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Protein
Submitted name:

Aa1018

Gene

Vtn

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • collagen binding Source: RGD
  • extracellular matrix binding Source: RGD
  • heparin binding Source: RGD
  • identical protein binding Source: RGD
  • integrin binding Source: RGD
  • polysaccharide binding Source: InterPro
  • scavenger receptor activity Source: InterPro

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-2129379. Molecules associated with elastic fibres.
R-RNO-216083. Integrin cell surface interactions.
R-RNO-3000170. Syndecan interactions.
R-RNO-3000178. ECM proteoglycans.
R-RNO-977606. Regulation of Complement cascade.

Names & Taxonomyi

Protein namesi
Submitted name:
Aa1018Imported
Submitted name:
VitronectinImported
Gene namesi
Name:VtnImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi3967. Vtn.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_501121092120 – 490Sequence analysisAdd BLAST471

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000010031.

Interactioni

GO - Molecular functioni

  • collagen binding Source: RGD
  • identical protein binding Source: RGD
  • integrin binding Source: RGD

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 63SMBInterPro annotationAdd BLAST44
Repeati156 – 209HemopexinPROSITE-ProRule annotationAdd BLAST54
Repeati210 – 257HemopexinPROSITE-ProRule annotationAdd BLAST48
Repeati258 – 315HemopexinPROSITE-ProRule annotationAdd BLAST58
Repeati428 – 485HemopexinPROSITE-ProRule annotationAdd BLAST58

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1565. Eukaryota.
ENOG410XQ5D. LUCA.
GeneTreeiENSGT00530000063751.
HOGENOMiHOG000133161.
HOVERGENiHBG002902.
OMAiQPSQEEC.
OrthoDBiEOG091G0817.
TreeFamiTF332780.

Family and domain databases

CDDicd00094. HX. 1 hit.
Gene3Di2.110.10.10. 2 hits.
InterProiView protein in InterPro
IPR000585. Hemopexin-like_dom.
IPR036375. Hemopexin-like_dom_sf.
IPR018487. Hemopexin-like_repeat.
IPR018486. Hemopexin_CS.
IPR036024. Somatomedin_B-like_dom_sf.
IPR020436. Somatomedin_B_chordata.
IPR001212. Somatomedin_B_dom.
PfamiView protein in Pfam
PF00045. Hemopexin. 4 hits.
PF01033. Somatomedin_B. 1 hit.
PRINTSiPR00022. SOMATOMEDINB.
SMARTiView protein in SMART
SM00120. HX. 4 hits.
SM00201. SO. 1 hit.
SUPFAMiSSF50923. SSF50923. 3 hits.
SSF90188. SSF90188. 1 hit.
PROSITEiView protein in PROSITE
PS00024. HEMOPEXIN. 2 hits.
PS51642. HEMOPEXIN_2. 4 hits.
PS00524. SMB_1. 1 hit.
PS50958. SMB_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7TQ11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASLRPFFIL ALLALVSLAD QESCKGRCTQ GFMASKKCQC DELCTYYQSC
60 70 80 90 100
CVDYMEQCKP QVTRGDVFTM PEDEYWSYDY PEETKNSTST GVQSENTSLH
110 120 130 140 150
FNLKPRAEET IKPTTPDPQE QSNTQEPEVG QQGVAPRPDT TDEGTSEFPE
160 170 180 190 200
EELCSGKPFD AFTDLKNGSL FAFRGDSVDR FDGGEYCYEL DETAVRPGYP
210 220 230 240 250
KLIQDVWGIE GPIDAAFTRI NCQGKTYLFK GSQYWRFEDG VLDPDYPRNI
260 270 280 290 300
SEGFSGIPDN VDAALALPAH SYSGRERVYF FKGTQGKQYW EYEFQQQPSQ
310 320 330 340 350
EECEGSSLSA VFEHFALLQR DSWENIFELL FWGRSSDGAK GPQFISRDWH
360 370 380 390 400
GVPGKVDAAM AGRIYITGST FRSVQAKKQK SGRRSRKRYR SRRGRGHSRS
410 420 430 440 450
RSRSMSSRRP SRSVWFSLLS SEESGLGTYN YDYDMNWRIP ATCEPIQSVY
460 470 480 490
FFSGDKYYRV NLRTRRVDSV NPPYPRSIAQ YWLGCPTSEK
Length:490
Mass (Da):55,960
Last modified:October 1, 2003 - v1
Checksum:i0FCBCB6FF5C4E499
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07030074 Genomic DNA. No translation available.
AABR07030075 Genomic DNA. No translation available.
AY318963 mRNA. Translation: AAP85374.1.
UniGeneiRn.87493.

Genome annotation databases

EnsembliENSRNOT00000078897; ENSRNOP00000075508; ENSRNOG00000010031.

Similar proteinsi

Entry informationi

Entry nameiQ7TQ11_RAT
AccessioniPrimary (citable) accession number: Q7TQ11
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: November 22, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported