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Q7TRL9

- Q7TRL9_MOUSE

UniProt

Q7TRL9 - Q7TRL9_MOUSE

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Protein

Olfactory receptor

Gene

Olfr745

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. olfactory receptor activity Source: MGI

GO - Biological processi

  1. detection of chemical stimulus involved in sensory perception of smell Source: GOC
  2. G-protein coupled receptor signaling pathway Source: MGI
  3. sensory perception of smell Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Keywords - Biological processi

OlfactionSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiREACT_252270. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr745Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 14

Organism-specific databases

MGIiMGI:3030579. Olfr745.

Subcellular locationi

Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

GO - Cellular componenti

  1. integral component of membrane Source: MGI
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

GenevestigatoriQ7TRL9.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000050184.

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiNOG40487.
GeneTreeiENSGT00760000119087.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
KOiK04257.
OMAiNTTMHFV.
OrthoDBiEOG7N0C51.
TreeFamiTF338968.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TRL9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MITHFSVVSV FLTAFGSKNS SIHFVTEFIL LGFSNQGEMQ SFFFCSILIL
60 70 80 90 100
YLLTLLGNGT IVCAVRWDQR LHTPMYIFLG NFAFLEIWYV SSTIPNMLVN
110 120 130 140 150
ILSENKTISF SACFLQFYFF FSLGTTECFF LSAMAYDRYL AICRPLHYPS
160 170 180 190 200
IMTRKFCVIL ICICWVSGFL CYPVPIVLIS QLPFCGPNII DHFVCDPGPL
210 220 230 240 250
FALSCVPAPS TELLCYTFNS MIIFGPFFCI LGSYTLVLRA VFRVPSGAGR
260 270 280 290 300
TKAFSTCGSH LVVVSLFYGT LMVMYVSPTS GNPAGMQKIV TLIYSALTPL
310 320
LNPLIYTLRN KEMKNALKKL LKLTTIQN
Length:328
Mass (Da):36,823
Last modified:October 1, 2003 - v1
Checksum:iE85740FA9B361D45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140280 Genomic DNA. No translation available.
AY317870 Genomic DNA. Translation: AAP71206.1.
RefSeqiNP_666411.2. NM_146299.2.
UniGeneiMm.377418.

Genome annotation databases

EnsembliENSMUST00000062534; ENSMUSP00000050184; ENSMUSG00000050028.
GeneIDi258296.
KEGGimmu:258296.
UCSCiuc007tlh.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140280 Genomic DNA. No translation available.
AY317870 Genomic DNA. Translation: AAP71206.1 .
RefSeqi NP_666411.2. NM_146299.2.
UniGenei Mm.377418.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000050184.

Protein family/group databases

GPCRDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000062534 ; ENSMUSP00000050184 ; ENSMUSG00000050028 .
GeneIDi 258296.
KEGGi mmu:258296.
UCSCi uc007tlh.2. mouse.

Organism-specific databases

CTDi 258296.
MGIi MGI:3030579. Olfr745.

Phylogenomic databases

eggNOGi NOG40487.
GeneTreei ENSGT00760000119087.
HOGENOMi HOG000041362.
HOVERGENi HBG017625.
KOi K04257.
OMAi NTTMHFV.
OrthoDBi EOG7N0C51.
TreeFami TF338968.

Enzyme and pathway databases

Reactomei REACT_252270. Olfactory Signaling Pathway.

Miscellaneous databases

NextBioi 388875.
PROi Q7TRL9.
SOURCEi Search...

Gene expression databases

Genevestigatori Q7TRL9.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels."
    Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A., Walker M., Williams E.M., Trask B.J.
    Genome Biol. 4:R71.1-R71.13(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Sanders K.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ7TRL9_MOUSE
AccessioniPrimary (citable) accession number: Q7TRL9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: November 26, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3