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Protein
Submitted name:

Aa1018

Gene

Vtn

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. extracellular matrix binding Source: Ensembl
  2. polysaccharide binding Source: InterPro
  3. scavenger receptor activity Source: InterPro

GO - Biological processi

  1. cell adhesion mediated by integrin Source: Ensembl
  2. extracellular matrix organization Source: Ensembl
  3. immune response Source: InterPro
  4. negative regulation of endopeptidase activity Source: Ensembl
  5. positive regulation of cell-substrate adhesion Source: Ensembl
  6. positive regulation of peptidyl-tyrosine phosphorylation Source: Ensembl
  7. positive regulation of protein binding Source: Ensembl
  8. positive regulation of receptor-mediated endocytosis Source: Ensembl
  9. positive regulation of smooth muscle cell migration Source: Ensembl
  10. smooth muscle cell-matrix adhesion Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_198300. Syndecan interactions.
REACT_198592. Molecules associated with elastic fibres.
REACT_198757. ECM proteoglycans.
REACT_199224. Regulation of Complement cascade.
REACT_252097. Integrin cell surface interactions.

Names & Taxonomyi

Protein namesi
Submitted name:
Aa1018Imported
Gene namesi
Name:VtnImported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi3967. Vtn.

Subcellular locationi

GO - Cellular componenti

  1. blood microparticle Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
  3. proteinaceous extracellular matrix Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ7TQ11.

Expressioni

Gene expression databases

ExpressionAtlasiQ7TQ11. baseline.
GenevestigatoriQ7TQ11.

Structurei

3D structure databases

ProteinModelPortaliQ7TQ11.
SMRiQ7TQ11. Positions 20-70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000133161.
HOVERGENiHBG002902.
PhylomeDBiQ7TQ11.
TreeFamiTF332780.

Family and domain databases

Gene3Di2.110.10.10. 3 hits.
InterProiIPR000585. Hemopexin-like_dom.
IPR018487. Hemopexin-like_repeat.
IPR018486. Hemopexin_CS.
IPR020436. Somatomedin_B_chordata.
IPR001212. Somatomedin_B_dom.
[Graphical view]
PfamiPF00045. Hemopexin. 4 hits.
PF01033. Somatomedin_B. 1 hit.
[Graphical view]
PRINTSiPR00022. SOMATOMEDINB.
SMARTiSM00120. HX. 4 hits.
SM00201. SO. 1 hit.
[Graphical view]
SUPFAMiSSF50923. SSF50923. 3 hits.
PROSITEiPS00024. HEMOPEXIN. 2 hits.
PS51642. HEMOPEXIN_2. 4 hits.
PS00524. SMB_1. 1 hit.
PS50958. SMB_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7TQ11-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASLRPFFIL ALLALVSLAD QESCKGRCTQ GFMASKKCQC DELCTYYQSC
60 70 80 90 100
CVDYMEQCKP QVTRGDVFTM PEDEYWSYDY PEETKNSTST GVQSENTSLH
110 120 130 140 150
FNLKPRAEET IKPTTPDPQE QSNTQEPEVG QQGVAPRPDT TDEGTSEFPE
160 170 180 190 200
EELCSGKPFD AFTDLKNGSL FAFRGDSVDR FDGGEYCYEL DETAVRPGYP
210 220 230 240 250
KLIQDVWGIE GPIDAAFTRI NCQGKTYLFK GSQYWRFEDG VLDPDYPRNI
260 270 280 290 300
SEGFSGIPDN VDAALALPAH SYSGRERVYF FKGTQGKQYW EYEFQQQPSQ
310 320 330 340 350
EECEGSSLSA VFEHFALLQR DSWENIFELL FWGRSSDGAK GPQFISRDWH
360 370 380 390 400
GVPGKVDAAM AGRIYITGST FRSVQAKKQK SGRRSRKRYR SRRGRGHSRS
410 420 430 440 450
RSRSMSSRRP SRSVWFSLLS SEESGLGTYN YDYDMNWRIP ATCEPIQSVY
460 470 480 490
FFSGDKYYRV NLRTRRVDSV NPPYPRSIAQ YWLGCPTSEK
Length:490
Mass (Da):55,960
Last modified:October 1, 2003 - v1
Checksum:i0FCBCB6FF5C4E499
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY318963 mRNA. Translation: AAP85374.1.
UniGeneiRn.87493.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY318963 mRNA. Translation: AAP85374.1.
UniGeneiRn.87493.

3D structure databases

ProteinModelPortaliQ7TQ11.
SMRiQ7TQ11. Positions 20-70.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ7TQ11.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

RGDi3967. Vtn.

Phylogenomic databases

HOGENOMiHOG000133161.
HOVERGENiHBG002902.
PhylomeDBiQ7TQ11.
TreeFamiTF332780.

Enzyme and pathway databases

ReactomeiREACT_198300. Syndecan interactions.
REACT_198592. Molecules associated with elastic fibres.
REACT_198757. ECM proteoglycans.
REACT_199224. Regulation of Complement cascade.
REACT_252097. Integrin cell surface interactions.

Miscellaneous databases

PROiQ7TQ11.

Gene expression databases

ExpressionAtlasiQ7TQ11. baseline.
GenevestigatoriQ7TQ11.

Family and domain databases

Gene3Di2.110.10.10. 3 hits.
InterProiIPR000585. Hemopexin-like_dom.
IPR018487. Hemopexin-like_repeat.
IPR018486. Hemopexin_CS.
IPR020436. Somatomedin_B_chordata.
IPR001212. Somatomedin_B_dom.
[Graphical view]
PfamiPF00045. Hemopexin. 4 hits.
PF01033. Somatomedin_B. 1 hit.
[Graphical view]
PRINTSiPR00022. SOMATOMEDINB.
SMARTiSM00120. HX. 4 hits.
SM00201. SO. 1 hit.
[Graphical view]
SUPFAMiSSF50923. SSF50923. 3 hits.
PROSITEiPS00024. HEMOPEXIN. 2 hits.
PS51642. HEMOPEXIN_2. 4 hits.
PS00524. SMB_1. 1 hit.
PS50958. SMB_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Liver regeneration after PH."
    Xu C.S., Li W.Q., Li Y.C., Han H.P., Wang G.P., Chai L.Q., Yuan J.Y., Yang K.J., Yan H.M., Chang C.F., Zhao L.F., Ma H., Wang L., Wang S.F., Shi J.B., Rahman S., Wang Q.N., Zhang J.B.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ7TQ11_RAT
AccessioniPrimary (citable) accession number: Q7TQ11
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: November 26, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.