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Protein

Olfactory receptor

Gene

Olfr745

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Keywords - Biological processi

OlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiR-MMU-381753. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr745Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:3030579. Olfr745.

Subcellular locationi

  • Cell membrane UniRule annotationSAAS annotation; Multi-pass membrane protein UniRule annotationSAAS annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei40 – 6425HelicalUniRule annotationAdd
BLAST
Transmembranei76 – 9419HelicalUniRule annotationAdd
BLAST
Transmembranei114 – 13623HelicalUniRule annotationAdd
BLAST
Transmembranei156 – 17823HelicalUniRule annotationAdd
BLAST
Transmembranei221 – 24222HelicalUniRule annotationAdd
BLAST
Transmembranei254 – 27724HelicalUniRule annotationAdd
BLAST
Transmembranei289 – 30820HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000050184.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini57 – 306250G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IFEZ. Eukaryota.
ENOG411183S. LUCA.
GeneTreeiENSGT00840000129709.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
KOiK04257.
OMAiTMHFVTE.
OrthoDBiEOG7N0C51.
TreeFamiTF338968.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TRL9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITHFSVVSV FLTAFGSKNS SIHFVTEFIL LGFSNQGEMQ SFFFCSILIL
60 70 80 90 100
YLLTLLGNGT IVCAVRWDQR LHTPMYIFLG NFAFLEIWYV SSTIPNMLVN
110 120 130 140 150
ILSENKTISF SACFLQFYFF FSLGTTECFF LSAMAYDRYL AICRPLHYPS
160 170 180 190 200
IMTRKFCVIL ICICWVSGFL CYPVPIVLIS QLPFCGPNII DHFVCDPGPL
210 220 230 240 250
FALSCVPAPS TELLCYTFNS MIIFGPFFCI LGSYTLVLRA VFRVPSGAGR
260 270 280 290 300
TKAFSTCGSH LVVVSLFYGT LMVMYVSPTS GNPAGMQKIV TLIYSALTPL
310 320
LNPLIYTLRN KEMKNALKKL LKLTTIQN
Length:328
Mass (Da):36,823
Last modified:October 1, 2003 - v1
Checksum:iE85740FA9B361D45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140280 Genomic DNA. No translation available.
AY317870 Genomic DNA. Translation: AAP71206.1.
RefSeqiNP_666411.2. NM_146299.2.
UniGeneiMm.377418.

Genome annotation databases

EnsembliENSMUST00000062534; ENSMUSP00000050184; ENSMUSG00000050028.
GeneIDi258296.
KEGGimmu:258296.
UCSCiuc007tlh.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140280 Genomic DNA. No translation available.
AY317870 Genomic DNA. Translation: AAP71206.1.
RefSeqiNP_666411.2. NM_146299.2.
UniGeneiMm.377418.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000050184.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000062534; ENSMUSP00000050184; ENSMUSG00000050028.
GeneIDi258296.
KEGGimmu:258296.
UCSCiuc007tlh.2. mouse.

Organism-specific databases

CTDi258296.
MGIiMGI:3030579. Olfr745.

Phylogenomic databases

eggNOGiENOG410IFEZ. Eukaryota.
ENOG411183S. LUCA.
GeneTreeiENSGT00840000129709.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
KOiK04257.
OMAiTMHFVTE.
OrthoDBiEOG7N0C51.
TreeFamiTF338968.

Enzyme and pathway databases

ReactomeiR-MMU-381753. Olfactory Signaling Pathway.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels."
    Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A., Walker M., Williams E.M., Trask B.J.
    Genome Biol. 4:R71.1-R71.13(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Sanders K.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ7TRL9_MOUSE
AccessioniPrimary (citable) accession number: Q7TRL9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: July 6, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.