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Protein

Probable G-protein coupled receptor 141

Gene

Gpr141

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Orphan receptor.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Probable G-protein coupled receptor 141
Alternative name(s):
G-protein coupled receptor PGR13
Gene namesi
Name:Gpr141
Synonyms:Pgr13
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:2672983. Gpr141.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 22ExtracellularSequence analysisAdd BLAST22
Transmembranei23 – 43Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini44 – 50CytoplasmicSequence analysis7
Transmembranei51 – 71Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini72 – 91ExtracellularSequence analysisAdd BLAST20
Transmembranei92 – 112Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini113 – 131CytoplasmicSequence analysisAdd BLAST19
Transmembranei132 – 152Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini153 – 184ExtracellularSequence analysisAdd BLAST32
Transmembranei185 – 205Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini206 – 227CytoplasmicSequence analysisAdd BLAST22
Transmembranei228 – 248Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini249 – 267ExtracellularSequence analysisAdd BLAST19
Transmembranei268 – 288Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini289 – 305CytoplasmicSequence analysisAdd BLAST17

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000696191 – 305Probable G-protein coupled receptor 141Add BLAST305

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi5N-linked (GlcNAc...)Sequence analysis1
Glycosylationi9N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ7TQP0.
PRIDEiQ7TQP0.

PTM databases

PhosphoSitePlusiQ7TQP0.

Expressioni

Gene expression databases

BgeeiENSMUSG00000053101.
CleanExiMM_GPR141.

Structurei

3D structure databases

ProteinModelPortaliQ7TQP0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IN12. Eukaryota.
ENOG410Y9TY. LUCA.
GeneTreeiENSGT00730000111106.
HOGENOMiHOG000090258.
HOVERGENiHBG051782.
InParanoidiQ7TQP0.
KOiK08429.
OMAiHQEFWAQ.
OrthoDBiEOG091G0UEI.
PhylomeDBiQ7TQP0.
TreeFamiTF333221.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TQP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGYNTSENS SCDPILAHHL TSIYFIVLIG GLVGLISILF LLVKMNSRSV
60 70 80 90 100
TTMAVINLVV VHGVFLLTVP FRLAYLIKGT WTFGLPFCKF VSAMLHIHMY
110 120 130 140 150
LTFLFYVVIL VIRYLIFFKR RDKVEFYRKL HAVAASSAMW LLVIVIVVPL
160 170 180 190 200
VVSQYGNSEE YNEQQCFRFH KELGHDSVRV INYMIVIVVI AVALILLGFQ
210 220 230 240 250
VFITLSMVRK FRHSLLSHQE FWAQLKNLFF IGIIIICFLP YQFFRIYYLY
260 270 280 290 300
VVAHSKSCKN KVAFYNEILL STTAISCCDL LLFVFGGSHW VKQKIVDMWN

CLLCH
Length:305
Mass (Da):35,284
Last modified:October 1, 2003 - v1
Checksum:i74C7EB210158D554
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY288427 mRNA. Translation: AAP72136.1.
BC125585 mRNA. Translation: AAI25586.1.
BC125587 mRNA. Translation: AAI25588.1.
AY255553 mRNA. Translation: AAO85065.1.
CCDSiCCDS26264.1.
RefSeqiNP_861419.3. NM_181754.4.
XP_006516766.1. XM_006516703.3.
XP_006516767.1. XM_006516704.3.
XP_006516768.1. XM_006516705.3.
XP_011242615.1. XM_011244313.2.
XP_011242616.1. XM_011244314.2.
XP_011242617.1. XM_011244315.2.
XP_011242618.1. XM_011244316.2.
UniGeneiMm.239268.

Genome annotation databases

EnsembliENSMUST00000065335; ENSMUSP00000066921; ENSMUSG00000053101.
GeneIDi353346.
KEGGimmu:353346.
UCSCiuc007ppl.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY288427 mRNA. Translation: AAP72136.1.
BC125585 mRNA. Translation: AAI25586.1.
BC125587 mRNA. Translation: AAI25588.1.
AY255553 mRNA. Translation: AAO85065.1.
CCDSiCCDS26264.1.
RefSeqiNP_861419.3. NM_181754.4.
XP_006516766.1. XM_006516703.3.
XP_006516767.1. XM_006516704.3.
XP_006516768.1. XM_006516705.3.
XP_011242615.1. XM_011244313.2.
XP_011242616.1. XM_011244314.2.
XP_011242617.1. XM_011244315.2.
XP_011242618.1. XM_011244316.2.
UniGeneiMm.239268.

3D structure databases

ProteinModelPortaliQ7TQP0.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

PTM databases

PhosphoSitePlusiQ7TQP0.

Proteomic databases

PaxDbiQ7TQP0.
PRIDEiQ7TQP0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000065335; ENSMUSP00000066921; ENSMUSG00000053101.
GeneIDi353346.
KEGGimmu:353346.
UCSCiuc007ppl.1. mouse.

Organism-specific databases

CTDi353345.
MGIiMGI:2672983. Gpr141.

Phylogenomic databases

eggNOGiENOG410IN12. Eukaryota.
ENOG410Y9TY. LUCA.
GeneTreeiENSGT00730000111106.
HOGENOMiHOG000090258.
HOVERGENiHBG051782.
InParanoidiQ7TQP0.
KOiK08429.
OMAiHQEFWAQ.
OrthoDBiEOG091G0UEI.
PhylomeDBiQ7TQP0.
TreeFamiTF333221.

Miscellaneous databases

PROiQ7TQP0.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000053101.
CleanExiMM_GPR141.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGP141_MOUSE
AccessioniPrimary (citable) accession number: Q7TQP0
Secondary accession number(s): Q059N8, Q80UC5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: October 1, 2003
Last modified: November 2, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.