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Protein

Protein LDOC1

Gene

Ldoc1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May have an important role in the development and/or progression of some cancers.By similarity

GO - Biological processi

  1. negative regulation of cell proliferation Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein LDOC1
Gene namesi
Name:Ldoc1
Synonyms:Gm366
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:2685212. Ldoc1.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleolus Source: MGI
  2. nucleus Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 151151Protein LDOC1PRO_0000084392Add
BLAST

Proteomic databases

PRIDEiQ7TPY9.

Expressioni

Gene expression databases

BgeeiQ7TPY9.
CleanExiMM_LDOC1.
GenevestigatoriQ7TPY9.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi134 – 15017Asp/Glu-rich (highly acidic)Add
BLAST

Sequence similaritiesi

Belongs to the LDOC1 family.Curated

Phylogenomic databases

eggNOGiNOG46550.
GeneTreeiENSGT00510000047956.
HOGENOMiHOG000049195.
HOVERGENiHBG052318.
InParanoidiQ7TPY9.
OMAiEFIVQTT.
OrthoDBiEOG76HQ3K.
PhylomeDBiQ7TPY9.
TreeFamiTF337843.

Family and domain databases

InterProiIPR029750. LDOC1.
[Graphical view]
PANTHERiPTHR15503:SF3. PTHR15503:SF3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7TPY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVEELLSLLH ALLDRHQALC MENHQLLKQL RLLVCERARL LRQVCPPSCP
60 70 80 90 100
VPYPSRFSGE SGRLPEFIMQ TMSYMLANEE HFCNDAMKVA FLISLLSGEA
110 120 130 140 150
EEWVMPYIES NSYVLGDYQA FVDEMKQYFG WGTDDEDDGD DDEEEEMEED

H
Length:151
Mass (Da):17,546
Last modified:September 30, 2003 - v1
Checksum:i6E923EAAD774419D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL672025 Genomic DNA. Translation: CAM20842.1.
BC052689 mRNA. Translation: AAH52689.1.
AK137057 mRNA. Translation: BAE23221.1.
CCDSiCCDS30163.1.
RefSeqiNP_001018097.1. NM_001018087.1.
UniGeneiMm.23468.

Genome annotation databases

EnsembliENSMUST00000075983; ENSMUSP00000075366; ENSMUSG00000057615.
GeneIDi434784.
KEGGimmu:434784.
UCSCiuc009tij.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL672025 Genomic DNA. Translation: CAM20842.1.
BC052689 mRNA. Translation: AAH52689.1.
AK137057 mRNA. Translation: BAE23221.1.
CCDSiCCDS30163.1.
RefSeqiNP_001018097.1. NM_001018087.1.
UniGeneiMm.23468.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ7TPY9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000075983; ENSMUSP00000075366; ENSMUSG00000057615.
GeneIDi434784.
KEGGimmu:434784.
UCSCiuc009tij.1. mouse.

Organism-specific databases

CTDi23641.
MGIiMGI:2685212. Ldoc1.

Phylogenomic databases

eggNOGiNOG46550.
GeneTreeiENSGT00510000047956.
HOGENOMiHOG000049195.
HOVERGENiHBG052318.
InParanoidiQ7TPY9.
OMAiEFIVQTT.
OrthoDBiEOG76HQ3K.
PhylomeDBiQ7TPY9.
TreeFamiTF337843.

Miscellaneous databases

NextBioi409851.
PROiQ7TPY9.
SOURCEiSearch...

Gene expression databases

BgeeiQ7TPY9.
CleanExiMM_LDOC1.
GenevestigatoriQ7TPY9.

Family and domain databases

InterProiIPR029750. LDOC1.
[Graphical view]
PANTHERiPTHR15503:SF3. PTHR15503:SF3. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Egg.
  3. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Embryo.

Entry informationi

Entry nameiLDOC1_MOUSE
AccessioniPrimary (citable) accession number: Q7TPY9
Secondary accession number(s): B1AV12
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 19, 2005
Last sequence update: September 30, 2003
Last modified: March 3, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.