Olfr1045

Functionⁱ

GO - Molecular functionⁱ

G-protein coupled receptor activity Source: UniProtKB-KW
odorant binding Source: GO_Central
olfactory receptor activity
Source: MGI
Inferred from sequence alignmentⁱ
- 14611657

GO - Biological processⁱ

G-protein coupled receptor signaling pathway
Source: MGI
Inferred from sequence alignmentⁱ
- 14611657
sensory perception of smell
Source: MGI
Inferred from sequence alignmentⁱ
- 14611657

Keywordsⁱ

Molecular function	G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological process	OlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

Reactomeⁱ	R-MMU-381753. Olfactory Signaling Pathway.

Reactomeⁱ

R-MMU-381753. Olfactory Signaling Pathway.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Olfactory receptorUniRule annotation
Gene namesⁱ	Name:Olfr1045Imported ORF Names:mCG_142534Imported
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 2

Organism-specific databases

MGIⁱ	MGI:3030879. Olfr1045.

Subcellular locationⁱ

Cell membrane
UniRule annotation
Automatic assertion according to rulesⁱ
- RuleBase:RU363047
SAAS annotation
Automatic assertion according to rulesⁱ
- SAAS:SAAS00857205
; Multi-pass membrane protein
UniRule annotation
Automatic assertion according to rulesⁱ
- RuleBase:RU363047
SAAS annotation
Automatic assertion according to rulesⁱ
- SAAS:SAAS00857205

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	27 – 49	HelicalUniRule annotationAdd BLAST	23
Transmembraneⁱ	61 – 81	HelicalUniRule annotationAdd BLAST	21
Transmembraneⁱ	101 – 120	HelicalUniRule annotationAdd BLAST	20
Transmembraneⁱ	141 – 168	HelicalUniRule annotationAdd BLAST	28
Transmembraneⁱ	200 – 226	HelicalUniRule annotationAdd BLAST	27
Transmembraneⁱ	238 – 261	HelicalUniRule annotationAdd BLAST	24
Transmembraneⁱ	273 – 292	HelicalUniRule annotationAdd BLAST	20

GO - Cellular componentⁱ

integral component of membrane
Source: MGI
Inferred from sequence alignmentⁱ
- 14611657
plasma membrane Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

Cell membraneUniRule annotationSAAS annotation, Membrane

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000075198.

Bgeeⁱ

ENSMUSG00000075198.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000097488.

STRINGⁱ

10090.ENSMUSP00000097488.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	41 – 290	G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST		250

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	ENOG410IF11. Eukaryota. ENOG411183X. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00810000125371.
HOGENOMⁱ	HOG000041364.
HOVERGENⁱ	HBG017625.
KEGG Orthology (KO) More...KOⁱ	K04257.
OMAⁱ	KFMENPC.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0AZH.
TreeFamⁱ	TF352753.

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR000725. Olfact_rcpt.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13853. 7tm_4. 1 hit.
PRINTSⁱ	PR00237. GPCRRHODOPSN. PR00245. OLFACTORYR.
PROSITEⁱ	View protein in PROSITE PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q7TR80-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAPRNLSHVT EFILVGVSDL PELQVPLFFV FLVIYLLTAA GNLGIITLTS 
        60         70         80         90        100
VDSRLQTPMY FFLRHLAVIN FGNSTVIAPK MLVNFLVSKK TTLYYECATQ 
       110        120        130        140        150
LGGFLVFIVA EIFMLAVMAY DRYVAICNPL LYMVVVSRRV CLLLVSLTYF 
       160        170        180        190        200
YGFCTAIVVS SCVFSVSYCS SKKINHFYCD NVPLLALSCS DTYLPETVVF 
       210        220        230        240        250
ISAATNLFFS MSIVLVSYFN IVLSILRIRS AEGRKKAFST CASHVMAVTV 
       260        270        280        290        300
FYGTLLFMYL QPQTNHSLDT DKMASVFYTL VIPMLNPMIY SLRNKDVKAA 
       310 
LKRFMTSPCD SFKSL

Length:315

Mass (Da):35,350

Last modified:October 1, 2003 - v1

Checksum:ⁱ9E213314C7B41DFE

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL845499 Genomic DNA. No translation available. AY318241 Genomic DNA. Translation: AAP71491.1. CH466519 Genomic DNA. Translation: EDL27356.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_667228.2. NM_147017.2.
UniGeneⁱ	Mm.377791.

Genome annotation databases

Ensemblⁱ	ENSMUST00000099904; ENSMUSP00000097488; ENSMUSG00000075198. ENSMUST00000215763; ENSMUSP00000148982; ENSMUSG00000075198.
GeneIDⁱ	259019.
KEGGⁱ	mmu:259019.
UCSC genome browser More...UCSCⁱ	uc008klv.1. mouse.

Similar proteinsⁱ

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
Q7TR80	UPI00077DCB08 D3ZA98 Q8VGS5 UPI00022F530E UPI00033304CF UPI00038C5A1E UPI00042AEEF2 UPI000A305B43 UPI000A315261 UPI000B4EC197 +1	Mus musculus (Mouse) Peromyscus maniculatus bairdii (prairie deer mouse) Rattus norvegicus (Rat) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) Jaculus jaculus (Lesser Egyptian jerboa) Microtus ochrogaster (Prairie vole) Mus pahari (Gairdner's shrew-mouse) (Coelomys pahari) Mus caroli (Ryukyu mouse) (Ricefield mouse) Meriones unguiculatus (Mongolian jird) (Mongolian gerbil) Mesocricetus auratus (Golden hamster)	315	UniRef90_Q7TR80	Cluster: Olfactory receptor	12

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
Q7TR80	Q8WZ84 A0A126GVG6 UPI0005F3963C UPI0000E5088B UPI00083C84C4 UPI00053352CB G3QIY5 UPI000274524B H2NFP5 UPI0005F48A7B +2159	Homo sapiens (Human) Colobus angolensis palliatus (Peters' Angolan colobus) Pan troglodytes (Chimpanzee) Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Gorilla gorilla gorilla (Western lowland gorilla) Pan paniscus (Pygmy chimpanzee) (Bonobo) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Macaca nemestrina (Pig-tailed macaque) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) And more	308	UniRef50_Q8WZ84	Cluster: Olfactory receptor 8D1	2,170

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL845499 Genomic DNA. No translation available. AY318241 Genomic DNA. Translation: AAP71491.1. CH466519 Genomic DNA. Translation: EDL27356.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_667228.2. NM_147017.2.
UniGeneⁱ	Mm.377791.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000097488.

STRINGⁱ

10090.ENSMUSP00000097488.

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	259019.
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000099904; ENSMUSP00000097488; ENSMUSG00000075198. ENSMUST00000215763; ENSMUSP00000148982; ENSMUSG00000075198.
GeneIDⁱ	259019.
KEGGⁱ	mmu:259019.
UCSC genome browser More...UCSCⁱ	uc008klv.1. mouse.

Organism-specific databases

CTDⁱ	259019.
MGIⁱ	MGI:3030879. Olfr1045.

Phylogenomic databases

eggNOGⁱ	ENOG410IF11. Eukaryota. ENOG411183X. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00810000125371.
HOGENOMⁱ	HOG000041364.
HOVERGENⁱ	HBG017625.
KEGG Orthology (KO) More...KOⁱ	K04257.
OMAⁱ	KFMENPC.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0AZH.
TreeFamⁱ	TF352753.

Enzyme and pathway databases

Reactomeⁱ	R-MMU-381753. Olfactory Signaling Pathway.

Reactomeⁱ

R-MMU-381753. Olfactory Signaling Pathway.

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000075198.

Bgeeⁱ

ENSMUSG00000075198.

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR000725. Olfact_rcpt.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13853. 7tm_4. 1 hit.
PRINTSⁱ	PR00237. GPCRRHODOPSN. PR00245. OLFACTORYR.
PROSITEⁱ	View protein in PROSITE PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q7TR80_MOUSE
Accessionⁱ	Q7TR80Primary (citable) accession number: Q7TR80
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 1, 2003
	Last sequence update:	October 1, 2003
	Last modified:	August 30, 2017
	This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q7TR80 (Q7TR80_MOUSE)

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Olfactory receptor

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ