ID   LDOC1_MOUSE             Reviewed;         151 AA.
AC   Q7TPY9; B1AV12;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   27-MAR-2024, entry version 118.
DE   RecName: Full=Protein LDOC1;
GN   Name=Ldoc1; Synonyms=Gm366;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Egg;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Embryo;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
CC   -!- FUNCTION: May have an important role in the development and/or
CC       progression of some cancers. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with NOD2. {ECO:0000250|UniProtKB:O95751}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LDOC1 family. {ECO:0000305}.
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DR   EMBL; AL672025; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC052689; AAH52689.1; -; mRNA.
DR   EMBL; AK137057; BAE23221.1; -; mRNA.
DR   CCDS; CCDS30163.1; -.
DR   RefSeq; NP_001018097.1; NM_001018087.1.
DR   AlphaFoldDB; Q7TPY9; -.
DR   SMR; Q7TPY9; -.
DR   STRING; 10090.ENSMUSP00000075366; -.
DR   PaxDb; 10090-ENSMUSP00000075366; -.
DR   Antibodypedia; 16816; 231 antibodies from 26 providers.
DR   DNASU; 434784; -.
DR   Ensembl; ENSMUST00000075983.6; ENSMUSP00000075366.5; ENSMUSG00000057615.6.
DR   GeneID; 434784; -.
DR   KEGG; mmu:434784; -.
DR   UCSC; uc009tij.1; mouse.
DR   AGR; MGI:2685212; -.
DR   CTD; 23641; -.
DR   MGI; MGI:2685212; Ldoc1.
DR   VEuPathDB; HostDB:ENSMUSG00000057615; -.
DR   eggNOG; ENOG502T19P; Eukaryota.
DR   GeneTree; ENSGT00940000162721; -.
DR   HOGENOM; CLU_154949_0_0_1; -.
DR   InParanoid; Q7TPY9; -.
DR   OMA; IENNQLM; -.
DR   OrthoDB; 5256898at2759; -.
DR   PhylomeDB; Q7TPY9; -.
DR   TreeFam; TF337843; -.
DR   BioGRID-ORCS; 434784; 2 hits in 60 CRISPR screens.
DR   PRO; PR:Q7TPY9; -.
DR   Proteomes; UP000000589; Chromosome X.
DR   RNAct; Q7TPY9; Protein.
DR   Bgee; ENSMUSG00000057615; Expressed in ectoplacental cone and 47 other cell types or tissues.
DR   GO; GO:0005730; C:nucleolus; ISO:MGI.
DR   GO; GO:0005654; C:nucleoplasm; ISO:MGI.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0071225; P:cellular response to muramyl dipeptide; ISS:UniProtKB.
DR   GO; GO:0001893; P:maternal placenta development; IMP:MGI.
DR   GO; GO:0060137; P:maternal process involved in parturition; IMP:MGI.
DR   InterPro; IPR032549; DUF4939.
DR   InterPro; IPR032567; LDOC1-rel.
DR   PANTHER; PTHR15503:SF22; CCHC-TYPE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR15503; LDOC1 RELATED; 1.
DR   Pfam; PF16297; DUF4939; 1.
DR   Genevisible; Q7TPY9; MM.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..151
FT                   /note="Protein LDOC1"
FT                   /id="PRO_0000084392"
FT   REGION          132..151
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        134..151
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   151 AA;  17546 MW;  6E923EAAD774419D CRC64;
     MVEELLSLLH ALLDRHQALC MENHQLLKQL RLLVCERARL LRQVCPPSCP VPYPSRFSGE
     SGRLPEFIMQ TMSYMLANEE HFCNDAMKVA FLISLLSGEA EEWVMPYIES NSYVLGDYQA
     FVDEMKQYFG WGTDDEDDGD DDEEEEMEED H
//