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Q7TQP0 (GP141_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable G-protein coupled receptor 141
Alternative name(s):
G-protein coupled receptor PGR13
Gene names
Name:Gpr141
Synonyms:Pgr13
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Orphan receptor.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 305305Probable G-protein coupled receptor 141
PRO_0000069619

Regions

Topological domain1 – 2222Extracellular Potential
Transmembrane23 – 4321Helical; Name=1; Potential
Topological domain44 – 507Cytoplasmic Potential
Transmembrane51 – 7121Helical; Name=2; Potential
Topological domain72 – 9120Extracellular Potential
Transmembrane92 – 11221Helical; Name=3; Potential
Topological domain113 – 13119Cytoplasmic Potential
Transmembrane132 – 15221Helical; Name=4; Potential
Topological domain153 – 18432Extracellular Potential
Transmembrane185 – 20521Helical; Name=5; Potential
Topological domain206 – 22722Cytoplasmic Potential
Transmembrane228 – 24821Helical; Name=6; Potential
Topological domain249 – 26719Extracellular Potential
Transmembrane268 – 28821Helical; Name=7; Potential
Topological domain289 – 30517Cytoplasmic Potential

Amino acid modifications

Glycosylation51N-linked (GlcNAc...) Potential
Glycosylation91N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q7TQP0 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 74C7EB210158D554

FASTA30535,284
        10         20         30         40         50         60 
MDGYNTSENS SCDPILAHHL TSIYFIVLIG GLVGLISILF LLVKMNSRSV TTMAVINLVV 

        70         80         90        100        110        120 
VHGVFLLTVP FRLAYLIKGT WTFGLPFCKF VSAMLHIHMY LTFLFYVVIL VIRYLIFFKR 

       130        140        150        160        170        180 
RDKVEFYRKL HAVAASSAMW LLVIVIVVPL VVSQYGNSEE YNEQQCFRFH KELGHDSVRV 

       190        200        210        220        230        240 
INYMIVIVVI AVALILLGFQ VFITLSMVRK FRHSLLSHQE FWAQLKNLFF IGIIIICFLP 

       250        260        270        280        290        300 
YQFFRIYYLY VVAHSKSCKN KVAFYNEILL STTAISCCDL LLFVFGGSHW VKQKIVDMWN 


CLLCH 

« Hide

References

« Hide 'large scale' references
[1]"Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives."
Fredriksson R., Hoeglund P.J., Gloriam D.E.I., Lagerstroem M.C., Schioeth H.B.
FEBS Lett. 554:381-388(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.
[3]"The G protein-coupled receptor repertoires of human and mouse."
Vassilatis D.K., Hohmann J.G., Zeng H., Li F., Ranchalis J.E., Mortrud M.T., Brown A., Rodriguez S.S., Weller J.R., Wright A.C., Bergmann J.E., Gaitanaris G.A.
Proc. Natl. Acad. Sci. U.S.A. 100:4903-4908(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 174-304.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY288427 mRNA. Translation: AAP72136.1.
BC125585 mRNA. Translation: AAI25586.1.
BC125587 mRNA. Translation: AAI25588.1.
AY255553 mRNA. Translation: AAO85065.1.
CCDSCCDS26264.1.
RefSeqNP_861419.3. NM_181754.4.
XP_006516766.1. XM_006516703.1.
XP_006516767.1. XM_006516704.1.
XP_006516768.1. XM_006516705.1.
XP_006516769.1. XM_006516706.1.
UniGeneMm.239268.

3D structure databases

ProteinModelPortalQ7TQP0.
SMRQ7TQP0. Positions 22-154.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

GPCRDBSearch...

PTM databases

PhosphoSiteQ7TQP0.

Proteomic databases

PRIDEQ7TQP0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000065335; ENSMUSP00000066921; ENSMUSG00000053101.
GeneID353346.
KEGGmmu:353346.
UCSCuc007ppl.1. mouse.

Organism-specific databases

CTD353345.
MGIMGI:2672983. Gpr141.

Phylogenomic databases

eggNOGNOG139824.
GeneTreeENSGT00730000111106.
HOGENOMHOG000090258.
HOVERGENHBG051782.
InParanoidQ059N8.
KOK08429.
OMAHQEFWAQ.
OrthoDBEOG7CNZGZ.
PhylomeDBQ7TQP0.
TreeFamTF333221.

Gene expression databases

BgeeQ7TQP0.
CleanExMM_GPR141.
GenevestigatorQ7TQP0.

Family and domain databases

Gene3D1.20.1070.10. 1 hit.
InterProIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSPR00237. GPCRRHODOPSN.
PROSITEPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio400421.
PROQ7TQP0.
SOURCESearch...

Entry information

Entry nameGP141_MOUSE
AccessionPrimary (citable) accession number: Q7TQP0
Secondary accession number(s): Q059N8, Q80UC5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: October 1, 2003
Last modified: July 9, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

7-transmembrane G-linked receptors

List of 7-transmembrane G-linked receptor entries