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Q7TQP0

- GP141_MOUSE

UniProt

Q7TQP0 - GP141_MOUSE

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Protein

Probable G-protein coupled receptor 141

Gene
Gpr141, Pgr13
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Orphan receptor.

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Probable G-protein coupled receptor 141
Alternative name(s):
G-protein coupled receptor PGR13
Gene namesi
Name:Gpr141
Synonyms:Pgr13
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13

Organism-specific databases

MGIiMGI:2672983. Gpr141.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2222Extracellular Reviewed predictionAdd
BLAST
Transmembranei23 – 4321Helical; Name=1; Reviewed predictionAdd
BLAST
Topological domaini44 – 507Cytoplasmic Reviewed prediction
Transmembranei51 – 7121Helical; Name=2; Reviewed predictionAdd
BLAST
Topological domaini72 – 9120Extracellular Reviewed predictionAdd
BLAST
Transmembranei92 – 11221Helical; Name=3; Reviewed predictionAdd
BLAST
Topological domaini113 – 13119Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei132 – 15221Helical; Name=4; Reviewed predictionAdd
BLAST
Topological domaini153 – 18432Extracellular Reviewed predictionAdd
BLAST
Transmembranei185 – 20521Helical; Name=5; Reviewed predictionAdd
BLAST
Topological domaini206 – 22722Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei228 – 24821Helical; Name=6; Reviewed predictionAdd
BLAST
Topological domaini249 – 26719Extracellular Reviewed predictionAdd
BLAST
Transmembranei268 – 28821Helical; Name=7; Reviewed predictionAdd
BLAST
Topological domaini289 – 30517Cytoplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 305305Probable G-protein coupled receptor 141PRO_0000069619Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi5 – 51N-linked (GlcNAc...) Reviewed prediction
Glycosylationi9 – 91N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ7TQP0.

PTM databases

PhosphoSiteiQ7TQP0.

Expressioni

Gene expression databases

BgeeiQ7TQP0.
CleanExiMM_GPR141.
GenevestigatoriQ7TQP0.

Structurei

3D structure databases

ProteinModelPortaliQ7TQP0.
SMRiQ7TQP0. Positions 22-154.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG139824.
GeneTreeiENSGT00730000111106.
HOGENOMiHOG000090258.
HOVERGENiHBG051782.
InParanoidiQ059N8.
KOiK08429.
OMAiHQEFWAQ.
OrthoDBiEOG7CNZGZ.
PhylomeDBiQ7TQP0.
TreeFamiTF333221.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TQP0-1 [UniParc]FASTAAdd to Basket

« Hide

MDGYNTSENS SCDPILAHHL TSIYFIVLIG GLVGLISILF LLVKMNSRSV    50
TTMAVINLVV VHGVFLLTVP FRLAYLIKGT WTFGLPFCKF VSAMLHIHMY 100
LTFLFYVVIL VIRYLIFFKR RDKVEFYRKL HAVAASSAMW LLVIVIVVPL 150
VVSQYGNSEE YNEQQCFRFH KELGHDSVRV INYMIVIVVI AVALILLGFQ 200
VFITLSMVRK FRHSLLSHQE FWAQLKNLFF IGIIIICFLP YQFFRIYYLY 250
VVAHSKSCKN KVAFYNEILL STTAISCCDL LLFVFGGSHW VKQKIVDMWN 300
CLLCH 305
Length:305
Mass (Da):35,284
Last modified:October 1, 2003 - v1
Checksum:i74C7EB210158D554
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY288427 mRNA. Translation: AAP72136.1.
BC125585 mRNA. Translation: AAI25586.1.
BC125587 mRNA. Translation: AAI25588.1.
AY255553 mRNA. Translation: AAO85065.1.
CCDSiCCDS26264.1.
RefSeqiNP_861419.3. NM_181754.4.
XP_006516766.1. XM_006516703.1.
XP_006516767.1. XM_006516704.1.
XP_006516768.1. XM_006516705.1.
XP_006516769.1. XM_006516706.1.
UniGeneiMm.239268.

Genome annotation databases

EnsembliENSMUST00000065335; ENSMUSP00000066921; ENSMUSG00000053101.
GeneIDi353346.
KEGGimmu:353346.
UCSCiuc007ppl.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY288427 mRNA. Translation: AAP72136.1 .
BC125585 mRNA. Translation: AAI25586.1 .
BC125587 mRNA. Translation: AAI25588.1 .
AY255553 mRNA. Translation: AAO85065.1 .
CCDSi CCDS26264.1.
RefSeqi NP_861419.3. NM_181754.4.
XP_006516766.1. XM_006516703.1.
XP_006516767.1. XM_006516704.1.
XP_006516768.1. XM_006516705.1.
XP_006516769.1. XM_006516706.1.
UniGenei Mm.239268.

3D structure databases

ProteinModelPortali Q7TQP0.
SMRi Q7TQP0. Positions 22-154.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

GPCRDBi Search...

PTM databases

PhosphoSitei Q7TQP0.

Proteomic databases

PRIDEi Q7TQP0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000065335 ; ENSMUSP00000066921 ; ENSMUSG00000053101 .
GeneIDi 353346.
KEGGi mmu:353346.
UCSCi uc007ppl.1. mouse.

Organism-specific databases

CTDi 353345.
MGIi MGI:2672983. Gpr141.

Phylogenomic databases

eggNOGi NOG139824.
GeneTreei ENSGT00730000111106.
HOGENOMi HOG000090258.
HOVERGENi HBG051782.
InParanoidi Q059N8.
KOi K08429.
OMAi HQEFWAQ.
OrthoDBi EOG7CNZGZ.
PhylomeDBi Q7TQP0.
TreeFami TF333221.

Miscellaneous databases

NextBioi 400421.
PROi Q7TQP0.
SOURCEi Search...

Gene expression databases

Bgeei Q7TQP0.
CleanExi MM_GPR141.
Genevestigatori Q7TQP0.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view ]
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PROSITEi PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives."
    Fredriksson R., Hoeglund P.J., Gloriam D.E.I., Lagerstroem M.C., Schioeth H.B.
    FEBS Lett. 554:381-388(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 174-304.

Entry informationi

Entry nameiGP141_MOUSE
AccessioniPrimary (citable) accession number: Q7TQP0
Secondary accession number(s): Q059N8, Q80UC5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: October 1, 2003
Last modified: July 9, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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