Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable G-protein coupled receptor 142

Gene

Gpr142

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Orphan receptor.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Probable G-protein coupled receptor 142
Gene namesi
Name:Gpr142
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:2668437. Gpr142.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 6666ExtracellularSequence analysisAdd
BLAST
Transmembranei67 – 8721Helical; Name=1Sequence analysisAdd
BLAST
Topological domaini88 – 10215CytoplasmicSequence analysisAdd
BLAST
Transmembranei103 – 12321Helical; Name=2Sequence analysisAdd
BLAST
Topological domaini124 – 14017ExtracellularSequence analysisAdd
BLAST
Transmembranei141 – 16121Helical; Name=3Sequence analysisAdd
BLAST
Topological domaini162 – 18524CytoplasmicSequence analysisAdd
BLAST
Transmembranei186 – 20621Helical; Name=4Sequence analysisAdd
BLAST
Topological domaini207 – 22418ExtracellularSequence analysisAdd
BLAST
Transmembranei225 – 24521Helical; Name=5Sequence analysisAdd
BLAST
Topological domaini246 – 26419CytoplasmicSequence analysisAdd
BLAST
Transmembranei265 – 28521Helical; Name=6Sequence analysisAdd
BLAST
Topological domaini286 – 30419ExtracellularSequence analysisAdd
BLAST
Transmembranei305 – 32521Helical; Name=7Sequence analysisAdd
BLAST
Topological domaini326 – 36540CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • cell junction Source: MGI
  • cytoplasm Source: MGI
  • integral component of membrane Source: MGI
  • plasma membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Chemistry

ChEMBLiCHEMBL2069162.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 365365Probable G-protein coupled receptor 142PRO_0000069621Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi44 – 441N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ7TQN9.
PRIDEiQ7TQN9.

PTM databases

PhosphoSiteiQ7TQN9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000034677.
CleanExiMM_GPR142.
ExpressionAtlasiQ7TQN9. differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000045029.

Chemistry

BindingDBiQ7TQN9.

Structurei

3D structure databases

ProteinModelPortaliQ7TQN9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00390000006613.
HOGENOMiHOG000231257.
HOVERGENiHBG051783.
InParanoidiQ7TQN9.
KOiK08430.
PhylomeDBiQ7TQN9.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TQN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHLNSNPNSY ICDAYQHADL LWSLSPHVLT KAVQPQVTLL PTVNGSNPRY
60 70 80 90 100
DGVDGHWPES PERSPCVAGI IPVIYYSVLL SLGLPVALAR LAARTRKPSY
110 120 130 140 150
HYLLALTASD IVTQVIIVFV GFLLQGAVLA RQVPQAVVRT ANILEFAANH
160 170 180 190 200
ASVWIAVLFT VDRYNALCRP LRHRATSSPG RTHRAIAAVI GVTLLTGIPF
210 220 230 240 250
YWWLDVWRDA DPPSTMDKLL KWAHCLIVYF IPCNVFLVTN SAIILRLRKR
260 270 280 290 300
GQRGLRPLVS KSTAILLGVT SLFALLWAPR IIVMLYHLYV APVHRDWRVH
310 320 330 340 350
LALDIANMLA MLNTEVNFGL YCFISKTFRA TVRQVICDVH MACALKSQPK
360
QTVVELMLKS VGTEL
Length:365
Mass (Da):40,758
Last modified:October 1, 2003 - v1
Checksum:iACA8649245CDAE47
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY288428 mRNA. Translation: AAP72137.1.
CCDSiCCDS25611.1.
RefSeqiNP_861414.1. NM_181749.1.
UniGeneiMm.269127.

Genome annotation databases

EnsembliENSMUST00000045319; ENSMUSP00000045029; ENSMUSG00000034677.
GeneIDi217302.
KEGGimmu:217302.
UCSCiuc007mfu.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY288428 mRNA. Translation: AAP72137.1.
CCDSiCCDS25611.1.
RefSeqiNP_861414.1. NM_181749.1.
UniGeneiMm.269127.

3D structure databases

ProteinModelPortaliQ7TQN9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000045029.

Chemistry

BindingDBiQ7TQN9.
ChEMBLiCHEMBL2069162.

Protein family/group databases

GPCRDBiSearch...

PTM databases

PhosphoSiteiQ7TQN9.

Proteomic databases

PaxDbiQ7TQN9.
PRIDEiQ7TQN9.

Protocols and materials databases

DNASUi217302.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000045319; ENSMUSP00000045029; ENSMUSG00000034677.
GeneIDi217302.
KEGGimmu:217302.
UCSCiuc007mfu.1. mouse.

Organism-specific databases

CTDi350383.
MGIiMGI:2668437. Gpr142.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00390000006613.
HOGENOMiHOG000231257.
HOVERGENiHBG051783.
InParanoidiQ7TQN9.
KOiK08430.
PhylomeDBiQ7TQN9.

Miscellaneous databases

PROiQ7TQN9.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000034677.
CleanExiMM_GPR142.
ExpressionAtlasiQ7TQN9. differential.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGP142_MOUSE
AccessioniPrimary (citable) accession number: Q7TQN9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: October 1, 2003
Last modified: September 7, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.