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Protein
Submitted name:

Mki67 protein

Gene

Mki67

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cell proliferation Source: MGI
  • cholangiocyte proliferation Source: MGI
  • hepatocyte proliferation Source: MGI
  • meiotic nuclear division Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Mki67 proteinImported
Gene namesi
Name:Mki67Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:106035. Mki67.

Subcellular locationi

GO - Cellular componenti

  • chromosome, centromeric region Source: MGI
  • condensed chromosome Source: MGI
  • cytoplasm Source: MGI
  • membrane Source: MGI
  • nucleolus Source: MGI
  • nucleus Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ7TSF6.

Expressioni

Gene expression databases

BgeeiQ7TSF6.
GenevisibleiQ7TSF6. MM.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ7TSF6. 17 interactions.
STRINGi10090.ENSMUSP00000033310.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410JR7C. Eukaryota.
ENOG410ZXYW. LUCA.
KOiK17582.
PhylomeDBiQ7TSF6.

Family and domain databases

InterProiIPR012568. K167R.
[Graphical view]
PfamiPF08065. K167R. 3 hits.
[Graphical view]
SMARTiSM01295. K167R. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TSF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSVIVEKTP KMPDKSPEPV DTTSETQARR RLRRLVVTEE PIPQRKTTRV
60 70 80 90 100
VRQTRNTQKE PISDNQGMEE FKESSVQKQD PSVSLTGRRN QPRTVKEKTQ
110 120 130 140 150
PLEELTSFQE ETAKRISSKS PQPEEKETLA GLKRQLRIQL INDGVKEEPT
160 170 180 190 200
AQRKQPSRET RNTLKEPVGD SINVEEVKKS TKQKIDPVAS VPVSKRPRRV
210 220 230 240 250
PKEKAQALEL AGLKGPIQTL GHTDESASDK GPTQMPCNSL QPEQVDSFQS
260 270 280 290 300
SPRRPRTRRG KVEADEEPSA VRKTVSTSRQ TMRSRKVPEI GNNGTQVSKA
310 320 330 340 350
SIKQTLDTVA KVTGSRRQLR THKDGVQPLE VLGDSKEITQ ISDHSEKLAH
360 370 380 390 400
DTSILKSTQQ QKPDSVKPLR TCRRVLRASK EDPKEVLVDT RDHATLQSKS
410 420 430 440 450
NPLLSPKRKS ARDGSIVRTR ALRSLAPKQE ATDEKPVPEK KRAASSKRHV
460 470 480 490 500
SPEPVKMKHL KIVSNKLESV EEQVSTVMKT EEMEAKRENP VTPDQNSRYR
510 520 530 540 550
KKTNVKQPRP KFDASAENVG IKKNEKTMKT ASQETELQNP DDGAKKSTSR
560 570 580 590 600
GQVSGKRTCL RSRGTTEMPQ PCEAEEKTSK PAAEILIKPQ EEKGVSGESD
610 620 630 640
VRCLRSRKTR VALDSEPKPR VTRGTKKDAK TLKEDEDIVC TKKLRTRS
Length:648
Mass (Da):72,796
Last modified:October 1, 2003 - v1
Checksum:iF9825DD4B9C2F837
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC053453 mRNA. Translation: AAH53453.1.
RefSeqiNP_001074586.2. NM_001081117.2.
UniGeneiMm.4078.

Genome annotation databases

GeneIDi17345.
KEGGimmu:17345.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC053453 mRNA. Translation: AAH53453.1.
RefSeqiNP_001074586.2. NM_001081117.2.
UniGeneiMm.4078.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ7TSF6. 17 interactions.
STRINGi10090.ENSMUSP00000033310.

Proteomic databases

PaxDbiQ7TSF6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi17345.
KEGGimmu:17345.

Organism-specific databases

CTDi4288.
MGIiMGI:106035. Mki67.

Phylogenomic databases

eggNOGiENOG410JR7C. Eukaryota.
ENOG410ZXYW. LUCA.
KOiK17582.
PhylomeDBiQ7TSF6.

Miscellaneous databases

ChiTaRSiMki67. mouse.
NextBioi291926.
SOURCEiSearch...

Gene expression databases

BgeeiQ7TSF6.
GenevisibleiQ7TSF6. MM.

Family and domain databases

InterProiIPR012568. K167R.
[Graphical view]
PfamiPF08065. K167R. 3 hits.
[Graphical view]
SMARTiSM01295. K167R. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: LimbImported.

Entry informationi

Entry nameiQ7TSF6_MOUSE
AccessioniPrimary (citable) accession number: Q7TSF6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: May 11, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.