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Protein

Olfactory receptor

Gene

Olfr735

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. olfactory receptor activity Source: MGI
  3. transmembrane signaling receptor activity Source: GO_Central

GO - Biological processi

  1. detection of chemical stimulus involved in sensory perception Source: GO_Central
  2. detection of chemical stimulus involved in sensory perception of smell Source: GOC
  3. G-protein coupled receptor signaling pathway Source: MGI
  4. sensory perception of smell Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Keywords - Biological processi

OlfactionSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiREACT_252270. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr735Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 14

Organism-specific databases

MGIiMGI:3030569. Olfr735.

Subcellular locationi

Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

GO - Cellular componenti

  1. integral component of membrane Source: MGI
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

GenevestigatoriQ7TRM4.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000056851.

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiNOG146555.
GeneTreeiENSGT00760000119104.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
KOiK04257.
OrthoDBiEOG71K63J.
TreeFamiTF337350.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TRM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHADKQEVL SHNFSFLFNL TYLVQFNFSS TRSLDTLGLE KNKNSSDVSR
60 70 80 90 100
FVLLGLSSSW ELQLFLFFTF LLIYLVIVLG NLLIVMVVQA DAHLFQSPMY
110 120 130 140 150
YFLSHLSFID LCLSCVAVPK MLGDFLQKEK TISFSGCLAQ VFFLHFLGAS
160 170 180 190 200
EMFLLTVMAY DRYVAICNPL HYLTVMNNHL RLRLVFGCWC GGFIHSITQV
210 220 230 240 250
MIVIQLPFCG PNELDNFYCD VPQVVKLACM DTYLVEVLMV SNSGILSLVC
260 270 280 290 300
FLVLLFSYAL ILITLRTHLH RGQSKALSTC ASHLTVVSLI FVPCVFIYLR
310 320 330 340 350
PFCTFSVDKV VSVFYTVITP MLNPLIYTLR NADMKQAIEK LRKKQVASHC

FAKG
Length:354
Mass (Da):40,221
Last modified:July 5, 2004 - v2
Checksum:i8D43C26D39CD0E21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135188 Genomic DNA. No translation available.
AY317860 Genomic DNA. Translation: AAP71198.2.
RefSeqiNP_001011754.1. NM_001011754.2.
UniGeneiMm.482035.

Genome annotation databases

EnsembliENSMUST00000049729; ENSMUSP00000056851; ENSMUSG00000046210.
GeneIDi257909.
KEGGimmu:257909.
UCSCiuc007tky.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135188 Genomic DNA. No translation available.
AY317860 Genomic DNA. Translation: AAP71198.2.
RefSeqiNP_001011754.1. NM_001011754.2.
UniGeneiMm.482035.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000056851.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000049729; ENSMUSP00000056851; ENSMUSG00000046210.
GeneIDi257909.
KEGGimmu:257909.
UCSCiuc007tky.1. mouse.

Organism-specific databases

CTDi257909.
MGIiMGI:3030569. Olfr735.

Phylogenomic databases

eggNOGiNOG146555.
GeneTreeiENSGT00760000119104.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
KOiK04257.
OrthoDBiEOG71K63J.
TreeFamiTF337350.

Enzyme and pathway databases

ReactomeiREACT_252270. Olfactory Signaling Pathway.

Miscellaneous databases

NextBioi387788.
PROiQ7TRM4.
SOURCEiSearch...

Gene expression databases

GenevestigatoriQ7TRM4.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels."
    Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A., Walker M., Williams E.M., Trask B.J.
    Genome Biol. 4:R71.1-R71.13(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Sanders K.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Young J.M.
    Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ7TRM4_MOUSE
AccessioniPrimary (citable) accession number: Q7TRM4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: July 5, 2004
Last modified: March 4, 2015
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.