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Q7TSN6

- GP151_MOUSE

UniProt

Q7TSN6 - GP151_MOUSE

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Protein
Probable G-protein coupled receptor 151 protein
Gene
Gpr151, Pgr7
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Probable G-protein coupled receptor 151 protein
Alternative name(s):
G-protein coupled receptor PGR7
GPCR-2037
Gene namesi
Name:Gpr151
Synonyms:Pgr7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 18

Organism-specific databases

MGIiMGI:2441887. Gpr151.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 4545Extracellular Reviewed prediction
Add
BLAST
Transmembranei46 – 6621Helical; Name=1; Reviewed prediction
Add
BLAST
Topological domaini67 – 7610Cytoplasmic Reviewed prediction
Transmembranei77 – 9721Helical; Name=2; Reviewed prediction
Add
BLAST
Topological domaini98 – 12326Extracellular Reviewed prediction
Add
BLAST
Transmembranei124 – 14421Helical; Name=3; Reviewed prediction
Add
BLAST
Topological domaini145 – 15713Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei158 – 17821Helical; Name=4; Reviewed prediction
Add
BLAST
Topological domaini179 – 20527Extracellular Reviewed prediction
Add
BLAST
Transmembranei206 – 22621Helical; Name=5; Reviewed prediction
Add
BLAST
Topological domaini227 – 25933Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei260 – 28021Helical; Name=6; Reviewed prediction
Add
BLAST
Topological domaini281 – 29010Extracellular Reviewed prediction
Transmembranei291 – 31121Helical; Name=7; Reviewed prediction
Add
BLAST
Topological domaini312 – 422111Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 422422Probable G-protein coupled receptor 151 protein
PRO_0000069633Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi14 – 141N-linked (GlcNAc...) Reviewed prediction
Glycosylationi19 – 191N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi115 ↔ 191 By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiQ7TSN6.

PTM databases

PhosphoSiteiQ7TSN6.

Expressioni

Gene expression databases

BgeeiQ7TSN6.
CleanExiMM_GPR151.
GenevestigatoriQ7TSN6.

Structurei

3D structure databases

ProteinModelPortaliQ7TSN6.
SMRiQ7TSN6. Positions 42-324.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG288736.
GeneTreeiENSGT00640000091572.
HOGENOMiHOG000112774.
HOVERGENiHBG051787.
InParanoidiQ0VBS2.
KOiK08435.
OMAiCKSSDWF.
OrthoDBiEOG74FF0X.
PhylomeDBiQ7TSN6.
TreeFamiTF332591.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TSN6-1 [UniParc]FASTAAdd to Basket

« Hide

MGKAMLRAGF ADTNSSNMNE SFARLHFAGG YLPSDSKDWR TIIPSLLMAV    50
CLVGLVGNLC VIGILLHGVW KRKPSTIHSL ILNLSLADFS LLLFSAPVRA 100
AAYSKGVWDL GWFICKSSDW FTHVCMAAKS LTFVVVAKAC FAYASDPAKQ 150
ESIHSRTIWS VLAGIWVVAS LLPLPEWLFS TTRRHAGVEM CLVDVPAVAE 200
EFMSMFGKLY PLLVFCLPLL LAGVYFWRAY DQCKTRCTKT RNLRDQMRSK 250
QLTVMLLSTA IISALLWLPE WIAWLWVWHV KAGGPMPPQG FIALSQVLMF 300
FTSTANPLIF LVMSEEFKAG LKGLWKWMIT RKPAVTSEVQ EAPAGNTEAL 350
PGKAPSPETQ TCILDTDGRG SPDDSKEKSG KVVAPILPDV EQFWHERDAV 400
PSAQDNDPIP WEHEGQETEG CN 422
Length:422
Mass (Da):46,826
Last modified:October 1, 2003 - v1
Checksum:i06F6F2FB2127793F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ564167 mRNA. Translation: CAD91896.1.
BC120520 mRNA. Translation: AAI20521.1.
BC120526 mRNA. Translation: AAI20527.1.
AY351677 mRNA. Translation: AAQ62568.1.
AK048591 mRNA. Translation: BAC33383.1.
AY255533 mRNA. Translation: AAO85045.1.
CCDSiCCDS29215.1.
RefSeqiNP_853521.1. NM_181543.1.
UniGeneiMm.186779.

Genome annotation databases

EnsembliENSMUST00000054738; ENSMUSP00000058887; ENSMUSG00000042816.
GeneIDi240239.
KEGGimmu:240239.
UCSCiuc008eua.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ564167 mRNA. Translation: CAD91896.1 .
BC120520 mRNA. Translation: AAI20521.1 .
BC120526 mRNA. Translation: AAI20527.1 .
AY351677 mRNA. Translation: AAQ62568.1 .
AK048591 mRNA. Translation: BAC33383.1 .
AY255533 mRNA. Translation: AAO85045.1 .
CCDSi CCDS29215.1.
RefSeqi NP_853521.1. NM_181543.1.
UniGenei Mm.186779.

3D structure databases

ProteinModelPortali Q7TSN6.
SMRi Q7TSN6. Positions 42-324.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q7TSN6.

Proteomic databases

PRIDEi Q7TSN6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000054738 ; ENSMUSP00000058887 ; ENSMUSG00000042816 .
GeneIDi 240239.
KEGGi mmu:240239.
UCSCi uc008eua.1. mouse.

Organism-specific databases

CTDi 134391.
MGIi MGI:2441887. Gpr151.

Phylogenomic databases

eggNOGi NOG288736.
GeneTreei ENSGT00640000091572.
HOGENOMi HOG000112774.
HOVERGENi HBG051787.
InParanoidi Q0VBS2.
KOi K08435.
OMAi CKSSDWF.
OrthoDBi EOG74FF0X.
PhylomeDBi Q7TSN6.
TreeFami TF332591.

Miscellaneous databases

NextBioi 384518.
PROi Q7TSN6.
SOURCEi Search...

Gene expression databases

Bgeei Q7TSN6.
CleanExi MM_GPR151.
Genevestigatori Q7TSN6.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view ]
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PROSITEi PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning of a novel orphan G protein-coupled receptor (GPCR-2037): in situ hybridization reveals high mRNA expression in rat brain restricted to neurons of the habenular complex."
    Berthold M., Collin M., Sejlitz T., Meister B., Lind P.
    Brain Res. Mol. Brain Res. 120:22-29(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: BALB/c.
    Tissue: Brain.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  3. "Molecular cloning of a novel G-protein-coupled receptor."
    Ignatov A., Schaller H.C.
    Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 5-422.
    Strain: C3H/He.
  4. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 102-422.
    Strain: C57BL/6J.
    Tissue: Head.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 45-158.

Entry informationi

Entry nameiGP151_MOUSE
AccessioniPrimary (citable) accession number: Q7TSN6
Secondary accession number(s): Q0VBS2, Q80UD8, Q8BX88
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: October 1, 2003
Last modified: July 9, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

External Data

Dasty 3

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