.
HOVERGENiHBG051787.
InParanoidiQ7TSN6.
KOiK08435.
OMAiCKSSDWF.
OrthoDBiEOG091G09J0.
PhylomeDBiQ7TSN6.
TreeFamiTF332591.

Miscellaneous databases

PROiQ7TSN6.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000042816.
CleanExiMM_GPR151.
GenevisibleiQ7TSN6. MM.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGP151_MOUSE
AccessioniPrimary (citable) accession number: Q7TSN6
Secondary accession number(s): Q0VBS2, Q80UD8, Q8BX88
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: October 1, 2003
Last modified: November 2, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.