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Q7TS61

- Q7TS61_RAT

UniProt

Q7TS61 - Q7TS61_RAT

Protein
Submitted name:

BCL-WS

Gene

Bcl2l2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. BH domain binding Source: RGD
    2. protein binding Source: RGD
    3. protein heterodimerization activity Source: RGD
    4. protein homodimerization activity Source: RefGenome

    GO - Biological processi

    1. apoptotic process Source: RGD
    2. extrinsic apoptotic signaling pathway in absence of ligand Source: RefGenome
    3. intrinsic apoptotic signaling pathway in response to DNA damage Source: RefGenome
    4. negative regulation of apoptotic process Source: RefGenome
    5. negative regulation of intrinsic apoptotic signaling pathway Source: RefGenome
    6. Sertoli cell proliferation Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    BCL-WSImported
    Gene namesi
    Name:Bcl2l2Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi620717. Bcl2l2.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: RGD
    2. cytosol Source: Ensembl
    3. mitochondrial outer membrane Source: RefGenome
    4. mitochondrion Source: RGD

    Expressioni

    Gene expression databases

    GenevestigatoriQ7TS61.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7TS61.
    SMRiQ7TS61. Positions 1-69.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    PhylomeDBiQ7TS61.

    Family and domain databases

    InterProiIPR013280. Apop_reg_BclW.
    IPR002475. Bcl2-like.
    IPR020726. Bcl2_BH2_motif_CS.
    IPR026298. Blc2_fam.
    [Graphical view]
    PANTHERiPTHR11256. PTHR11256. 1 hit.
    PTHR11256:SF13. PTHR11256:SF13. 1 hit.
    PfamiPF00452. Bcl-2. 1 hit.
    [Graphical view]
    PROSITEiPS50062. BCL2_FAMILY. 1 hit.
    PS01258. BH2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7TS61-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEPLVGQVQD WMVTYLETRL ADWIHSSGGW AEFTALYGDG ALEEARRLRE   50
    GNWASVRTVL TGAVALGALV TVGAFFASK 79
    Length:79
    Mass (Da):8,602
    Last modified:October 1, 2003 - v1
    Checksum:i47EDFB3EE2909485
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY185099 mRNA. Translation: AAO64469.1.
    UniGeneiRn.44267.

    Genome annotation databases

    UCSCiRGD:620717. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY185099 mRNA. Translation: AAO64469.1 .
    UniGenei Rn.44267.

    3D structure databases

    ProteinModelPortali Q7TS61.
    SMRi Q7TS61. Positions 1-69.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi RGD:620717. rat.

    Organism-specific databases

    RGDi 620717. Bcl2l2.

    Phylogenomic databases

    PhylomeDBi Q7TS61.

    Gene expression databases

    Genevestigatori Q7TS61.

    Family and domain databases

    InterProi IPR013280. Apop_reg_BclW.
    IPR002475. Bcl2-like.
    IPR020726. Bcl2_BH2_motif_CS.
    IPR026298. Blc2_fam.
    [Graphical view ]
    PANTHERi PTHR11256. PTHR11256. 1 hit.
    PTHR11256:SF13. PTHR11256:SF13. 1 hit.
    Pfami PF00452. Bcl-2. 1 hit.
    [Graphical view ]
    PROSITEi PS50062. BCL2_FAMILY. 1 hit.
    PS01258. BH2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Bcl-2-related protein family gene expression during oligodendroglial differentiation."
      Itoh T., Itoh A., Pleasure D.
      J. Neurochem. 85:1500-1512(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Sprague-DawleyImported.

    Entry informationi

    Entry nameiQ7TS61_RAT
    AccessioniPrimary (citable) accession number: Q7TS61
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2003
    Last sequence update: October 1, 2003
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)