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Protein

Ankyrin repeat and BTB/POZ domain-containing protein 2

Gene

Abtb2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May be involved in the initiation of hepatocyte growth.By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Ankyrin repeat and BTB/POZ domain-containing protein 2
Gene namesi
Name:Abtb2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:2139365 Abtb2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000668881 – 1024Ankyrin repeat and BTB/POZ domain-containing protein 2Add BLAST1024

Proteomic databases

EPDiQ7TQI7
MaxQBiQ7TQI7
PaxDbiQ7TQI7
PRIDEiQ7TQI7

PTM databases

iPTMnetiQ7TQI7
PhosphoSitePlusiQ7TQI7

Expressioni

Gene expression databases

BgeeiENSMUSG00000032724
CleanExiMM_ABTB2
ExpressionAtlasiQ7TQI7 baseline and differential
GenevisibleiQ7TQI7 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000075566

Structurei

3D structure databases

ProteinModelPortaliQ7TQI7
SMRiQ7TQI7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati521 – 550ANK 1Add BLAST30
Repeati567 – 596ANK 2Add BLAST30
Repeati606 – 635ANK 3Add BLAST30
Repeati649 – 678ANK 4Add BLAST30
Domaini844 – 913BTBPROSITE-ProRule annotationAdd BLAST70

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiENOG410IESM Eukaryota
ENOG410XRDX LUCA
GeneTreeiENSGT00550000074669
HOGENOMiHOG000033776
HOVERGENiHBG050447
InParanoidiQ7TQI7
KOiK10521
OMAiTYKYAKI
OrthoDBiEOG091G010V
PhylomeDBiQ7TQI7
TreeFamiTF106437

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.10.20.10, 1 hit
1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR000210 BTB/POZ_dom
IPR009072 Histone-fold
IPR011333 SKP1/BTB/POZ_sf
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF00651 BTB, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 5 hits
SM00225 BTB, 1 hit
SUPFAMiSSF47113 SSF47113, 2 hits
SSF48403 SSF48403, 1 hit
SSF54695 SSF54695, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 3 hits
PS50097 BTB, 1 hit

Sequencei

Sequence statusi: Complete.

Q7TQI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGTYSSTLK TLEDLTLDSG YGAGDSCRSL SLSSSKSNSQ ALNSSAQQHR
60 70 80 90 100
GAAWWCYSGS MNSRHNSWDT VNTVLPEDPE VADLFSRCPR LPELEEFPWT
110 120 130 140 150
EGDVARVLRK SVGGRRLPSF SAEAVRRLAG LLRRALIRVA REAQRLSVLH
160 170 180 190 200
AKCTRFEVQS AVRLVHSWAL AESCALAAVK ALSLYSMSAG DGLRRGKSAR
210 220 230 240 250
CGLTFSVGRF FRWMVDTRIS VRIHEYAAIS LTACMENLVE EIRARVLASQ
260 270 280 290 300
SPDGGGAGGG EVSAEALEMV INNDAELWGV LQPYEHLICG KNANGVLSLP
310 320 330 340 350
AYFSPYNGGS LGHDERADAY AQLELRTLEQ SLLATCVGSI SELSDLVSRA
360 370 380 390 400
MHHMQGRHPL CPGTSPARQA RQPPQPITWS PDALHTLYYF LRCPQMESME
410 420 430 440 450
NPNLDPPRMT LNNERPFMLL PPLMEWMRVA ITYAEHRRSP TVDSGDIRQA
460 470 480 490 500
ARLLLPGLDC EPRQLKPECC FSSFRRLDAR AATERFNQDL GFRMLNCGRT
510 520 530 540 550
DLISQAIEAL GPDGVNTMDD QGMTPLMYAC AAGDEAMVQM LIDAGANLDI
560 570 580 590 600
QVPSHSPRHP SVHPDSRHWT SLTFAVLHGH ISVVQLLLDA GAHVEGSAVN
610 620 630 640 650
SGEDSYAETP LQLASAAGNY ELVSLLLSRG ADPLLSMLEA NGMASSLHEE
660 670 680 690 700
MNCFSHSAAH GHRNVLRKLL TQPQQAKADV LSLEEILAEG VEESDTSSQG
710 720 730 740 750
SSEGPVRLSR TRTKALQEAM YYSAEHGYLD ITMELRALGV PWKLHIWIES
760 770 780 790 800
LRTSFSQSRY SVVQSLLKDF SSIKEEEYNE ELVTEGLQLM FDILKTSKND
810 820 830 840 850
SVLQQLATIF THCYGTSPIP SIPEIRKTLP ARLDPHFLNN KEMSDVTFLV
860 870 880 890 900
EGKLFYAHKV LLVTASNRFK TLMTNKSEQD GDSSKTIEIS DIKYHIFQML
910 920 930 940 950
MQYLYYGGTE SMEIPTADIL QLLSAANLFQ LDALQRHCEI LCSQTLSVES
960 970 980 990 1000
AVNTYKYAKI HNAPELALFC EGFFLKHMKA LLEQDAFRQL IYGRSSKVQG
1010 1020
LDPLQDLQST LAERVHSVYV TSRV
Length:1,024
Mass (Da):113,503
Last modified:October 1, 2003 - v1
Checksum:i39509A02F0DE093A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC054399 mRNA Translation: AAH54399.1
CCDSiCCDS16479.1
RefSeqiNP_849221.2, NM_178890.3
UniGeneiMm.35850

Genome annotation databases

EnsembliENSMUST00000076212; ENSMUSP00000075566; ENSMUSG00000032724
GeneIDi99382
KEGGimmu:99382
UCSCiuc008lix.1 mouse

Similar proteinsi

Entry informationi

Entry nameiABTB2_MOUSE
AccessioniPrimary (citable) accession number: Q7TQI7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: October 1, 2003
Last modified: April 25, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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