UniProtKB - Q7TS61 (Q7TS61_RAT)
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Protein
Submitted name:
BCL-WS
Gene
N/A
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- BH domain binding Source: RGD
- disordered domain specific binding Source: RGD
- identical protein binding Source: RGD
- protein heterodimerization activity Source: RGD
GO - Biological processi
- apoptotic process Source: RGD
- extrinsic apoptotic signaling pathway in absence of ligand Source: RGD
- negative regulation of apoptotic process Source: RGD
- Sertoli cell proliferation Source: RGD
Names & Taxonomyi
Protein namesi | Submitted name: BCL-WSImported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 56 – 77 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
MembraneInteractioni
GO - Molecular functioni
- BH domain binding Source: RGD
- disordered domain specific binding Source: RGD
- identical protein binding Source: RGD
- protein heterodimerization activity Source: RGD
Family & Domainsi
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | KOG4209. Eukaryota. ENOG4111PFV. LUCA. |
PhylomeDBi | Q7TS61. |
Family and domain databases
Gene3Di | 1.10.437.10. 1 hit. |
InterProi | View protein in InterPro IPR013280. Apop_reg_BclW. IPR002475. Bcl2-like. IPR020726. Bcl2_BH2_motif_CS. IPR036834. Blc2-like_sf. IPR026298. Blc2_fam. |
PANTHERi | PTHR11256. PTHR11256. 1 hit. PTHR11256:SF13. PTHR11256:SF13. 1 hit. |
SUPFAMi | SSF56854. SSF56854. 1 hit. |
PROSITEi | View protein in PROSITE PS50062. BCL2_FAMILY. 1 hit. PS01258. BH2. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q7TS61-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEPLVGQVQD WMVTYLETRL ADWIHSSGGW AEFTALYGDG ALEEARRLRE
60 70
GNWASVRTVL TGAVALGALV TVGAFFASK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY185099 mRNA. Translation: AAO64469.1. |
UniGenei | Rn.44267. |
Genome annotation databases
UCSCi | RGD:620717. rat. |
Similar proteinsi
Entry informationi
Entry namei | Q7TS61_RAT | |
Accessioni | Q7TS61Primary (citable) accession number: Q7TS61 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2003 |
Last sequence update: | October 1, 2003 | |
Last modified: | February 28, 2018 | |
This is version 79 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |