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Q7TS61

- Q7TS61_RAT

UniProt

Q7TS61 - Q7TS61_RAT

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Protein
Submitted name:

BCL-WS

Gene

Bcl2l2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. BH domain binding Source: RGD
  2. protein heterodimerization activity Source: RGD
  3. protein homodimerization activity Source: RefGenome

GO - Biological processi

  1. apoptotic process Source: RGD
  2. extrinsic apoptotic signaling pathway in absence of ligand Source: RefGenome
  3. intrinsic apoptotic signaling pathway in response to DNA damage Source: RefGenome
  4. negative regulation of apoptotic process Source: RefGenome
  5. negative regulation of intrinsic apoptotic signaling pathway Source: RefGenome
  6. Sertoli cell proliferation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
BCL-WSImported
Gene namesi
Name:Bcl2l2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620717. Bcl2l2.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: RGD
  2. cytosol Source: Ensembl
  3. extracellular vesicular exosome Source: Ensembl
  4. mitochondrial outer membrane Source: RefGenome
  5. mitochondrion Source: RGD
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ7TS61. baseline.
GenevestigatoriQ7TS61.

Structurei

3D structure databases

ProteinModelPortaliQ7TS61.
SMRiQ7TS61. Positions 1-69.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

PhylomeDBiQ7TS61.

Family and domain databases

InterProiIPR013280. Apop_reg_BclW.
IPR002475. Bcl2-like.
IPR020726. Bcl2_BH2_motif_CS.
IPR026298. Blc2_fam.
[Graphical view]
PANTHERiPTHR11256. PTHR11256. 1 hit.
PTHR11256:SF13. PTHR11256:SF13. 1 hit.
PfamiPF00452. Bcl-2. 1 hit.
[Graphical view]
PROSITEiPS50062. BCL2_FAMILY. 1 hit.
PS01258. BH2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TS61-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEPLVGQVQD WMVTYLETRL ADWIHSSGGW AEFTALYGDG ALEEARRLRE
60 70
GNWASVRTVL TGAVALGALV TVGAFFASK
Length:79
Mass (Da):8,602
Last modified:October 1, 2003 - v1
Checksum:i47EDFB3EE2909485
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY185099 mRNA. Translation: AAO64469.1.
UniGeneiRn.44267.

Genome annotation databases

UCSCiRGD:620717. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY185099 mRNA. Translation: AAO64469.1 .
UniGenei Rn.44267.

3D structure databases

ProteinModelPortali Q7TS61.
SMRi Q7TS61. Positions 1-69.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi RGD:620717. rat.

Organism-specific databases

RGDi 620717. Bcl2l2.

Phylogenomic databases

PhylomeDBi Q7TS61.

Gene expression databases

ExpressionAtlasi Q7TS61. baseline.
Genevestigatori Q7TS61.

Family and domain databases

InterProi IPR013280. Apop_reg_BclW.
IPR002475. Bcl2-like.
IPR020726. Bcl2_BH2_motif_CS.
IPR026298. Blc2_fam.
[Graphical view ]
PANTHERi PTHR11256. PTHR11256. 1 hit.
PTHR11256:SF13. PTHR11256:SF13. 1 hit.
Pfami PF00452. Bcl-2. 1 hit.
[Graphical view ]
PROSITEi PS50062. BCL2_FAMILY. 1 hit.
PS01258. BH2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Bcl-2-related protein family gene expression during oligodendroglial differentiation."
    Itoh T., Itoh A., Pleasure D.
    J. Neurochem. 85:1500-1512(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sprague-DawleyImported.

Entry informationi

Entry nameiQ7TS61_RAT
AccessioniPrimary (citable) accession number: Q7TS61
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)