Unreviewed,
UniProtKB/TrEMBL Q7TSI6 (Q7TSI6_MOUSE)
Last modified
January 19, 2010.
Version 57.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information
Names and origin
| Protein names | Submitted name: Vav2 protein EMBL AAH53060.1 | ||
| Gene names |
| ||
| Organism | Mus musculus (Mouse) EMBL AAH53060.1 | ||
| Taxonomic identifier | 10090 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus |
Protein attributes
| Sequence length | 829 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Sequence similarities | Contains 1 DH (DBL-homology) domain. Contains 1 PH domain. |
Ontologies
| Keywords | |
|---|---|
| Ligand | Metal-binding Spearmint SPM002219 Zinc Spearmint SPM002219 |
| Gene Ontology (GO) | |
| Biological process | intracellular signaling cascade Inferred from electronic annotation. Source: InterPro regulation of Rho protein signal transductionInferred from electronic annotation. Source: InterPro |
| Cellular component | intracellular Inferred from electronic annotation. Source: InterPro |
| Molecular function | Rho guanyl-nucleotide exchange factor activity Inferred from electronic annotation. Source: InterPro protein bindingInferred from electronic annotation. Source: InterPro zinc ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequences
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References
| [1] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6 EMBL AAH53060.1. Tissue: Brain EMBL AAH53060.1. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BC053060 mRNA. Translation: AAH53060.1. |
| IPI | IPI00272559. |
| UniGene | Mm.179011 |
3D structure databases | |
| HSSP | HSSP built from PDB template 1F5X based on UniProtKB P27870. |
| SMR | Q7TSI6. Positions 1-95, 128-339, 481-534, 551-706. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q7TSI6. |
Proteomic databases | |
| PRIDE | Q7TSI6. |
Genome annotation databases | |
| Ensembl | ENSMUST00000009765; ENSMUSP00000009765; ENSMUSG00000009621; Mus musculus. [Genome view] |
Organism-specific databases | |
| MGI | MGI:102718. Vav2. |
Phylogenomic databases | |
| HOVERGEN | Q7TSI6. |
Gene expression databases | |
| ArrayExpress | Q7TSI6. |
| Bgee | Q7TSI6. |
| Genevestigator | Q7TSI6. |
Family and domain databases | |
| InterPro | IPR016146. Calponin-homology. IPR001715. Calponin_act_bd. IPR000219. DH-domain. IPR001331. GDS_CDC24_CS. IPR001849. Pleckstrin_homology. IPR002219. Prot_Kinase_C-like_PE/DAG_bd. IPR000980. SH2. IPR011511. SH3_2. IPR001452. SH3_domain. [Graphical view] |
| Gene3D | G3DSA:1.10.418.10. Calponin-homology. 1 hit. G3DSA:1.20.900.10. RhoGEF. 1 hit. G3DSA:3.30.505.10. SH2. 1 hit. |
| Pfam | PF00130. C1_1. 1 hit. PF00169. PH. 1 hit. PF00621. RhoGEF. 1 hit. PF00017. SH2. 1 hit. PF07653. SH3_2. 1 hit. [Graphical view] |
| SMART | SM00109. C1. 1 hit. SM00033. CH. 1 hit. SM00233. PH. 1 hit. SM00325. RhoGEF. 1 hit. SM00252. SH2. 1 hit. SM00326. SH3. 1 hit. [Graphical view] |
| PROSITE | PS50021. CH. 1 hit. PS00741. DH_1. 1 hit. PS50010. DH_2. 1 hit. PS50003. PH_DOMAIN. 1 hit. PS50001. SH2. 1 hit. PS50002. SH3. 1 hit. PS00479. ZF_DAG_PE_1. 1 hit. PS50081. ZF_DAG_PE_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| SOURCE | Search... |
Entry information
| Entry name | Q7TSI6_MOUSE | ||||||||
| Accession | Primary (citable) accession number: Q7TSI6 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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