Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q7TSN6

- GP151_MOUSE

UniProt

Q7TSN6 - GP151_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable G-protein coupled receptor 151 protein

Gene

Gpr151

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Probable G-protein coupled receptor 151 protein
Alternative name(s):
G-protein coupled receptor PGR7
GPCR-2037
Gene namesi
Name:Gpr151
Synonyms:Pgr7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 18

Organism-specific databases

MGIiMGI:2441887. Gpr151.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 422422Probable G-protein coupled receptor 151 proteinPRO_0000069633Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi14 – 141N-linked (GlcNAc...)Sequence Analysis
Glycosylationi19 – 191N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi115 ↔ 191PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiQ7TSN6.

PTM databases

PhosphoSiteiQ7TSN6.

Expressioni

Gene expression databases

BgeeiQ7TSN6.
CleanExiMM_GPR151.
GenevestigatoriQ7TSN6.

Structurei

3D structure databases

ProteinModelPortaliQ7TSN6.
SMRiQ7TSN6. Positions 42-324.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 4545ExtracellularSequence AnalysisAdd
BLAST
Topological domaini67 – 7610CytoplasmicSequence Analysis
Topological domaini98 – 12326ExtracellularSequence AnalysisAdd
BLAST
Topological domaini145 – 15713CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini179 – 20527ExtracellularSequence AnalysisAdd
BLAST
Topological domaini227 – 25933CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini281 – 29010ExtracellularSequence Analysis
Topological domaini312 – 422111CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei46 – 6621Helical; Name=1Sequence AnalysisAdd
BLAST
Transmembranei77 – 9721Helical; Name=2Sequence AnalysisAdd
BLAST
Transmembranei124 – 14421Helical; Name=3Sequence AnalysisAdd
BLAST
Transmembranei158 – 17821Helical; Name=4Sequence AnalysisAdd
BLAST
Transmembranei206 – 22621Helical; Name=5Sequence AnalysisAdd
BLAST
Transmembranei260 – 28021Helical; Name=6Sequence AnalysisAdd
BLAST
Transmembranei291 – 31121Helical; Name=7Sequence AnalysisAdd
BLAST

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG288736.
GeneTreeiENSGT00640000091572.
HOGENOMiHOG000112774.
HOVERGENiHBG051787.
InParanoidiQ7TSN6.
KOiK08435.
OMAiCKSSDWF.
OrthoDBiEOG74FF0X.
PhylomeDBiQ7TSN6.
TreeFamiTF332591.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TSN6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGKAMLRAGF ADTNSSNMNE SFARLHFAGG YLPSDSKDWR TIIPSLLMAV
60 70 80 90 100
CLVGLVGNLC VIGILLHGVW KRKPSTIHSL ILNLSLADFS LLLFSAPVRA
110 120 130 140 150
AAYSKGVWDL GWFICKSSDW FTHVCMAAKS LTFVVVAKAC FAYASDPAKQ
160 170 180 190 200
ESIHSRTIWS VLAGIWVVAS LLPLPEWLFS TTRRHAGVEM CLVDVPAVAE
210 220 230 240 250
EFMSMFGKLY PLLVFCLPLL LAGVYFWRAY DQCKTRCTKT RNLRDQMRSK
260 270 280 290 300
QLTVMLLSTA IISALLWLPE WIAWLWVWHV KAGGPMPPQG FIALSQVLMF
310 320 330 340 350
FTSTANPLIF LVMSEEFKAG LKGLWKWMIT RKPAVTSEVQ EAPAGNTEAL
360 370 380 390 400
PGKAPSPETQ TCILDTDGRG SPDDSKEKSG KVVAPILPDV EQFWHERDAV
410 420
PSAQDNDPIP WEHEGQETEG CN
Length:422
Mass (Da):46,826
Last modified:October 1, 2003 - v1
Checksum:i06F6F2FB2127793F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ564167 mRNA. Translation: CAD91896.1.
BC120520 mRNA. Translation: AAI20521.1.
BC120526 mRNA. Translation: AAI20527.1.
AY351677 mRNA. Translation: AAQ62568.1.
AK048591 mRNA. Translation: BAC33383.1.
AY255533 mRNA. Translation: AAO85045.1.
CCDSiCCDS29215.1.
RefSeqiNP_853521.1. NM_181543.1.
UniGeneiMm.186779.

Genome annotation databases

EnsembliENSMUST00000054738; ENSMUSP00000058887; ENSMUSG00000042816.
GeneIDi240239.
KEGGimmu:240239.
UCSCiuc008eua.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ564167 mRNA. Translation: CAD91896.1 .
BC120520 mRNA. Translation: AAI20521.1 .
BC120526 mRNA. Translation: AAI20527.1 .
AY351677 mRNA. Translation: AAQ62568.1 .
AK048591 mRNA. Translation: BAC33383.1 .
AY255533 mRNA. Translation: AAO85045.1 .
CCDSi CCDS29215.1.
RefSeqi NP_853521.1. NM_181543.1.
UniGenei Mm.186779.

3D structure databases

ProteinModelPortali Q7TSN6.
SMRi Q7TSN6. Positions 42-324.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q7TSN6.

Proteomic databases

PRIDEi Q7TSN6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000054738 ; ENSMUSP00000058887 ; ENSMUSG00000042816 .
GeneIDi 240239.
KEGGi mmu:240239.
UCSCi uc008eua.1. mouse.

Organism-specific databases

CTDi 134391.
MGIi MGI:2441887. Gpr151.

Phylogenomic databases

eggNOGi NOG288736.
GeneTreei ENSGT00640000091572.
HOGENOMi HOG000112774.
HOVERGENi HBG051787.
InParanoidi Q7TSN6.
KOi K08435.
OMAi CKSSDWF.
OrthoDBi EOG74FF0X.
PhylomeDBi Q7TSN6.
TreeFami TF332591.

Miscellaneous databases

NextBioi 384518.
PROi Q7TSN6.
SOURCEi Search...

Gene expression databases

Bgeei Q7TSN6.
CleanExi MM_GPR151.
Genevestigatori Q7TSN6.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view ]
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PROSITEi PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning of a novel orphan G protein-coupled receptor (GPCR-2037): in situ hybridization reveals high mRNA expression in rat brain restricted to neurons of the habenular complex."
    Berthold M., Collin M., Sejlitz T., Meister B., Lind P.
    Brain Res. Mol. Brain Res. 120:22-29(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: BALB/c.
    Tissue: Brain.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  3. "Molecular cloning of a novel G-protein-coupled receptor."
    Ignatov A., Schaller H.C.
    Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 5-422.
    Strain: C3H/He.
  4. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 102-422.
    Strain: C57BL/6J.
    Tissue: Head.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 45-158.

Entry informationi

Entry nameiGP151_MOUSE
AccessioniPrimary (citable) accession number: Q7TSN6
Secondary accession number(s): Q0VBS2, Q80UD8, Q8BX88
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: October 1, 2003
Last modified: October 29, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

External Data

Dasty 3